Intrinsic signals in the sexually dimorphic circulating growth hormone profiles of the rat

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1996 • 309 citations

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1985 • 261 citations

Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450.

1991 • 255 citations

Gender differences in drug metabolism regulated by growth hormone

1995 • 227 citations

Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion.

1992 • 140 citations

Hepatic steroid hydroxylating enzymes are controlled by the sexually dimorphic pattern of growth hormone secretion in normal and dwarf rats

1992 • 139 citations

Adult male-specific and neonatally programmed rat hepatic P-450 forms RLM2 and 2a are not dependent on pulsatile plasma growth hormone for expression.

1988 • 138 citations

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1995 • 106 citations

Pituitary Regulation of the Male-Specific Steroid 6β-Hydroxylase P-450 2a (gene product IIIA2) in Adult Rat Liver. Suppressive Influence of Growth Hormone and Thyroxine Acting at a Pretranslational Level

1990 • 86 citations

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1993 • 86 citations

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1992 • 83 citations

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1992 • 79 citations

Signalling Elements in the Ultradian Rhythm of Circulating Growth Hormone Regulating Expression of Sex-Dependent Forms of Hepatic Cytochrome P450*

1989 • 70 citations

Differential expression of gender-dependent hepatic isoforms of cytochrome P-450 by pulse signals in the circulating masculine episodic growth hormone profile of the rat.

2000 • 69 citations

Gender Differences in the Responsiveness of the Sex-Dependent Isoforms of Hepatic P450 to the Feminine Plasma Growth Hormone Profile¹

1999 • 68 citations

[24] Rat hepatic P450IIA and P450IIC subfamily expression using catalytic, immunochemical, and molecular probes

1991 • 63 citations

Feminization of hepatic cytochrome P450s by nominal levels of growth hormone in the feminine plasma profile.

1996 • 58 citations

Pretranslational control by thyroid hormone of rat liver steroid 5 alpha-reductase and comparison to the thyroid dependence of two growth hormone-regulated CYP2C mRNAs.

1990 • 58 citations

Hepatic P450 Expression in Hypothyroid Rats: Differential Responsiveness of Male-Specific P450 Forms 2a (IIIA2), 2c (IIC11), and RLM2 (IIA2) to Thyroid Hormone

1991 • 55 citations

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1996 • 53 citations

Repetitive blood sampling in unrestrained and unstressed mice using a chronic indwelling right atrial catheterization apparatus.

1988 • 50 citations

Steroid metabolism by constitutive cytochromes P450

1992 • 48 citations

Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion

1992 • 45 citations

Dilution of the chemiluminescence reagents reduces the background noise on western blots.

1995 • 45 citations

Growth hormone regulation of the cytochrome P-450IIC subfamily in the rat: inductive, repressive, and transcriptional effects on P-450f (IIC7) and P-450PB1 (IIC6) gene expression.

1990 • 43 citations

Growth Hormone-Dependent and -Independent Sexually Dimorphic Regulation of Phenobarbital-Induced Hepatic Cytochrome P450 2B1 and -2B2

1994 • 40 citations

Renaturalizing the sexually dimorphic profiles of circulating growth hormone in hypophysectomized rats

1991 • 35 citations

Hormonal Regulation of Levels of the Messenger RNA Encoding Hepatic P450 2c (IIC11), a Constitutive Male-Specific Form of Cytochrome P450

1990 • 35 citations

Depletion of Serum Growth Hormone in Adult Female Rats by Neonatal Monosodium Glutamate Treatment without Loss of Female-Specific Hepatic Enzymes P450 2d (IIC12) and Steroid 5α-Reductase*

1990 • 33 citations

Gender Differences in the Responsiveness of the Sex-Dependent Isoforms of Hepatic P450 to the Feminine Plasma Growth Hormone Profile

1999 • 32 citations

Irreversible suppression of growth hormone-dependent cytochrome P450 2C11 in adult rats neonatally treated with monosodium glutamate.

1993 • 31 citations

Modulation of Hepatic Level of Microsomal Testosterone 7α-Hydroxylase, P-450a (P450IIA), by Thyroid Hormone and Growth Hormone in Rat Liver1

1990 • 30 citations

Thin-Layer Chromatographic Separation of Regioselective and Stereospecific Androgen Metabolites

1995 • 27 citations

Infusion of gender-dependent plasma growth hormone profiles into intact rats: effects of subcutaneous, intraperitoneal, and intravenous routes of rat and human growth hormone on endogenous circulating growth hormone profiles and expression of sexually dimorphic hepatic cyp isoforms.

2001 • 27 citations

Androgenic repression of hexobarbitone metabolism and action in Crl:CD‐1 (ICR)BR mice

1984 • 27 citations

Over-expression of CYP2C11, the major male-specific form of hepatic cytochrome P450, in the presence of nominal pulses of circulating growth hormone in adult male rats neonatally exposed to low levels of monosodium glutamate.

1994 • 22 citations

Serum Thyrotropin Concentrations Are More Highly Correlated with Serum Triiodothyronine Concentrations than with Serum Thyroxine Concentrations in Thyroid Hormone-Infused Thyroidectomized Rats*

1989 • 21 citations

Subnormal concentrations in the feminine profile of circulating growth hormone enhance expression of female-specific CYP2C12

1994 • 16 citations

Nominal Growth Hormone Pulses in Otherwise Normal Masculine Plasma Profiles Induce Intron Retention of Overexpressed Hepatic CYP2C11 with Associated Nuclear Splicing Deficiency**This work was supported by NIH Grants GM-45758 and HD-16358.

2000 • 11 citations