The intracellular accumulation of UDP-N-acetylhexosamines is concomitant with the inability of human colon cancer cells to differentiate.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

1977 • 1,556 citations

A fine-structure genetic and chemical study of the enzyme alkaline phosphatase of E. Coli I. Purification and characterization of alkaline phosphatase

1960 • 1,407 citations

Synthesis and Processing of Asparagine-Linked Oligosaccharides

1981 • 1,403 citations

Hemoglobin Synthesis in Murine Virus-Induced Leukemic Cells In Vitro: Stimulation of Erythroid Differentiation by Dimethyl Sulfoxide

1971 • 1,371 citations

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

1979 • 1,228 citations

Purification of the human intestinal brush border membrane

1973 • 799 citations

Human Tumor Cells in Vitro

1975 • 753 citations

Butyric acid, a potent inducer of erythroid differentiation in cultured erythroleukemic cells

1975 • 663 citations

The biochemistry of glycoproteins and proteoglycans

1980 • 651 citations

An Analytical System for Rapid Separation of Tissue Nucleotides at Low Pressures on Conventional Anion Exchangers

1975 • 534 citations

The aminopeptidase from hog intestinal brush border

1973 • 529 citations

Topology of microvillar membrance hydrolases of kidney and intestine.

1982 • 437 citations

A one-step ultramicro method for the assay of intestinal disaccharidases

1966 • 420 citations

Enterocytic differentiation of a subpopulation of the human colon tumor cell line HT‐29 selected for growth in sugar‐free medium and its inhibition by glucose

1985 • 343 citations

THE FEEDBACK CONTROL OF SUGAR NUCLEOTIDE BIOSYNTHESIS IN LIVER

1964 • 310 citations

Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells

1980 • 237 citations

Paper Chromatography of Phosphoric Esters

1952 • 233 citations

URIDINE DIPHOSPHATE ACETYLGLUCOSAMINE

1953 • 228 citations

The Utilization of Carbohydrates by Human Cell Cultures

1958 • 206 citations

High-pressure liquid chromatography-ultraviolet analysis of intracellular nucleotides

1982 • 155 citations

The continuous growth of vertebrate cells in the absence of sugar.

1981 • 114 citations

High-molecular-weight glycoproteins are the major carriers of the carbohydrate differentiation antigens I, i and SSEA-1 of mouse teratocarcinoma cells

1983 • 109 citations

[29] Phosphodiesterases

1963 • 107 citations

Alkaline phosphatase in HT-29, a human colon cancer cell line: Influence of sodium butyrate and hyperosmolality

1981 • 97 citations

Butyric acid suppression of the in vitro neoplastic state of Syrian hamster cells

1978 • 76 citations

N,N-Dimethylformamide-induced morphological differentiation and reduction of tumorigenicity in cultured mouse rhabdomyosarcoma cells.

1977 • 69 citations

Maturation-induction of tumor cells using a human colon carcinoma model

1980 • 62 citations

Hexamethylene bisacetamide induces morphologic changes and increased synthesis of procollagen in cell line from glioblastoma multiforme.

1977 • 61 citations

Biological activities of isolated tunicamycin and streptovirudin fractions

1981 • 47 citations

Effect of simple sugars on the morphology and growth pattern of mammalian cell cultures.

1965 • 43 citations

Separation of sugar phosphates and sugar nucleotides by thin-layer chromatography

1964 • 43 citations

<scp>d</scp>-glucosamine-induced changes in nucleotide metabolism and growth of colon-carcinoma cells in culture

1984 • 39 citations

The biochemical and ultrastructural effects of tunicamycin and D‐glucosamine in L1210 leukemic cells

1983 • 38 citations

Ribose-1-P is the essential precursor for nucleic acid synthesis in animal cells growing on uridine in the absence of sugar.

1982 • 33 citations

Biochemical effects and therapeutic potential of tunicamycin in murine L1210 leukemia.

1983 • 32 citations

Separation and analysis of 4′-epimeric UDP-sugars by borate high-performance liquid chromatography

1983 • 31 citations

Role of glycoproteins in neuronal differentiation

1983 • 27 citations

Modifications of mammalian cell surfaces induced by sugars: Scanning electron microscopy

1976 • 27 citations

Sugar-free growth of mammalian cells on some ribonucleosides but not on others.

1983 • 21 citations

Cell surface carbohydrate chemistry

1979 • 20 citations

Evidence indicating that UDP-N-acetylglucosamine does not appear to stimulate hepatic microsomal UDP-glucuronosyltransferase by interaction with the catalytic unit of the enzyme

1983 • 15 citations