Leukemia‐associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G₁₂ family to Rho

Proteins regulating Ras and its relatives

1993 • 1,930 citations

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

1995 • 1,653 citations

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1999 • 1,558 citations

Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development

1998 • 1,551 citations

The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

1995 • 1,280 citations

p115 RhoGEF, a GTPase Activating Protein for Gα ₁₂ and Gα ₁₃

1998 • 834 citations

Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα ₁₃

1998 • 765 citations

Mammalian RGS Proteins: Barbarians at the Gate

1998 • 487 citations

Gα12 and Gα13 Stimulate Rho-dependent Stress Fiber Formation and Focal Adhesion Assembly

1995 • 443 citations

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product

1991 • 424 citations

The Small GTPase Rho: Cellular Functions and Signal Transduction

1996 • 404 citations

A Novel PDZ Domain Containing Guanine Nucleotide Exchange Factor Links Heterotrimeric G Proteins to Rho

1999 • 386 citations

Rho effectors and reorganization of actin cytoskeleton

1997 • 379 citations

The Role of Rho in G Protein-Coupled Receptor Signal Transduction

2000 • 345 citations

The drosophila gastrulation gene concertina encodes a Gα-like protein

1991 • 319 citations

Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product.

1994 • 314 citations

DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila

1998 • 309 citations

Protein–protein interactions: PDZ domain networks

1996 • 292 citations

Dbl family proteins

1997 • 260 citations

GAPs for rho-related GTPases

1994 • 248 citations

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: Evidence for its fusion with MLL in acute myeloid leukemia

2000 • 223 citations

The small GTP-binding protein Rho links G protein-coupled receptors and Gα ₁₂ to the serum response element and to cellular transformation

1997 • 211 citations

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells.

1993 • 176 citations

Specific Involvement of G Proteins in Regulation of Serum Response Factor-mediated Gene Transcription by Different Receptors

1998 • 167 citations

Potent Transforming Activity of the G13 α Subunit Defines a Novel Family of Oncogenes

1994 • 99 citations

Signaling from G Protein-coupled Receptors to ERK5/Big MAPK 1 Involves Gαq and Gα12/13 Families of Heterotrimeric G Proteins

2000 • 92 citations

Regulation of the actin cytoskeleton, integrins and cell growth by the Rho family of small GTPases.

1996 • 56 citations