Cell migration and the control of post-natal T-cell lymphopoiesis in the thymus

Adhesion receptors of the immune system

1990 • 6,585 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1998 • 2,496 citations

Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

1997 • 2,205 citations

Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1

1999 • 1,392 citations

Induction of T Cell Development from Hematopoietic Progenitor Cells by Delta-like-1 In Vitro

2002 • 1,095 citations

Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

1993 • 673 citations

Multiple roles of eph receptors and ephrins in neural development

2001 • 611 citations

The intestinal epithelial stem cell

2002 • 578 citations

Thymopoiesis independent of common lymphoid progenitors

2003 • 548 citations

EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS

1967 • 504 citations

CCR6 Mediates Dendritic Cell Localization, Lymphocyte Homeostasis, and Immune Responses in Mucosal Tissue

2000 • 485 citations

Transcription from the RAG1 Locus Marks the Earliest Lymphocyte Progenitors in Bone Marrow

2002 • 460 citations

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

2001 • 443 citations

Tracing of cells of the avian thymus through embryonic life in interspecific chimeras.

1975 • 409 citations

Mapping Precursor Movement through the Postnatal Thymus Reveals Specific Microenvironments Supporting Defined Stages of Early Lymphoid Development

2001 • 394 citations

Integrin-Mediated Long-Term B Cell Retention in the Splenic Marginal Zone

2002 • 381 citations

The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9

2000 • 358 citations

Rapid leukocyte integrin activation by chemokines

2002 • 341 citations

The Sertoli-Germ Cell Communication Network in Mammals

1993 • 341 citations

The generation and fate of thymocytes.

1990 • 309 citations

TISSUE INTERACTION IN THE DEVELOPMENT OF THYMUS LYMPHOCYTES

1969 • 295 citations

TECK: A Novel CC Chemokine Specifically Expressed by Thymic Dendritic Cells and Potentially Involved in T Cell Development

1997 • 292 citations

Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor γδ+ gut intraepithelial lymphocytes

2001 • 291 citations

Dynamics of Thymocyte-Stromal Cell Interactions Visualized by Two-Photon Microscopy

2002 • 278 citations

Stem cell fate and patterning in mammalian epidermis

2001 • 250 citations

Cutting Edge: Developmental Switches in Chemokine Responses During T Cell Maturation

1999 • 247 citations

Role for CCR7 Ligands in the Emigration of Newly Generated T Lymphocytes from the Neonatal Thymus

2002 • 218 citations

Chemokines define distinct microenvironments in the developing thymus

2000 • 218 citations

Aberrant in Vivo T Helper Type 2 Cell Response and Impaired Eosinophil Recruitment in Cc Chemokine Receptor 8 Knockout Mice

2001 • 215 citations

The Importation of Hematogenous Precursors by the Thymus Is a Gated Phenomenon in Normal Adult Mice

2001 • 213 citations

Commitment of Common T/Natural Killer (Nk) Progenitors to Unipotent T and Nk Progenitors in the Murine Fetal Thymus Revealed by a Single Progenitor Assay

1999 • 169 citations

T-cell lineage commitment and cytokine responses of thymic progenitors

1995 • 164 citations

A pertussis toxin‐sensitive process controls thymocyte emigration

1991 • 147 citations

Hyaluronan is synthesized by primitive hemopoietic cells, participates in their lodgment at the endosteum following transplantation, and is involved in the regulation of their proliferation and differentiation in vitro

2003 • 143 citations

Intrathymic T-cell migration: a combinatorial interplay of extracellular matrix and chemokines?

2002 • 137 citations

Presentation of chemokine SDF-1α by fibronectin mediates directed migration of T cells

2000 • 131 citations

RGS13 Regulates Germinal Center B Lymphocytes Responsiveness to CXC Chemokine Ligand (CXCL)12 and CXCL13

2002 • 130 citations

Pertussis Toxin-Sensitive Signal Controls the Trafficking of Thymocytes Across the Corticomedullary Junction in the Thymus

1999 • 123 citations

Thymocyte emigration is mediated by active movement away from stroma-derived factors

2002 • 104 citations

Macrophage-Derived Chemokine Is Localized to Thymic Medullary Epithelial Cells and Is a Chemoattractant for CD3+, CD4+, CD8low Thymocytes

1999 • 103 citations

Characterization of CCR9 Expression and CCL25/Thymus-Expressed Chemokine Responsiveness During T Cell Development: CD3highCD69+ Thymocytes and γδTCR+ Thymocytes Preferentially Respond to CCL25

2002 • 102 citations

Murine CCR9, a Chemokine Receptor for Thymus-Expressed Chemokine That Is Up-Regulated Following Pre-TCR Signaling

2000 • 101 citations

Extracellular matrix proteins in intrathymic T-cell migration and differentiation?

