The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Mitotic and G ₂ Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

1997 • 1,332 citations

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

1997 • 1,285 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

Uncoupling of Obesity from Insulin Resistance Through a Targeted Mutation in aP2 , the Adipocyte Fatty Acid Binding Protein

1996 • 900 citations

A human peptidyl–prolyl isomerase essential for regulation of mitosis

1996 • 891 citations

cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2

1991 • 870 citations

Sequence-Specific and Phosphorylation-Dependent Proline Isomerization: A Potential Mitotic Regulatory Mechanism

1997 • 762 citations

Cyclin activation of p34cdc2

1990 • 690 citations

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes.

1996 • 685 citations

Structural and Functional Analysis of the Mitotic Rotamase Pin1 Suggests Substrate Recognition Is Phosphorylation Dependent

1997 • 681 citations

Myt1: A Membrane-Associated Inhibitory Kinase That Phosphorylates Cdc2 on Both Threonine-14 and Tyrosine-15

1995 • 658 citations

Monoclonal antibodies to mitotic cells.

1983 • 609 citations

The cdc25 protein contains an intrinsic phosphatase activity

1991 • 595 citations

Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

1991 • 579 citations

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

1997 • 541 citations

Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from Xenopus Egg Extracts

1996 • 506 citations

Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.

1991 • 502 citations

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

1995 • 471 citations

Role of phosphorylation in p34cdc2 activation: identification of an activating kinase.

1992 • 459 citations

Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle.

1995 • 436 citations

Regulation of the cdc25 protein during the cell cycle in Xenopus extracts

1992 • 430 citations

Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: Studies in Xenopus

1990 • 354 citations

The Human Myt1 Kinase Preferentially Phosphorylates Cdc2 on Threonine 14 and Localizes to the Endoplasmic Reticulum and Golgi Complex

1997 • 354 citations

Mitotic induction and maintenance by overexpression of a G2-specific gene that encodes a potential protein kinase

1988 • 324 citations

Cell cycle regulation of a Xenopus Wee1-like kinase.

1995 • 316 citations

Mitotic mutants ofAspergillus nidulans

1975 • 303 citations

Structure and function of the WW domain

1996 • 290 citations

Regulation of the mRNA levels of nimA, a gene required for the G2-M transition in Aspergillus nidulans.

1987 • 288 citations

Cell cycle regulation of human WEE1.

1995 • 281 citations

The decision to enter mitosis

1994 • 270 citations

Plk Is an M-Phase-Specific Protein Kinase and Interacts with a Kinesin-Like Protein, CHO1/MKLP-1

1995 • 266 citations

The cdc25 M-phase inducer: An unconventional protein phosphatase

1992 • 266 citations

Activation of the various cyclin/cdc2 protein kinases

1993 • 253 citations

Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans

1991 • 243 citations

Coupling of mitosis to the completion of S phase in Xenopus occurs via modulation of the tyrosine kinase that phosphorylates p34cdc2

1992 • 231 citations

Casein kinase II is a predominantly nuclear enzyme.

1992 • 208 citations

Confirmation of the existence of a third family among peptidyl‐prolyl cis/trans isomerases Amino acid sequence and recombinant production of parvulin

1994 • 190 citations

Chapter 17 Systems for the Study of Nuclear Assembly, DNA Replication, and Nuclear Breakdown in Xenopus laevis Egg Extracts

1991 • 180 citations

Polo-like Kinase Is a Cell Cycle-regulated Kinase Activated during Mitosis

1995 • 165 citations

Sequence and mutational analysis of ESS1, a gene essential for growth in Saccharomyces cerevisiae

1989 • 161 citations

The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclin B: coordination of two mitosis promoting kinases.

1995 • 148 citations

Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint.

1991 • 135 citations

Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14.

1994 • 129 citations

Cell cycle regulation of the p34cdc2 inhibitory kinases.

1994 • 120 citations

Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity.

1995 • 117 citations

The Drosophila melanogaster dodo (dod) gene, conserved in humans, is functionally interchangeable with the ESS1 cell division gene of Saccharomyces cerevisiae.

1996 • 110 citations

Protein folding: Prolyl isomerases join the fold

1995 • 95 citations

Properties and regulation of the cell cycle-specific NIMA protein kinase of Aspergillus nidulans.

1993 • 72 citations

S-phase, G2, and nuclear division mutants of Aspergillus nidulans

1984 • 68 citations

Vertebrate p34cdc2 phosphorylation site mutants: effects upon cell cycle progression in the fission yeast Schizosaccharomyces pombe

1992 • 41 citations