Functional evidence for a single endodermal origin for the thymic epithelium

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Immunobiology: the immune system in health and disease

1995 • 3,893 citations

Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

2002 • 2,371 citations

IMMUNOBIOLOGY : the immunesystem in health and disease

2001 • 1,685 citations

Fate of the mammalian cardiac neural crest

2000 • 1,123 citations

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

2001 • 1,043 citations

Mesenchymal derivatives of the neural crest: analysis of chimaeric quail and chick embryos

1975 • 966 citations

‘Nude’, a new hairless gene with pleiotropic effects in the mouse

1966 • 834 citations

New member of the winged-helix protein family disrupted in mouse and rat nude mutations

1994 • 651 citations

Vertebrate Endoderm Development

1999 • 517 citations

Cellular Interactions in Thymocyte Development

1996 • 503 citations

Dependence of Thymus Development on Derivatives of the Neural Crest

1984 • 463 citations

Lymphostromal interactions in thymic development and function

2001 • 461 citations

The thymic microenvironment

1993 • 459 citations

Two Genetically Separable Steps in the Differentiation of Thymic Epithelium

1996 • 447 citations

Tracing of cells of the avian thymus through embryonic life in interspecific chimeras.

1975 • 409 citations

Mapping Precursor Movement through the Postnatal Thymus Reveals Specific Microenvironments Supporting Defined Stages of Early Lymphoid Development

2001 • 394 citations

MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus

1993 • 359 citations

Morphogenetic interactions in the development of the mouse thymus gland

1960 • 336 citations

The Immune System

2000 • 313 citations

Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment

1998 • 292 citations

Generation of a complete thymic microenvironment by MTS24+ thymic epithelial cells

2002 • 290 citations

Identification and Characterization of Thymic Epithelial Progenitor Cells

2002 • 269 citations

Development of thymus, parathyroids, and ultimo‐branchial bodies in NMRI and nude mice

1980 • 264 citations

Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice

2002 • 254 citations

Developing a new paradigm for thymus organogenesis

2004 • 242 citations

Development of the Thymus Requires Signaling Through the Fibroblast Growth Factor Receptor R2-IIIb

2001 • 241 citations

Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch

2001 • 237 citations

Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal Thymus

2003 • 229 citations

The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors.

1996 • 225 citations

Thymus medulla consisting of epithelial islets each derived from a single progenitor

2001 • 211 citations

Cell migration and the control of post-natal T-cell lymphopoiesis in the thymus

2003 • 186 citations

Major histocompatibility complex antigen expression on the epithelium of the developing thymus in normal and nude mice.

1981 • 165 citations

Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation

2000 • 162 citations

Hoxa3 and Pax1 Regulate Epithelial Cell Death and Proliferation during Thymus and Parathyroid Organogenesis

2001 • 151 citations

The phenotypic heterogeneity of mouse thymic stromal cells.

1990 • 104 citations

Role of thymic organ structure and stromal composition in steady‐state postnatal T‐cell production

2002 • 99 citations

Monoclonal antibodies reactive with subsets of mouse and human thymic epithelial cells.

1988 • 94 citations

Stromal Cells Provide the Matrix for Migration of Early Lymphoid Progenitors Through the Thymic Cortex

2002 • 91 citations

A developmental look at thymus organogenesis: where do the non-hematopoietic cells in the thymus come from?

2003 • 89 citations

Nude Mouse Embryo: Ectodermal Nature of the Primordial Thymic Defect

1975 • 72 citations

Detection of Thy‐1, T‐200, Lyt‐1 and Lyt‐2‐bearing cells in the developing lymphoid organs of the mouse embryo in vivo and in vitro

1982 • 64 citations

Studies on the thymus of the mammal. XIV. Histology and histochemistry of embryonic and early postnatal thymuses of C57Bl/6 and AKR strain mice

1965 • 51 citations

Sox3 Expression Defines a Common Primordium for the Epibranchial Placodes in Chick

2001 • 34 citations

New serum‐free in vitro culture technique for midgestation mouse embryos

2003 • 30 citations

A Novel Adhesion Molecule in the Murine Thymic Microenvironment: Functional and Biochemical Analysis

1992 • 18 citations