Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HIV syndrome
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References (67)
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
1972 • 15,349 citations
Hydroperoxide metabolism in mammalian organs.
1979 • 5,821 citations
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
1991 • 4,682 citations
Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.
1991 • 1,505 citations
The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis
1988 • 1,496 citations
J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential
1991 • 1,017 citations
A New Method for the Cytofluorometric Analysis of Mitochondrial Membrane Potential Using the J-Aggregate Forming Lipophilic Cation 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine Iodide (JC-1)
1993 • 1,015 citations
Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes
1995 • 951 citations
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.
1992 • 949 citations
Programmed Death of T Cells in HIV-1 Infection
1992 • 932 citations
Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.
1992 • 907 citations
Transient High Levels of Viremia in Patients with Primary Human Immunodeficiency Virus Type 1 Infection
1991 • 851 citations
Early Treatment of Acute Biliary Pancreatitis by Endoscopic Papillotomy
1993 • 790 citations
SYSTEMIC GLUTATHIONE DEFICIENCY IN SYMPTOM-FREE HIV-SEROPOSITIVE INDIVIDUALS
1989 • 725 citations
High Titers of Cytopathic Virus in Plasma of Patients with Symptomatic Primary HIV-1 Infection
1991 • 697 citations
Infection with HIV is associated with elevated IL-6 levels and production.
1990 • 594 citations
Induction of Apoptosis in Uninfected Lymphocytes by HIV-1 Tat Protein
1995 • 581 citations
Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis
1991 • 548 citations
Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone.
1989 • 544 citations
Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms.
1990 • 529 citations
Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression.
1990 • 471 citations
Control of apoptosis by the cellular ATP level
1996 • 465 citations
Mitochondria are selective targets for the protective effects of heat shock against oxidative injury.
1996 • 407 citations
Localization of endoplasmic reticulum in living and glutaraldehyde-fixed cells with fluorescent dyes
1984 • 384 citations
Cytokine-stimulated human immunodeficiency virus replication is inhibited by N-acetyl-L-cysteine.
1990 • 381 citations
The cytopathic effect of hiv is associated with apoptosis
1991 • 358 citations
Low Concentrations of Acid-Soluble Thiol (Cysteine) in the Blood Plasma of HIV-1-Infected Patients
1989 • 349 citations
A Controlled Trial of Zidovudine in Primary Human Immunodeficiency Virus Infection
1995 • 317 citations
The role of oxidative stress in HIV disease
1995 • 288 citations
Protective Effect of N-Acetylcysteine in Tumor Necrosis Factor-α-Induced Apoptosis in U937 Cells: The Role of Mitochondria
1995 • 274 citations
Tumour necrosis factor-α induces superoxide anion generation in mitochondria of L929 cells
1993 • 272 citations
Inhibition of HIV-1 replication and NF-x B activity by cysteine and cysteine derivatives
1991 • 256 citations
Anergy and apoptosis in CD8+ T cells from HIV-infected persons.
1994 • 252 citations
Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals
1993 • 242 citations
Membrane Expression of HIV Envelope Glycoproteins Triggers Apoptosis in CD4 Cells
1993 • 210 citations
Apoptotic cell death of primed CD45RO+ T lymphocytes in Epstein-Barr virus-induced infectious mononucleosis
1992 • 205 citations
Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals
1993 • 197 citations
Mitochondrial Modifications during Rat Thymocyte Apoptosis: A Study at the Single Cell Level
1994 • 192 citations
N‐Acetylcysteine inhibits apoptosis and decreases viral particles in HIV‐chronically infected U937 cells
1993 • 156 citations
Programmed death of T cells in human immunodeficiency virus infection. No correlation with progression to disease.
1994 • 152 citations
Mitochondrial dysfunctions in circulating T lymphocytes from human immunodeficiency virus-1 carriers [see comments]
1995 • 147 citations
Primary HIV infection
1991 • 145 citations
HIV Causes AIDS
1988 • 139 citations
Diagnosis of Human Immunodeficiency Virus Infection in Seronegative Homosexuals Presenting With an Acute Viral Syndrome
1987 • 117 citations
Tumor necrosis factor-mediated cytotoxicity involves ADP-ribosylation.
1988 • 113 citations
Immunological changes in primary HIV-1 infection
1990 • 104 citations
Massive Activation of Immune Cells with an Intact T Cell Repertoire in Acute Human Immunodeficiency Virus Syndrome
1995 • 69 citations
Serum interleukin-6 concentrations are elevated and associated with elevated tumor necrosis factor-α and immunoglobulin G and A concentrations in children with HIV infection
1991 • 68 citations
Does symptomatic primary HIV-1 infection accelerate progression to CDC stage IV disease, CD4 count below 200 x 106/l, AIDS, and death from AIDS?
1994 • 67 citations
Sendai Virus and Herpes Virus Type 1 Induce Apoptosis in Human Peripheral Blood Mononuclear Cells
1995 • 62 citations
The immunology of primary HIV infection: which immune responses control HIV replication?
1995 • 58 citations
T-cell subset alterations and lymphocyte responsiveness to mitogens and antigen during severe primary infection with HIV
1990 • 58 citations
Effect of aging and acetyl-l-carnitine on energetic and cholinergic metabolism in rat brain regions
1989 • 50 citations
The role of poly(ADP-ribose) synthesis in toxicity and repair of DNA damage
1985 • 44 citations
Mitochondrial Mass and Membrane Potential in Celomocytes from the Earthworm Eisenia foetida: Studies with Fluorescent Probes in Single Intact Cells
1995 • 41 citations
Diagnosis of human immunodeficiency virus infection in seronegative homosexuals presenting with an acute viral syndrome
1987 • 32 citations
Cytokine regulation of human immunodeficiency virus expression
1991 • 27 citations
Cell Death Protection by 3-Aminobenzamide and Other Poly(ADP-Ribose)polymerase Inhibitors: Different Effects on Human Natural Killer and Lymphokine-Activated Killer Cell Activities
1994 • 27 citations
Evidence for dissimilar mechanisms of enhancement of inorganic and organic hydroperoxide cytotoxicity by L-histidine.
1995 • 27 citations
The use of non-radioactive chromium as an alternative to 51Cr in NK assay
1995 • 26 citations
Recovery of Human Lymphocytes Damaged with γ-Radiation or Enzymatically Produced Oxygen Radicals: Different Effects of Poly(ADP-ribosyl)polymerase Inhibitors
1990 • 25 citations
Lack of selective Vβ deletion in CD4+ or CD8+ T lymphocytes and functional integrity of T-cell repertoire during acute HIV syndrome
1995 • 24 citations
Early progression to AIDS following primary HIV infection.
1989 • 23 citations
Programmed cell death and AIDS: significance, perspectives and unanswered questions.
1995 • 23 citations
N-acetylcysteine prevents TNF-induced mitochondrial damage, apoptosis and viral particle production in HIV-infected U937 cells
1994 • 15 citations
Serum thymidine kinase — a marker of bone marrow toxicity during treatment with zidovudine
1989 • 12 citations
Effect of ADP‐Ribosyl Transferase Inhibitors on the Survival of Human Lymphocytes after Exposure to Different DNA‐Damaging Agents a
1988 • 7 citations