A Heterotrimeric G i3-protein Controls Autophagic Sequestration in the Human Colon Cancer Cell Line HT-29

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

1982 • 1,313 citations

INHIBITORS OF THE BIOSYNTHESIS AND PROCESSING OF N-LINKED OLIGOSACCHARIDE CHAINS

1987 • 1,122 citations

G Proteins: A Family of Signal Transducers

1986 • 975 citations

Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

1992 • 741 citations

Autophagy and related mechanisms of lysosome-mediated protein degradation

1994 • 506 citations

Autophagy and other vacuolar protein degradation mechanisms

1992 • 408 citations

Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies.

1989 • 374 citations

Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan.

1988 • 335 citations

A heterotrimeric G protein, G alpha i-3, on Golgi membranes regulates the secretion of a heparan sulfate proteoglycan in LLC-PK1 epithelial cells.

1991 • 304 citations

Stepwise assembly of functionally active transport vesicles

1993 • 298 citations

Mechanism and regulation of protein degradation in liver

1989 • 220 citations

Role of heterotrimeric G proteins in membrane traffic.

1992 • 206 citations

Regulation of apical transport in epithelial cells by a Gsclass of heterotrimeric G protein

1993 • 188 citations

Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis.

1993 • 188 citations

Dependence of hepatocytic autophagy on intracellularly sequestered calcium.

1993 • 173 citations

Dipeptidyl peptidase IV (CD 26) gene expression in enterocyte-like colon cancer cell lines HT-29 and Caco-2. Cloning of the complete human coding sequence and changes of dipeptidyl peptidase IV mRNA levels during cell differentiation.

1992 • 171 citations

The intracellular accumulation of UDP-N-acetylhexosamines is concomitant with the inability of human colon cancer cells to differentiate.

1985 • 168 citations

Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily

1993 • 146 citations

Multiple GTP-binding proteins regulate vesicular transport from the ER to Golgi membranes.

1992 • 123 citations

FITC-dextran as a probe for endosome function and localization in kidney

1990 • 112 citations

Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a metallothionein-alpha i-2 fusion gene in LLC-PK1 cells.

1990 • 112 citations

Inhibition of hepatocytic autophagy by okadaic acid and other protein phosphatase inhibitors

1993 • 87 citations

Cellular variations in heterotrimeric G protein localization and expression in rat pituitary.

1994 • 83 citations

Sequential transport of protein between the endoplasmic reticulum and successive Golgi compartments in semi-intact cells

1991 • 67 citations

Identification of a G protein in rough endoplasmic reticulum of canine pancreas.

1988 • 62 citations

The processing of asparagine-linked oligosaccharides in HT-29 cells is a function of their state of enterocytic differentiation. An accumulation of Man9,8-GlcNAc2-Asn species is indicative of an impaired N-glycan trimming in undifferentiated cells.

1988 • 55 citations

Use of [3H]raffinose as a specific probe of autophagic sequestration

1986 • 48 citations

Pathology of Cell Membranes

1977 • 39 citations

De novo autophagic vacuole formation in hepatocytes permeabilized by Staphylococcus aureus alpha-toxin. Inhibition by nonhydrolyzable GTP analogs.

1994 • 32 citations

Interferon-γ modulates cAMP-induced mucin exocytosis without affecting mucin gene expression in a human colonic goblet cell line

1994 • 32 citations

Autophagic Degradation of N-Linked Glycoproteins Is Downregulated in Differentiated Human Colon Adenocarcinoma Cells

1993 • 27 citations

Asymmetrical distribution of G-proteins among the apical and basolateral membranes of rat enterocytes

1991 • 26 citations

High level expression of transfected G protein α_i3 subunit is required for plasma membrane targeting and adenylyl cyclase inhibition in NIH 3T3 fibroblasts

1992 • 22 citations

The N-glycan processing in HT-29 cells is a function of their state of enterocytic differentiation. Evidence for an atypical traffic associated with change in polypeptide stability in undifferentiated HT-29 cells.

1991 • 18 citations

Gs and Gi protein subunits during cell differentiation in intestinal crypt-villus axis: regulation at the mRNA level

1992 • 16 citations