Structural and Functional Analysis of the Mitotic Rotamase Pin1 Suggests Substrate Recognition Is Phosphorylation Dependent

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

Proteins: Structures and Molecular Properties

1986 • 2,694 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

A Hot Spot of Binding Energy in a Hormone-Receptor Interface

1995 • 1,943 citations

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1989 • 1,414 citations

Proteins. Structures and molecular properties

1984 • 1,247 citations

Atomic Structures of the Human Immunophilin FKBP-12 Complexes with FK506 and Rapamycin

1993 • 1,202 citations

The MIDAS display system

1988 • 955 citations

Interior and surface of monomeric proteins

1987 • 924 citations

A human peptidyl–prolyl isomerase essential for regulation of mitosis

1996 • 891 citations

The structure of protein-protein recognition sites.

1990 • 825 citations

Mitosis in transition

1994 • 745 citations

Crystal Structure of Human Cyclophilin A Bound to the Amino-Terminal Domain of HIV-1 Capsid

1996 • 697 citations

A fast algorithm for rendering space-filling molecule pictures

1988 • 616 citations

Ordering S phase and M phase in the cell cycle

1994 • 596 citations

Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

1991 • 506 citations

Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide

1996 • 426 citations

A role for surface hydrophobicity in protein‐protein recognition

1994 • 377 citations

Characterization of a novel protein‐binding module — the WW domain

1995 • 365 citations

The cyclophilin homolog ninaA is required in the secretory pathway

1991 • 330 citations

Cyclosporin A slows collagen triple-helix formation in vivo: indirect evidence for a physiologic role of peptidyl-prolyl cis-trans-isomerase.

1991 • 313 citations

The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin.

1994 • 305 citations

Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes

1990 • 303 citations

Structure and function of the WW domain

1996 • 290 citations

Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans

1991 • 243 citations

Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.

1996 • 213 citations

Cyclophilin catalyzes protein folding in yeast mitochondria.

1995 • 191 citations

Evidence for a NIMA-like mitotic pathway in vertebrate cells

1995 • 174 citations

Mechanistic studies of peptidyl prolyl cis-trans isomerase: evidence for catalysis by distortion

1990 • 164 citations

Sequence and mutational analysis of ESS1, a gene essential for growth in Saccharomyces cerevisiae

1989 • 161 citations

Mechanism of Enzymatic and Nonenzymatic Prolyl Cis-Trans Isomerization

1993 • 148 citations

The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclin B: coordination of two mitosis promoting kinases.

1995 • 148 citations

Cyclophilin 20 Is Involved in Mitochondrial Protein Folding in Cooperation with Molecular Chaperones Hsp70 and Hsp60

1995 • 147 citations

A mechanism for rotamase catalysis by the FK506 binding protein (FKBP)

1993 • 147 citations

Algorithm for ribbon models of proteins

1986 • 143 citations

Conic: A fast renderer for spacefilling molecules with shadows

1991 • 139 citations

Substrate specificity for the human rotamase FKBP: a view of FK506 and rapamycin as leucine-(twisted amide)-proline mimics

1990 • 123 citations

The WW module competes with the SH3 domain?

1996 • 112 citations

PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism.

1992 • 105 citations

Protein folding: Prolyl isomerases join the fold

1995 • 95 citations

WW domains

1996 • 84 citations

Properties and regulation of the cell cycle-specific NIMA protein kinase of Aspergillus nidulans.

1993 • 72 citations

Immunosuppressant Target Protein FKBP12 Is Required for P-Glycoprotein Function in Yeast

1996 • 62 citations

Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans.

1994 • 51 citations

Identification of Immunosuppressive Drug Targets in Yeast

1993 • 34 citations

The WW module competes with the SH3 domain?

1996 • 17 citations