1993 • 100 citations

Factors Regulating Stem Cell Recruitment to the Fetal Thymus

1999 • 97 citations

Extracellular matrix components of the mouse thymus microenvironment: ontogenetic studies and modulation by glucocorticoid hormones.

1991 • 94 citations

Cell adhesion and migration are regulated at distinct stages of thymic T cell development: the roles of fibronectin, VLA4, and VLA5.

1996 • 93 citations

Stromal Cells Provide the Matrix for Migration of Early Lymphoid Progenitors Through the Thymic Cortex

2002 • 91 citations

Ontogeny of the Immune System: γ/δ and α/β T Cells Migrate from Thymus to the Periphery in Alternating Waves

1997 • 91 citations

Thymocyte emigration is mediated by active movement away from stroma-derived factors

2002 • 89 citations

The embryonic thymus produces chemotactic peptides involved in the homing of hemopoietic precursors

1986 • 86 citations

Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes.

1996 • 84 citations

Role of chemokines in thymocyte development

2000 • 83 citations

The CD44 expressed on the earliest intrathymic precursor population functions as a thymus homing molecule but does not bind to hyaluronate

1993 • 75 citations

Nature or nurture? Steady‐state lymphocyte formation in adults does not recapitulate ontogeny

2002 • 72 citations

Expression of VLA-4 on thymocytes. Maturation stage-associated transition and its correlation with their capacity to adhere to thymic stromal cells.

1992 • 60 citations

Developmentally regulated expression of the beta 4 integrin on immature mouse thymocytes.

1992 • 56 citations

Graded Positional Information

2003 • 51 citations

Selectins, T-cell rolling and inflammation

1997 • 49 citations

Epithelial Cell-Specific Laminin 5 Is Required for Survival of Early Thymocytes

2000 • 49 citations

Loss of SDF-1 receptor expression during positive selection in the thymus

1998 • 48 citations

α₆ integrins participate in pro‐T cell homing to the thymus

1995 • 48 citations

Stromal-Derived Factor 1 Expression in the Human Thymus

2002 • 47 citations

Studies on the phenotype of migrant thymic stem cells

1999 • 41 citations

The Transient Expression of C-C Chemokine Receptor 8 in Thymus Identifies a Thymocyte Subset Committed to Become CD4+ Single-Positive T Cells

2001 • 41 citations

Penetration of thymocytes into the blood circulation

1967 • 40 citations

Roles of Integrins and CD44 on the Adhesion and Migration of Fetal Liver Cells to the Fetal Thymus

1999 • 39 citations

Microenvironmental regulation of Notch signalling in T cell development

2003 • 37 citations

Role of the CC chemokine receptor 9/TECK interaction in apoptosis.

2002 • 36 citations

Characterization of Vascular Adhesion Molecules that may Facilitate Progenitor Homing in the Post‐natal Mouse Thymus

2003 • 31 citations

Enhancement of stromal cell‐derived factor‐1α‐induced chemotaxis for CD4/8 double‐positive thymocytes by fibronectin and laminin in mice

2001 • 30 citations

Characterization of lymphatic and venous emigrants from the thymus.

1990 • 26 citations

Elaboration of a Model for the Formation of Lymphocytes in the Thymic Cortex of Young Adult Rats

1965 • 25 citations

Three-dimensional Ultrastructure of the Perivascular Space in the Rat Thymus.

1997 • 20 citations

Surface morphology of mouse and rat thymic lymphocytes: An in situ scanning electron microscopic study

1978 • 15 citations

RETRACTED: Compartmentalized Eph receptor and ephrin expression in the thymus

2002 • 9 citations