Global effects of vitamin A deficiency on gene expression in rat liver: evidence for hypoandrogenism

Basic local alignment search tool

1990 • 87,358 citations

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

Biostatistical Analysis

1996 • 36,713 citations

Statistical significance for genomewide studies

2003 • 9,411 citations

A Direct Approach to False Discovery Rates

2002 • 5,455 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

1998 • 1,954 citations

Orphan Nuclear Receptors: Shifting Endocrinology into Reverse

1999 • 498 citations

Microsomal Ethanol‐Oxidizing System (MEOS): The First 30 Years (1968‐1998)–A Review

1999 • 428 citations

Control of Growth by the Somatropic Axis: Growth Hormone and the Insulin-Like Growth Factors Have Related and Independent Roles

2001 • 377 citations

Cytochrome P450 Nomenclature, 2004

2006 • 269 citations

The Effect of Circulating Growth Hormone-Binding Protein on Metabolic Clearance, Distribution, and Degradation of Human Growth Hormone*

1987 • 220 citations

Expression of the liver-enriched transcriptional activator protein DBP follows a stringent circadian rhythm

1990 • 218 citations

Physiological Substrates for Rat Alcohol Dehydrogenase Classes: Aldehydes of Lipid Peroxidation, ω-Hydroxyfatty Acids, and Retinoids

1993 • 207 citations

Cytochrome P450 Nomenclature

2003 • 205 citations

Regulation of Insulin-like Growth Factor-I in Starvation and Injury

2009 • 159 citations

Starvation response in mouse liver shows strong correlation with life-span-prolonging processes

2004 • 155 citations

Regulation and perturbation of testicular functions by vitamin A

2002 • 145 citations

Sexual Dimorphism of Rat Liver Gene Expression: Regulatory Role of Growth Hormone Revealed by Deoxyribonucleic Acid Microarray Analysis

2003 • 143 citations

Genetic Evidence That Retinaldehyde Dehydrogenase Raldh1 (Aldh1a1) Functions Downstream of Alcohol Dehydrogenase Adh1 in Metabolism of Retinol to Retinoic Acid

2003 • 140 citations

Sex Difference in Hepatic Peroxisome Proliferator-Activated Receptor α Expression: Influence of Pituitary and Gonadal Hormones

2002 • 119 citations

Failure of Insulin-Like Growth Factor-I (IGF-I) Infusion to Promote Growth in Protein-Restricted Rats Despite Normalization of Serum IGF-I Concentrations*

1991 • 112 citations

Regulation of CYP26 (cytochrome P450RAI) mRNA expression and retinoic acid metabolism by retinoids and dietary vitamin A in liver of mice and rats

2000 • 93 citations

Reproducibility of oligonucleotide arrays using small samples

2003 • 85 citations

Structure and Regulation of Rat Liver Microsomal Stearoyl-CoA Desaturase Gene

1990 • 82 citations

Female-Predominant Expression of Fatty Acid Translocase/CD36 in Rat and Human Liver

2003 • 82 citations

Expression of Retinoic Acid Nuclear Receptors and Tissue Transglutaminase Is Altered in Various Tissues of Rats Fed a Vitamin A-Deficient Diet

1992 • 76 citations

Regulation of sulfotransferase mRNA expression in male and female rats of various ages

1998 • 76 citations

Divergent Responses of Serum Insulin-Like Growth Factor-I and Liver Growth Hormone (GH) Receptors to Exogenous GH in Protein-Restricted Rats*

1990 • 67 citations

Mini ReviewRole of Hepatocyte Nuclear Factors in Growth Hormone-regulated, Sexually Dimorphic Expression of Liver Cytochromes P450*

2004 • 63 citations

Mouse Liver CYP2C39 Is a Novel Retinoic Acid 4-Hydroxylase

2004 • 63 citations

INSULIN-LIKE GROWTH FACTOR-1 (IGF-1) IN MICE REDUCES WEIGHT LOSS DURING STARVATION

1989 • 62 citations

Sex-dependent expression and growth hormone regulation of class alpha and class mu glutathione S-transferase mRNAs in adult rat liver

1993 • 61 citations

Cellular retinol-binding protein messenger RNA levels in normal and retinoid-deficient rats.

1990 • 57 citations

Intrinsic signals in the sexually dimorphic circulating growth hormone profiles of the rat

2001 • 56 citations

Senescence Marker Protein-30 (SMP30): Structure and Biological Function

1999 • 55 citations

Large-scale gene profiling of the liver in a mouse model of chronic, intragastric ethanol infusion

2003 • 54 citations

Distributions of retinoids, retinoid‐binding proteins and related parameters in different types of liver cells isolated from young and old rats

1988 • 53 citations

Some novel insights into the pathogenesis of alcoholic steatosis

2004 • 48 citations

Interpulse growth hormone secretion in the episodic plasma profile causes the sex reversal of cytochrome P450s in senescent male rats

2003 • 40 citations

Vitamin A Regulates Genes Involved in Hepatic Gluconeogenesis in Mice: Phosphoenolpyruvate Carboxykinase, Fructose-1,6-bisphosphatase and 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase ,

1997 • 38 citations

Vitamin A exerts its activity at the transcriptional level in the small intestine

2004 • 20 citations

Pretranslational down regulation of cytochrome P450 2C11 in vitamin A-deficient male rat liver: prevention by dietary inclusion of retinoic acid.

1995 • 16 citations

Middle-Age Alterations in the Sexually Dimorphic Plasma Growth Hormone Profiles: Involvement of Growth Hormone-Releasing Factor and Effects on Cytochrome P450 Expression

2002 • 12 citations

Response of the Insulin-Like Growth Factor System to Vitamin A Depletion and Repletion in Rats

2002 • 10 citations

Phospho‐STAT5 accumulation in nuclear fractions from vitamin A‐deficient rat liver

2005 • 10 citations

The Role of Insulin‐Like Growth Factor 1 and Insulin in Ageing and Atherosclerosis

2002 • 10 citations

Effects of vitamin A deficiency on the function of pituitary-gonadal system in male rats.

1989 • 9 citations

Nafenopin-induced peroxisome proliferation in vitamin A deficient rats

1995 • 8 citations

Gene Expression of Cellular Retinol-Binding Protein I (CRBP I) is Affected by Dietary Proteins in the Rat Liver.

1993 • 8 citations

Cell-type specific interactions between retinoic acid and thyroid hormone in the regulation of expression of the gene encoding ornithine aminotransferase.

1995 • 8 citations

Decreased Hepatic Gluconeogenesis in Vitamin A-Deficient Rats

1981 • 7 citations

Effects of Vitamin A Deficiency on Rat Liver Alcohol Dehydrogenase Expression and Alcohol Elimination Rate in Rats

2000 • 4 citations

Metabolic Potential of the Adipose Tissue of Rats during Hyper- and Hypovitaminosis A

1986 • 4 citations

Effects of retinoids on gene expression in different epithelial models in vivo and in vitro.

1998 • 3 citations