CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming

Innate Immune Recognition

2002 • 8,157 citations

The Danger Model: A Renewed Sense of Self

2002 • 4,107 citations

Getting to the site of inflammation: the leukocyte adhesion cascade updated

2007 • 3,957 citations

Tolerogenic Dendritic Cells

2003 • 3,131 citations

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1998 • 2,106 citations

Taking dendritic cells into medicine

2007 • 2,044 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

2001 • 1,845 citations

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1998 • 1,546 citations

Defective TCR expression in transgenic mice constructed using cDNA‐based α‐ and β‐chain genes under the control of heterologous regulatory elements

1998 • 1,460 citations

Efficient Targeting of Protein Antigen to the Dendritic Cell Receptor DEC-205 in the Steady State Leads to Antigen Presentation on Major Histocompatibility Complex Class I Products and Peripheral CD8+ T Cell Tolerance

2002 • 1,296 citations

Induced recruitment of NK cells to lymph nodes provides IFN-γ for TH1 priming

2004 • 1,284 citations

Homing and cellular traffic in lymph nodes

2003 • 1,233 citations

Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance

2002 • 1,176 citations

Dendritic cells in a mature age

2006 • 1,147 citations

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells

2005 • 1,142 citations

The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation

1994 • 1,099 citations

Visualizing the generation of memory CD4 T cells in the whole body

2001 • 1,029 citations

Regulation of Dendritic Cell Migration to the Draining Lymph Node

2003 • 863 citations

Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells

1997 • 719 citations

The inflammasome: a danger sensing complex triggering innate immunity

2007 • 683 citations

CD40/CD154 Interactions at the Interface of Tolerance and Immunity

2004 • 673 citations

Th17: the third member of the effector T cell trilogy

2007 • 642 citations

Perspectives series: cell adhesion in vascular biology. Role of PSGL-1 binding to selectins in leukocyte recruitment.

1997 • 620 citations

CD40 Triggering of Heterodimeric IL-12 p70 Production by Dendritic Cells In Vivo Requires a Microbial Priming Signal

2000 • 558 citations

Visualization of Gene Expression in Living Adult Drosophila

1996 • 535 citations

Role of PSGL-1 binding to selectins in leukocyte recruitment.

1997 • 491 citations

Inaugural Article : avoiding horror autotoxicus. The importance of dendritic cells in peripheral T cell tolerance

2002 • 448 citations

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor.

1994 • 418 citations

Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.

1995 • 393 citations

Increased interleukin 12 production in progressive multiple sclerosis: Induction by activated CD4⁺T cells via CD40 ligand

1997 • 313 citations

Platelet-Mediated Lymphocyte Delivery to High Endothelial Venules

1996 • 305 citations

CD4+ T Cell Tolerance to Parenchymal Self-Antigens Requires Presentation by Bone Marrow–derived Antigen-presenting Cells

1998 • 300 citations

Effects of fluid dynamic forces on vascular cell adhesion.

1996 • 263 citations

A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex.

1995 • 231 citations

Phenotypic and Functional Analysis of Cd8+ T Cells Undergoing Peripheral Deletion in Response to Cross-Presentation of Self-Antigen

2001 • 220 citations

L-selectin-negative CCR7− effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells

2007 • 201 citations

Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease

2004 • 198 citations

Flow Cytometry and Cell Sorting

2007 • 187 citations

Migration and Function of Antigen-Primed Nonpolarized T Lymphocytes in Vivo

2001 • 176 citations

Lymphoid reservoirs of antigen-specific memory T helper cells

2007 • 172 citations

E- and P-Selectin Are Not Involved in the Recruitment of Inflammatory Cells Across the Blood-Brain Barrier in Experimental Autoimmune Encephalomyelitis

1997 • 171 citations

Innate control of adaptive immunity via remodeling of lymph node feed arteriole

2005 • 146 citations

Highways, byways and breadcrumbs: directing lymphocyte traffic in the lymph node

2007 • 138 citations

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity

2008 • 123 citations

The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches.

1998 • 99 citations

Myeloma based expression system for production of large mammalian proteins

1991 • 97 citations

Naive CD4 T cells constitutively express CD40L and augment autoreactive B cell survival

2006 • 89 citations

Preformed CD40 ligand exists in secretory lysosomes in effector and memory CD4+ T cells and is quickly expressed on the cell surface in an antigen-specific manner

2007 • 81 citations

The Roles of L-Selectin, β7 Integrins, and P-Selectin in Leukocyte Rolling and Adhesion in High Endothelial Venules of Peyer’s Patches

1998 • 78 citations

Lipopolysaccharide Injection Induces Relapses of Experimental Autoimmune Encephalomyelitis in Nontransgenic Mice via Bystander Activation of Autoreactive CD4+ Cells

2005 • 75 citations

Helper Requirements for Generation of Effector CTL to Islet β Cell Antigens

2004 • 61 citations

Elevated CD40 Ligand Expressing Blood T‐Cell Levels in Multiple Sclerosis Are Reversed by Interferon‐Beta Treatment

2000 • 56 citations

Increased T cell expression of CD154 (CD40‐ligand) in multiple sclerosis

2001 • 40 citations

Expression of E-Selectin, P-Selectin, and Intercellular Adhesion Molecule-1 during Experimental Murine Listeriosis

1999 • 39 citations

CD4+ T Lymphocytes with Constitutive CD40 Ligand in Preautoimmune (NZB × NZW)F1 Lupus-Prone Mice: Phenotype and Possible Role in Autoreactivity

2000 • 32 citations

Immunotherapy Targeting the CD40/CD154 Costimulatory Pathway for Treatment of Autoimmune Disease

2004 • 29 citations

P-selectin glycoprotein ligand-1 mediates L-selectin-independent leukocyte rolling in high endothelial venules of peripheral lymph nodes

2007 • 17 citations

Activated Lymph Nodes Recruit Blood Borne NK Cells and Effector T Cells:Implications for Adaptive T Cell Responses

2008 • 2 citations