Transgenic expression of CD40 ligand produces an in vivo antitumor immune response against both CD40+ and CD40− plasmacytoma cells

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

A PROSPECTIVE, RANDOMIZED TRIAL OF AUTOLOGOUS BONE MARROW TRANSPLANTATION AND CHEMOTHERAPY IN MULTIPLE MYELOMA

2013 • 2,176 citations

CD40-CD40 ligand

2000 • 1,376 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

The Central Role of CD4+ T Cells in the Antitumor Immune Response

1998 • 1,332 citations

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

1994 • 1,185 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells.

1992 • 818 citations

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal.

1993 • 622 citations

Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

1998 • 586 citations

Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by Ex Vivo Granulocyte-Macrophage Colony-Stimulating Factor Gene Transfer

1998 • 419 citations

Idiotype Vaccination Using Dendritic Cells After Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma—A Feasibility Study

1999 • 398 citations

The Intracisternal A-Particle Gene Family: Structure and Functional Aspects

1988 • 341 citations

Impact on survival of high-dose therapy with autologous stem cell support in patients younger than 60 years with newly diagnosed multiple myeloma: a population-based study

2000 • 317 citations

DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma

1998 • 303 citations

Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells.

1998 • 247 citations

Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity.

1995 • 224 citations

Generation of tumor-specific T-lymphocytes by cross-priming with human dendritic cells ingesting apoptotic tumor cells.

2000 • 222 citations

Expression of CD28 and CD40 in human myeloma cells: a comparative study with normal plasma cells

1994 • 220 citations

Autoimmune-Like Antibodies to the Ligand-Binding Sites of Myeloma Proteins

1971 • 213 citations

Genes encoding tumor-specific antigens are expressed in human myeloma cells

1999 • 201 citations

Idiotype Vaccination in Human Myeloma: Generation of Tumor-Specific Immune Responses After High-Dose Chemotherapy

1999 • 150 citations

Tumor Immunology

1998 • 146 citations

CD40 Ligand Induces an Antileukemia Immune Response In Vivo

1997 • 142 citations

Ex Vivo Generation of Human Anti–Pre-B Leukemia-Specific Autologous Cytolytic T Cells

1997 • 131 citations

Muc-1 Core Protein Is Expressed on Multiple Myeloma Cells and Is Induced by Dexamethasone

1999 • 129 citations

Idiotype-reactive T-cell subsets and tumor load in monoclonal gammopathies

1995 • 117 citations

Tumor-specific recognition of human myeloma cells by idiotype-induced CD8+ T cells

2000 • 114 citations

IL-2 Adenovector-Transduced Autologous Tumor Cells Induce Antitumor Immune Responses in Patients With Neuroblastoma

1998 • 106 citations

IL-2 Adenovector-Transduced Autologous Tumor Cells Induce Antitumor Immune Responses in Patients With Neuroblastoma

1998 • 99 citations

Membrane-bound CD154, but not CD40-specific antibody, mediates NF-κB-independent IL-6 production in B cells

1999 • 92 citations

Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells.

1998 • 76 citations

Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by Ex Vivo Granulocyte-Macrophage Colony-Stimulating Factor Gene Transfer

1998 • 71 citations

Activated idiotype-reactive cells in suppressor/cytotoxic subpopulations of monoclonal gammopathies: correlation with diagnosis and disease status

1988 • 66 citations

Antitumor Responses Induced by Transgenic Expression of CD40 Ligand

1997 • 66 citations

CD11a-CD18 and CD102 interactions mediate human myeloma cell growth arrest induced by CD40 stimulation.

1996 • 55 citations

Cell‐based vaccines for the stimulation of immunity to metastatic cancers

1999 • 55 citations

Activated idiotype-reactive cells in suppressor/cytotoxic subpopulations of monoclonal gammopathies: correlation with diagnosis and disease status

1988 • 49 citations

CD40, but not lipopolysaccharide and anti-IgM stimulation of primary B lymphocytes, leads to a persistent nuclear accumulation of RelB.

1996 • 47 citations

Broadened Clinical Utility of Gene Gun-Mediated, Granulocyte-Macrophage Colony-Stimulating Factor cDNA-Based Tumor Cell Vaccines as Demonstrated with a Mouse Myeloma Model

1998 • 44 citations

Adenovector-induced expression of human-CD40-ligand (hCD40L) by multiple myeloma cells

2001 • 40 citations

CD40 Ligand-Induced Apoptosis is Fas-Independent in Human Multiple Myeloma Cells

2000 • 39 citations

Induced Expression of B7-1 on Myeloma Cells Following Retroviral Gene Transfer Results in Tumor-Specific Recognition by Cytotoxic T Cells

1999 • 33 citations

Interleukin-2-Mediated Modulation of Plasma Cell Tumor Growth in a Model of Multiple Myeloma

1998 • 13 citations