Idiotype Vaccination Using Dendritic Cells After Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma—A Feasibility Study

A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

1975 • 3,051 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

A PROSPECTIVE, RANDOMIZED TRIAL OF AUTOLOGOUS BONE MARROW TRANSPLANTATION AND CHEMOTHERAPY IN MULTIPLE MYELOMA

2013 • 2,176 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response

1997 • 1,536 citations

Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability

1996 • 1,138 citations

CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells.

1996 • 1,105 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

Induction of Immune Responses in Patients with B-Cell Lymphoma against the Surface-Immunoglobulin Idiotype Expressed by Their Tumors

1992 • 551 citations

Tumor-Specific Idiotype Vaccines in the Treatment of Patients With B-Cell Lymphoma — Long-Term Results of a Clinical Trial

1997 • 464 citations

Peripheral blood stem cell transplants for multiple myeloma: identification of favorable variables for rapid engraftment in 225 patients

1995 • 459 citations

Immune Reconstitution and Immunotherapy After Autologous Hematopoietic Stem Cell Transplantation

1998 • 334 citations

Myeloma Proteins as Tumor-Specific Transplantation Antigens

1972 • 325 citations

An adjuvant formulation that selectively elicits the formation of antibodies of protective isotypes and of cell-mediated immunity

1986 • 318 citations

Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo

1994 • 300 citations

Generation of Mature Dendritic Cells from Human Blood

1997 • 297 citations

Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor

1995 • 269 citations

DNA immunization induces protective immunity against B–cell lymphoma

1996 • 252 citations

Autoimmune-Like Antibodies to the Ligand-Binding Sites of Myeloma Proteins

1971 • 213 citations

Use of family specific leader region primers for PCR amplification of the human heavy chain variable region gene repertoire

1992 • 190 citations

Idiotype Immunization Combined With Granulocyte-Macrophage Colony-Stimulating Factor in Myeloma Patients Induced Type I, Major Histocompatibility Complex–Restricted, CD8- and CD4-Specific T-Cell Responses

1998 • 189 citations

Peripheral T cell tolerance as a tumor escape mechanism: deletion of CD4⁺ T cells specific for a monoclonal immunoglobulin idiotype secreted by a plasmacytoma

1996 • 165 citations

Idiotype Immunization Combined With Granulocyte-Macrophage Colony-Stimulating Factor in Myeloma Patients Induced Type I, Major Histocompatibility Complex–Restricted, CD8- and CD4-Specific T-Cell Responses

1998 • 161 citations

Naive idiotype-specific CD4+ T cells and immunosurveillance of B-cell tumors.

1994 • 145 citations

Generation of antigen-specific CD8+ CTLs from naive precursors.

1994 • 143 citations

pH gradient elution of human IgG1, IgG2 and IgG4 from protein A-Sepharose

1979 • 137 citations

Idiotypic protein-pulsed adherent peripheral blood mononuclear cell-derived dendritic cells prime immune system in multiple myeloma.

1998 • 133 citations

Preferential use of the VH4 Ig gene family by diffuse large-cell lymphoma

1995 • 129 citations

Idiotype vaccination against murine B cell lymphoma. Humoral and cellular responses elicited by tumor-derived immunoglobulin M and its molecular subunits.

1987 • 118 citations

Idiotype-reactive T-cell subsets and tumor load in monoclonal gammopathies

1995 • 117 citations

Selective Induction of Delayed Hypersensitivity by a Lipid Conjugated Protein Antigen Which Is Localized in Thymus Dependent Lymphoid Tissue

1973 • 101 citations

Modulation of anti‐idiotypic immune response by immunization with the autologous M‐component protein in multiple myeloma patients

1996 • 97 citations

Naive CD4⁺ T cells confer idiotype‐specific tumor resistance in the absence of antibodies

1995 • 86 citations

Recognition of an immunoglobulin VH epitope by influenza virus-specific class I major histocompatibility complex-restricted cytolytic T lymphocytes.

1994 • 61 citations

Idiotype Vaccines for Non-Hodgkin's Lymphoma Induce Polyclonal Immune Responses That Cover Mutated Tumor Idiotypes: Comparison of Different Vaccine Formulations

1997 • 61 citations

Generation of Virtually Pure and Potentially Proliferating Dendritic Cells From Non-CD34 Apheresis Cells From Patients With Multiple Myeloma

1997 • 45 citations

Cellular and molecular basis of human gamma delta T cell activation. Role of accessory molecules in alloactivation.

1995 • 38 citations

Cytotoxic T lymphocyte clone recognizing self idiotype: its regulatory role in antibody production

1987 • 30 citations

Rationale for adjuvant idiotypic vaccination after high-dose therapy for multiple myeloma.

1997 • 29 citations

Immune regulation of mouse 5T2 multiple myeloma. I. Immune response to 5T2 MM idiotype.

1991 • 14 citations

Immune regulation of 5T2 mouse multiple myeloma. II. Immunological treatment of 5T2 MM residual disease.

1991 • 12 citations