Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes

AP-1 function and regulation

1997 • 2,833 citations

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

1996 • 2,387 citations

Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization

1998 • 2,096 citations

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways

1996 • 1,519 citations

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

1995 • 1,017 citations

Specific protection against breast cancers by cyclin D1 ablation

2001 • 930 citations

Cyclin‐dependent protein kinases: Key regulators of the eukaryotic cell cycle

1995 • 918 citations

A human peptidyl–prolyl isomerase essential for regulation of mitosis

1996 • 891 citations

Sequence-Specific and Phosphorylation-Dependent Proline Isomerization: A Potential Mitotic Regulatory Mechanism

1997 • 762 citations

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway.

1997 • 747 citations

AP-1 in mouse development and tumorigenesis

2001 • 727 citations

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

1999 • 701 citations

Lack of β-catenin affects mouse development at gastrulation

1995 • 700 citations

Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis

1996 • 700 citations

Structural and Functional Analysis of the Mitotic Rotamase Pin1 Suggests Substrate Recognition Is Phosphorylation Dependent

1997 • 681 citations

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1995 • 681 citations

Structural basis for phosphoserine-proline recognition by group IV WW domains.

2000 • 677 citations

Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining.

1994 • 673 citations

Function of WW Domains as Phosphoserine- or Phosphothreonine-Binding Modules

1999 • 663 citations

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1–dependent cellular transformation

2000 • 529 citations

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1

2001 • 525 citations

Cyclin D1 protein expression and function in human breast cancer

1994 • 515 citations

Function of a human cyclin gene as an oncogene.

1994 • 471 citations

Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with APC

2001 • 460 citations

The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

1998 • 340 citations

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

1998 • 220 citations

Mice Lacking Pin1 Develop Normally, but Are Defective in Entering Cell Cycle from G0 Arrest

1999 • 212 citations

The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1

1998 • 188 citations

Pin1 Acts Catalytically to Promote a Conformational Change in Cdc25

2001 • 165 citations

The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery

2000 • 163 citations

Phospho-Carboxyl-Terminal Domain Binding and the Role of a Prolyl Isomerase in Pre-mRNA 3′-End Formation

1999 • 147 citations

Phosphorylation-dependent prolyl isomerization: a novel signaling regulatory mechanism

1999 • 134 citations

INK4d-Deficient Mice Are Fertile Despite Testicular Atrophy

2000 • 129 citations

Control of Spermatogenesis in Mice by the Cyclin D-Dependent Kinase Inhibitors p18^Ink4cand p19^Ink4d

2001 • 117 citations

Prolyl Isomerases and Nuclear Function

1998 • 117 citations

The Xenopus Suc1/Cks Protein Promotes the Phosphorylation of G2/M Regulators

1999 • 104 citations

Drosophila Pin1 prolyl isomerase Dodo is a MAP kinase signal responder during oogenesis

2001 • 82 citations

A hyperphosphorylated form of RNA polymerase II is the major interphase antigen of the phosphoprotein antibody MPM-2 and interacts with the peptidyl-prolyl isomerase Pin1

1999 • 74 citations

Progesterone Action in Normal Mouse Mammary Gland*

1990 • 73 citations

ras activity and cyclin D1 expression: An essential mechanism of mouse skin tumor development

1999 • 65 citations

Accumulation of rab4GTP in the Cytoplasm and Association with the Peptidyl-Prolyl Isomerase Pin1 during Mitosis

2000 • 41 citations