The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors.

IMMUNOLOGICAL FUNCTION OF THE THYMUS

1961 • 1,359 citations

Properties of Monoclonal Antibodies to Mouse Ig Allotypes, H-2, and Ia Antigens

1979 • 993 citations

‘Nude’, a new hairless gene with pleiotropic effects in the mouse

1966 • 834 citations

Culture of mouse ova.

1971 • 810 citations

New member of the winged-helix protein family disrupted in mouse and rat nude mutations

1994 • 651 citations

T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views.

1980 • 574 citations

The thymic microenvironment

1993 • 459 citations

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

1994 • 430 citations

Tracing of cells of the avian thymus through embryonic life in interspecific chimeras.

1975 • 409 citations

Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes

1995 • 295 citations

Development in the thymus: it takes two to tango

1993 • 281 citations

Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic β cells

1988 • 266 citations

Hox11 controls the genesis of the spleen

1994 • 261 citations

Clonal analysis of B- and T-cell responses to Ia antigens

1981 • 205 citations

A rat antibody against a structure functionally related to the mouse T-cell receptor/T3 complex

1988 • 205 citations

Localization of allodeterminants on H-2Kb antigens determined with monoclonal antibodies and H-2 mutant mice.

1982 • 194 citations

Major histocompatibility complex antigen expression on the epithelium of the developing thymus in normal and nude mice.

1981 • 165 citations

ABNORMAL DEVELOPMENT OF THE THYMUS IN "NUDE" MICE

1971 • 155 citations

GENE CONTROL OF MAMMALIAN DIFFERENTIATION

1974 • 149 citations

Growth of epithelial cells in the thymic medulla is under the control of mature T cells.

1992 • 128 citations

Effects of cytotoxic monoclonal antibody specific for T200 glycoprotein on functional lymphoid cell populations

1980 • 125 citations

The phenotypic heterogeneity of mouse thymic stromal cells.

1990 • 104 citations

Downstream of the homeotic genes.

1992 • 74 citations

Nude Mouse Embryo: Ectodermal Nature of the Primordial Thymic Defect

1975 • 72 citations

Athymic Development in the Mouse

1973 • 69 citations

Thymus rudiment of the athymic nude mouse

1975 • 40 citations

A nondeletional mechanism of peripheral tolerance in T-cell receptor transgenic mice.

1991 • 34 citations

A yeast artificial chromosome contig on mouse chromosome 11 encompassing the nu locus

1994 • 13 citations

A high-resolution map of the chromosomal region surrounding the nude gene

1995 • 10 citations

Thymus differentiation and T-cell specificity in nu/nu +/+ mouse aggregation chimaeras.

1983 • 7 citations