Sex Difference in Hepatic Peroxisome Proliferator-Activated Receptor α Expression: Influence of Pituitary and Gonadal Hormones

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*

1999 • 2,880 citations

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat.

1996 • 2,130 citations

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

1997 • 2,105 citations

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

1997 • 2,100 citations

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

1992 • 1,751 citations

Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

1999 • 1,589 citations

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism

1999 • 1,260 citations

Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression

1996 • 1,201 citations

Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay

1997 • 1,158 citations

The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation

1996 • 1,036 citations

A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders

1999 • 931 citations

P<scp>EROXISOMAL</scp>β-O<scp>XIDATION AND</scp>P<scp>EROXISOME</scp>P<scp>ROLIFERATOR</scp>–A<scp>CTIVATED</scp>R<scp>ECEPTOR</scp>α: An Adaptive Metabolic System

2001 • 896 citations

Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor.

1992 • 863 citations

Age- and Sex-Related Differences in Episodic Growth Hormone Secretion in the Rat*

1979 • 543 citations

Rat PPARs: Quantitative Analysis in Adult Rat Tissues and Regulation in Fasting and Refeeding

2001 • 463 citations

Peroxisome proliferator activated receptor-alpha expression in human liver.

1998 • 449 citations

Differential Expression of Peroxisome Proliferator-Activated Receptor-α, -β, and -γ during Rat Embryonic Development*

1998 • 423 citations

A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice.

1998 • 407 citations

Peroxisome Proliferator Activated Receptor-α Expression in Human Liver

1998 • 397 citations

Expression of the Peroxisome Proliferator-activated Receptor α Gene Is Stimulated by Stress and Follows a Diurnal Rhythm

1996 • 317 citations

Ligand Selectivity of the Peroxisome Proliferator-Activated Receptor α

1998 • 266 citations

Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450.

1991 • 255 citations

Regulation of the peroxisome proliferator-activated receptor alpha gene by glucocorticoids.

1994 • 227 citations

The Acute Phase Response Is Associated with Retinoid X Receptor Repression in Rodent Liver

2000 • 225 citations

The Effect of Peroxisome Prouferators on Microsomal. Peroxisomal, and Mitochondrial Enzyme Activities in the Liver and Kidney

1987 • 211 citations

Sex-dependent expression and clofibrate inducibility of cytochrome P450 4A fatty acid omega-hydroxylases. Male specificity of liver and kidney CYP4A2 mRNA and tissue-specific regulation by growth hormone and testosterone.

1992 • 207 citations

Influence of Gonadal Steroids on Age- and Sex-Related Secretory Patterns of Growth Hormone in the Rat^*

1984 • 184 citations

Association between Plasma Level of Growth Hormone and Sex Differentiation of Hepatic Steroid Metabolism in the Rat*

1982 • 171 citations

Continuous Infusion of Growth Hormone Feminizes Hepatic Steroid Metabolism in the Rat*

1981 • 156 citations

Peroxisome Proliferator‐activated Receptors: Stuctures and Function

1996 • 151 citations

Dexamethasone and Insulin Demonstrate Marked and Opposite Regulation of the Steady‐State mRNA Level of the Peroxisomal Proliferator‐Activated Receptor (PPAR) in Hepatic Cells

1994 • 143 citations

Hepatic steroid hydroxylating enzymes are controlled by the sexually dimorphic pattern of growth hormone secretion in normal and dwarf rats

1992 • 139 citations

Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver

1992 • 110 citations

Microarray Analysis of the in Vivo Effects of Hypophysectomy and Growth Hormone Treatment on Gene Expression in the Rat*

2001 • 105 citations

MICROBODIES IN EXPERIMENTALLY ALTERED CELLS

1969 • 101 citations

TNF‐α downregulates the peroxisome proliferator activated receptor‐α and the mRNAs encoding peroxisomal proteins in rat liver

1997 • 100 citations

Characteristics of dehydroepiandrosterone as a peroxisome proliferator

1991 • 98 citations

Quantitative Microscopy Comparison of Peroxisome Proliferation by the Lipid-Regulating Agent Gemfibrozil in Several Species

1984 • 96 citations

Differential Effects of Continuous Versus Intermittent Administration of Growth Hormone to Hypophysectomized Female Rats on Serum Lipoproteins and Their Apoproteins*

1989 • 72 citations

PPARα deficiency increases secretion and serum levels of apolipoprotein B-containing lipoproteins

2001 • 72 citations

Alcohol consumption enhances fatty acid ω-oxidation, with a greater increase in male than in female rats

1993 • 72 citations

Sex-related difference in the inductions by perfluoro-octanoic acid of peroxisomal β-oxidation, microsomal 1-acylglycerophosphocholine acyltransferase and cytosolic long-chain acyl-CoA hydrolase in rat liver

1989 • 66 citations

Effects of growth hormone on apolipoprotein-B (apoB) messenger ribonucleic acid editing, and apoB 48 and apoB 100 synthesis and secretion in the rat liver.

1992 • 63 citations

Biphasic Effects of the Natural Estrogen 17β-Estradiol on Hepatic Cholesterol Metabolism in Intact Female Rats

2000 • 63 citations

Sex-dependent regulation of hepatic peroxisome proliferation in mice by trichloroethylene via peroxisome proliferator-activated receptor (PPAR )

2000 • 55 citations

Sex-related differences in the enhancing effects of perfluoro-octanoic acid on stearoyl-CoA desaturase and its influence on the acyl composition of phospholipid in rat liver. Comparison with clofibric acid and tiadenol

1989 • 45 citations

Regulation of sexually dimorphic hepatic steroid metabolism by the somatostatin-growth hormone axis

1983 • 41 citations

Mode of growth hormone administration influences triacylglycerol synthesis and assembly of apolipoprotein B-containing lipoproteins in cultured rat hepatocytes

1996 • 36 citations

Effects of fatty acids and growth hormone on liver fatty acid binding protein and PPARα in rat liver

2001 • 35 citations

Peroxisome proliferator-activated receptor-α expressionin rat liver during postnatal development

2000 • 34 citations

Gender differences in medium-chain dicarboxylic aciduria in alcoholic men and women

1999 • 32 citations

Effects of testosterone, hypophysectomy and growth hormone treatment on clofibrate induction of peroxisomal β-oxidation in female rat liver

1994 • 26 citations

Suppressive effect of growth hormone on the expression of peroxisome proliferator-activated receptor in cultured rat hepatocytes.

1995 • 25 citations

Sex differences in fatty acid composition of rat liver phosphatidylcholine are regulated by the plasma pattern of growth hormone

1988 • 25 citations

The influence of gonadal steroids and the pituitary on the levels and composition of plasma phospholipids in the rat

1987 • 17 citations