Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a metallothionein-alpha i-2 fusion gene in LLC-PK1 cells.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium.

1987 • 751 citations

Do GTPases direct membrane traffic in secretion?

1988 • 540 citations

Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies.

1989 • 374 citations

The G protein-gated atrial K+ channel is stimulated by three distinct GIα-subunits

1988 • 306 citations

G protein multiplicity in eukaryotic signal transduction systems

1988 • 267 citations

Splice Variants of the α Subunit of the G Protein G _s Activate Both Adenylyl Cyclase and Calcium Channels

1989 • 225 citations

Signal transduction by G proteins

1990 • 159 citations

Recombinant Fragment of Protein Kinase Inhibitor Blocks Cyclic AMP-Dependent Gene Transcription

1987 • 139 citations

Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice

1985 • 108 citations

G Protein Subunit, αi-3, Activates a Pertussis Toxin-Sensitive Na+ Channel from the Epithelial Cell Line, A6

1989 • 96 citations

Inhibition of epithelial Na+ transport by atriopeptin, protein kinase c, and pertussis toxin

1987 • 55 citations

Relationship of (8-lysine) vasopressin receptor transition to receptor functional properties in a pig kidney cell line (LLC-PK1).

1981 • 55 citations

Tissue-specific regulation of GTP-binding protein and muscarinic acetylcholine receptor levels during cardiac development

1987 • 52 citations

Cross talk between stimulatory and inhibitory guanosine 5'-triphosphate binding proteins: role in activation and desensitization of the adenylate cyclase response to vasopressin

1987 • 29 citations

Provasopressin-neurophysin II processing is cell-specific in heterologous cell lines expressing a metallothionein-vasopressin fusion gene.

1987 • 28 citations

Tissue- and species-specific expression of inhibitory guanine nucleotide-binding proteins. Cloning of a full-length complementary DNA from canine heart.

1989 • 26 citations

Conductive Na+ transport in an epithelial cell line (LLC-PK1) with characteristics of proximal tubular cells

1987 • 19 citations

Mechanisms of nonhormonal activation of adenylate cyclase based on target analysis

1986 • 12 citations