Solution structure of human GAIP (Gα interacting protein): a regulator of G protein signaling

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

MOLMOL: A program for display and analysis of macromolecular structures

1996 • 7,169 citations

AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR

1996 • 5,190 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

Protein backbone angle restraints from searching a database for chemical shift and sequence homology.

1999 • 2,966 citations

Direct Measurement of Distances and Angles in Biomolecules by NMR in a Dilute Liquid Crystalline Medium

1997 • 1,695 citations

Heterotrimeric C proteins: Organizers of transmembrane signals

1995 • 1,388 citations

Empirical correlation between protein backbone conformation and C.alpha. and C.beta. 13C nuclear magnetic resonance chemical shifts

1991 • 1,072 citations

Correlating backbone amide and side chain resonances in larger proteins by multiple relayed triple resonance NMR

1992 • 1,012 citations

Measurement ofJand Dipolar Couplings from Simplified Two-Dimensional NMR Spectra

1998 • 968 citations

G proteins

1992 • 871 citations

p115 RhoGEF, a GTPase Activating Protein for Gα ₁₂ and Gα ₁₃

1998 • 834 citations

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

1994 • 823 citations

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα ₁₃

1998 • 765 citations

GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

1996 • 729 citations

Methodological Advances in Protein NMR

1993 • 721 citations

Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions

1998 • 694 citations

Amino acid type determination in the sequential assignment procedure of uniformly 13C/15N-enriched proteins

1993 • 692 citations

Methodological advances in protein NMR

1993 • 686 citations

A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams

1991 • 682 citations

STRUCTURE AND FUNCTION OF SIGNAL-TRANSDUCING GTP-BINDING PROTEINS

1991 • 630 citations

1H1H correlation via isotropic mixing of 13C magnetization, a new three-dimensional approach for assigning 1H and 13C spectra of 13C-enriched proteins

1990 • 580 citations

EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins

1996 • 573 citations

Mammalian RGS Proteins: Barbarians at the Gate

1998 • 487 citations

Use of dipolar 1H–15N and 1H–13C couplings in the structure determination of magnetically oriented macromolecules in solution

1997 • 476 citations

Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

1996 • 470 citations

G proteins control diverse pathways of transmembrane signaling ¹

1989 • 399 citations

A Robust Method for Determining the Magnitude of the Fully Asymmetric Alignment Tensor of Oriented Macromolecules in the Absence of Structural Information

1998 • 380 citations

RGS4 and GAIP are GTPase-activating proteins for G _qα and block activation of phospholipase Cβ by γ-thio-GTP-G _qα

1997 • 355 citations

Enhanced-Sensitivity Triple-Resonance Spectroscopy with Minimal H2O Saturation

1994 • 354 citations

The GTPase-activating Protein RGS4 Stabilizes the Transition State for Nucleotide Hydrolysis

1996 • 354 citations

Heterotrimeric G proteins

1996 • 318 citations

Measurement of Residual Dipolar Couplings of Macromolecules Aligned in the Nematic Phase of a Colloidal Suspension of Rod-Shaped Viruses

1998 • 312 citations

Four-Dimensional Heteronuclear Triple-Resonance NMR Spectroscopy of Interleukin-1β in Solution

1990 • 308 citations

Direct Structure Refinement against Residual Dipolar Couplings in the Presence of Rhombicity of Unknown Magnitude

1998 • 301 citations

GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain.

1995 • 291 citations

An alternative 3D NMR technique for correlating backbone 15N with side chain Hβ resonances in larger proteins

1991 • 273 citations

RGS Proteins Determine Signaling Specificity of Gq-coupled Receptors

1999 • 256 citations

GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP

1998 • 222 citations

RGS proteins: more than just GAPs for heterotrimeric G proteins

1999 • 200 citations

High-resolution heteronuclear NMR of human ubiquitin in an aqueous liquid crystalline medium.

1997 • 182 citations

Bicelle-based liquid crystals for NMR-measurement of dipolar couplings at acidic and basic pH values.

1999 • 172 citations

The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro

1997 • 167 citations

GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of Gα _i subunits

1996 • 166 citations

Four-dimensional carbon-13/carbon-13-edited nuclear Overhauser enhancement spectroscopy of a protein in solution: application to interleukin 1.beta.

1991 • 162 citations

An HNCA Pulse Scheme for the Backbone Assignment of 15N,13C,2H-Labeled Proteins: Application to a 37-kDa Trp Repressor-DNA Complex

1994 • 159 citations

RGSZ1, a Gz-selective RGS Protein in Brain

1998 • 144 citations

2D and 3D NMR Study of Phenylalanine Residues in Proteins by Reverse Isotopic Labeling

1994 • 128 citations

Measurement of Dipolar Couplings for Methylene and Methyl Sites in Weakly Oriented Macromolecules and Their Use in Structure Determination

1998 • 119 citations

RGS-GAIP, a GTPase-activating Protein for Gα_iHeterotrimeric G Proteins, Is Located on Clathrin-coated Vesicles

1998 • 94 citations

The use of dipolar couplings for determining the solution structure of rat apo‐S100B(ββ)

1999 • 91 citations

The core domain of a new retina specific RGS protein stimulates the GTPase activity of transducin in vitro

1997 • 90 citations

Mutational Analysis of the Asn Residue Essential for RGS Protein Binding to G-proteins

1998 • 43 citations

The core domain of RGS16 retains G‐protein binding and GAP activity in vitro, but is not functional in vivo

1998 • 39 citations

Clathrin-coated vesicles bearing GAIP possess GTPase-activating protein activity in vitro

1999 • 24 citations