Mouse Liver CYP2C39 Is a Novel Retinoic Acid 4-Hydroxylase

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

1996 • 2,895 citations

Polychlorinated Biphenyls (PCBs): Environmental Impact, Biochemical and Toxic Responses, and Implications for Risk Assessment

1994 • 1,717 citations

Immune System Impairment and Hepatic Fibrosis in Mice Lacking the Dioxin-Binding Ah Receptor

1995 • 1,064 citations

Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.

1996 • 887 citations

Benzo[ a ]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

2000 • 623 citations

The AH-receptor: genetics, structure and function

1993 • 437 citations

Interactions of retinoid binding proteins and enzymes in retinoid metabolism

1999 • 410 citations

Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice

2000 • 379 citations

The aryl hydrocarbon receptor: studies using the AHR-null mice.

1998 • 372 citations

Lesions of Aryl-hydrocarbon Receptor–deficient Mice

1997 • 345 citations

CYP26, a Novel Mammalian Cytochrome P450, Is Induced by Retinoic Acid and Defines a New Family

1997 • 299 citations

Retinoids in chemoprevention and differentiation therapy

2000 • 241 citations

Retinoids in chemoprevention and differentiation therapy

2000 • 222 citations

Cloning of a novel retinoic-acid metabolizing cytochrome P450, Cyp26B1, and comparative expression analysis with Cyp26A1 during early murine development

2001 • 217 citations

Cytochrome P450RAI(CYP26) Promoter: A Distinct Composite Retinoic Acid Response Element Underlies the Complex Regulation of Retinoic Acid Metabolism

2000 • 209 citations

Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

2000 • 163 citations

The Involvement of Aryl Hydrocarbon Receptor in the Activation of Transforming Growth Factor-β and Apoptosis

1998 • 154 citations

Cyp26C1 encodes a novel retinoic acid-metabolizing enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine development

2003 • 147 citations

Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation

2000 • 139 citations

Aryl hydrocarbon receptor knockout mice (AHR-/-) exhibit liver retinoid accumulation and reduced retinoic acid metabolism.

1997 • 133 citations

Cloning and Expression of Murine CYP2Cs and Their Ability to Metabolize Arachidonic Acid

1998 • 109 citations

An additional defective allele, CYP2C19*5, contributes to the S-mephenytoin poor metabolizer phenotype in Caucasians

1998 • 100 citations

Feedback Inhibition of the Retinaldehyde Dehydrogenase GeneALDH1 by Retinoic Acid through Retinoic Acid Receptor α and CCAAT/Enhancer-binding Protein β

2000 • 90 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Diverse Retinoic Acid Metabolites in Multiple Tissues of the Sprague-Dawley Rat

1995 • 28 citations