CD40 Ligand Induces an Antileukemia Immune Response In Vivo

The Fas Death Factor

1995 • 4,070 citations

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Production of high-titer helper-free retroviruses by transient transfection.

1993 • 2,280 citations

Lymphocyte responses and cytokines

1994 • 1,860 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Molecular and biological characterization of a murine ligand for CD40

1992 • 1,029 citations

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

1990 • 926 citations

IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement.

1980 • 835 citations

Establishment and Characterization of BALB/c Lymphoma Lines with B Cell Properties

1979 • 677 citations

Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity.

1990 • 628 citations

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal.

1993 • 622 citations

CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.

1993 • 593 citations

Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients

1993 • 434 citations

Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region

1987 • 426 citations

CD40 Ligand-Dependent T Cell Activation: Requirement of B7-CD28 Signaling Through CD40

1996 • 421 citations

The distinct surface of human blood dendritic cells, as observed after an improved isolation method.

1990 • 402 citations

Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity

1994 • 334 citations

Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component.

1994 • 308 citations

Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity

1994 • 294 citations

CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway.

1995 • 285 citations

Experimental and Clinical Studies of Cytokine Gene-Modified Tumor Cells

1994 • 259 citations

CD40 preferentially costimulates activation of CD4+ T lymphocytes.

1994 • 255 citations

Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity.

1995 • 224 citations

Combination gene therapy for liver metastasis of colon carcinoma in vivo.

1995 • 222 citations

Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody.

1995 • 197 citations

Role of the CD40‐CD40 ligand interaction in CD4⁺ T cell contact‐dependent activation of monocyte interleukin‐1 synthesis

1994 • 174 citations

Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen

1996 • 173 citations

Resistance to Fas-mediated apoptosis in human hepatoma cells.

1995 • 152 citations

Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen

1996 • 149 citations

Interleukin‐12 and B7.1 co‐stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors

1996 • 130 citations

Fas/APO-1 gene transfer for human malignant glioma.

1995 • 127 citations

CD40 ligand is a T cell growth factor

1993 • 123 citations

Role of B7-1 in mediating an immune response to myeloid leukemia cells

1995 • 122 citations

Transformed cell lines susceptible or resistant to in vivo surveillance against tumorigenesis

1978 • 122 citations

Priming of tumor-specific T cells in the draining lymph nodes after immunization with interleukin 2-secreting tumor cells: three consecutive stages may be required for successful tumor vaccination.

1995 • 94 citations

Human Tumor Antigens Are Ready to Fly

1996 • 85 citations

CD4+ T-cell induction of Fas-mediated apoptosis in Burkitt's lymphoma B cells

1996 • 82 citations

Recombinant CD40 ligand exerts potent biologic effects on T cells.

1994 • 77 citations

A phase-I clinical study of autologous tumor cells plus interleukin-2-gene-transfected allogeneic fibroblasts as a vaccine in patients with cancer

1997 • 69 citations

Successful Culture and Selection of Cytokine Gene-Modified Human Dermal Fibroblasts for the Biologic Therapy of Patients with Cancer

1996 • 46 citations

Functional expression of adhesion receptors and costimulatory molecules by fresh and immortalized B-cell non-Hodgkin's lymphoma cells

1995 • 31 citations

Phase I Study of Cytokine-Gene Modified Autologous Neuroblastoma Cells for Treatment of Relapse/Refractory Neuroblastoma

1992 • 31 citations

Follicular lymphomas can be induced to present alloantigen efficiently: A conceptual model to improve their tumor immunogenicity

1995 • 8 citations

[11] Cell-free expression of large collections of cDNA clones using positive-selection λ phage vectors

1993 • 6 citations