Elevated CD40 Ligand Expressing Blood T‐Cell Levels in Multiple Sclerosis Are Reversed by Interferon‐Beta Treatment

Rating neurologic impairment in multiple sclerosis

1983 • 14,011 citations

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by Listeria -Induced Macrophages

1993 • 3,140 citations

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

1992 • 1,846 citations

Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

1995 • 1,528 citations

The CD40 Antigen and its Ligand

1994 • 1,259 citations

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.

1993 • 991 citations

Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production.

1996 • 516 citations

CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis.

1996 • 492 citations

CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.

1995 • 481 citations

The Role of CD40 Ligand in Costimulation and T‐Cell Activation

1996 • 441 citations

Requirement for CD40 Ligand in Costimulation Induction, T Cell Activation, and Experimental Allergic Encephalomyelitis

1996 • 425 citations

Expression of functional CD40 by vascular endothelial cells.

1995 • 414 citations

Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes.

1996 • 360 citations

A central role of CD40 ligand in the regulation of CD4+ T-cell responses

1996 • 329 citations

Increased interleukin 12 production in progressive multiple sclerosis: Induction by activated CD4⁺T cells via CD40 ligand

1997 • 313 citations

Interferon β decreases T cell activation and interferon γ production in multiple sclerosis

1993 • 264 citations

The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells

1998 • 230 citations

Functional CD40 ligand is expressed by T cells in rheumatoid arthritis.

1997 • 166 citations

Regulation of expression of the ligand for CD40 on T helper lymphocytes.

1993 • 155 citations

Recombinant Interferon-β blocks proliferation but enhances interleukin-10 secretion by activated human T-cells

1996 • 122 citations

In vitro and in vivo inhibition of mitogen‐driven T‐cell activation by recombinant interferon beta

1993 • 91 citations

The role of CD40-CD40 ligand interaction in human T cell-B cell collaboration.

1994 • 85 citations

Interferon β-1b effects on cytokine mRNA in peripheral mononuclear cells in multiple sclerosis

1996 • 57 citations

Viruses and multiple sclerosis

1997 • 52 citations

Type I interferons (IFN-α and -β) suppress cytotoxin (tumor necrosis factor-α and lymphotoxin) production by mitogen-stimulated human peripheral blood mononuclear cells

1992 • 51 citations

Activation of antigen-enriched b cells. I. Purification and response to thymus-independent antigens.

1983 • 50 citations

Monocyte Inducible Nitric Oxide Synthase in Multiple Sclerosis: Regulatory Role of Nitric Oxide

1997 • 44 citations

Monocyte activation in multiple sclerosis

1998 • 43 citations

Clinical Trial of Natural Alpha Interferon in Multiple Sclerosis^a

1984 • 18 citations

Viruses and Autoimmune Diseases

1997 • 14 citations

Biologic effects of interferons: relevance to multiple sclerosis.

1995 • 7 citations