Mechanisms for Reversible Regulation between G13 and Rho Exchange Factors

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

GTPase-Activating Proteins for Heterotrimeric G Proteins: Regulators of G Protein Signaling (RGS) and RGS-Like Proteins

2000 • 1,143 citations

G proteins

1992 • 871 citations

p115 RhoGEF, a GTPase Activating Protein for Gα ₁₂ and Gα ₁₃

1998 • 834 citations

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα ₁₃

1998 • 765 citations

GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

1996 • 729 citations

EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins

1996 • 573 citations

RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunits

1996 • 547 citations

The Dbl family of oncogenes

1996 • 497 citations

Mammalian RGS Proteins: Barbarians at the Gate

1998 • 487 citations

Gα12 and Gα13 Stimulate Rho-dependent Stress Fiber Formation and Focal Adhesion Assembly

1995 • 443 citations

A Novel PDZ Domain Containing Guanine Nucleotide Exchange Factor Links Heterotrimeric G Proteins to Rho

1999 • 386 citations

RGS4 and GAIP are GTPase-activating proteins for G _qα and block activation of phospholipase Cβ by γ-thio-GTP-G _qα

1997 • 355 citations

The GTPase-activating Protein RGS4 Stabilizes the Transition State for Nucleotide Hydrolysis

1996 • 354 citations

RGS10 is a selective activator of Gαi GTPase activity

1996 • 354 citations

The Role of Rho in G Protein-Coupled Receptor Signal Transduction

2000 • 345 citations

Vascular System Defects and Impaired Cell Chemokinesis as a Result of Gα ₁₃ Deficiency

1997 • 340 citations

Purification of Recombinant G Proteins from Sf9 Cells by Hexahistidine Tagging of Associated Subunits

1995 • 332 citations

The drosophila gastrulation gene concertina encodes a Gα-like protein

1991 • 319 citations

The G-protein G13 but Not G12 Mediates Signaling from Lysophosphatidic Acid Receptor via Epidermal Growth Factor Receptor to Rho

1998 • 265 citations

Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 Å

2001 • 260 citations

G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits.

1991 • 250 citations

Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins

2001 • 241 citations

Regulation and function of the Rho subfamily of small GTPases

1994 • 233 citations

Leukemia‐associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G₁₂ family to Rho

2000 • 224 citations

Structural basis of the Axin–adenomatous polyposis coli interaction

2000 • 203 citations

Overexpression of fIbA, an early regulator of Aspergillus asexual sporulation, leads to activation of brIA and premature initiation of development

1994 • 200 citations

Inhibition of G-Protein Signaling by Dominant Gain-of-Function Mutations in Sst2p, a Pheromone Desensitization Factor in Saccharomyces cerevisiae

1995 • 198 citations

The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro

1997 • 167 citations

Identification of a Novel Guanine Nucleotide Exchange Factor for the Rho GTPase

1996 • 161 citations

Mechanism of RGS4, a GTPase-activating Protein for G Protein α Subunits

1998 • 122 citations

Pleckstrin Homology Domains

1998 • 112 citations

The transforming activity of activated Gα12

1993 • 100 citations

Purification and characterization of the alpha subunit of G13.

1994 • 75 citations

Identification of Potential Mechanisms for Regulation of p115 RhoGEF through Analysis of Endogenous and Mutant Forms of the Exchange Factor

2001 • 75 citations

Structure of the RGS-like Domain from PDZ-RhoGEF

2001 • 71 citations

Solution structure of human GAIP (Gα interacting protein): a regulator of G protein signaling

1999 • 67 citations

Structure of the rgRGS domain of p115RhoGEF.

2001 • 57 citations

Functional Characterization of p115 RhoGEF

2002 • 15 citations

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