Regulation of Hepatocyte Activator Inhibitor-1 Expression by Androgen and Oncogenic Transformation in the Prostate

In silico prediction of protein-protein interactions in human macrophages

2014 • 11,120 citations

Significance analysis of microarrays applied to the ionizing radiation response

2001 • 10,393 citations

Met, metastasis, motility and more

2003 • 2,526 citations

Delineation of prognostic biomarkers in prostate cancer

2001 • 1,694 citations

Scatter factor/hepatocyte growth factor is essential for liver development

1995 • 1,398 citations

TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia

2004 • 1,346 citations

Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase

1998 • 595 citations

Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.

1992 • 571 citations

The program of androgen-responsive genes in neoplastic prostate epithelium

2002 • 473 citations

Activation of Hepatocyte Growth Factor and Urokinase/Plasminogen Activator by Matriptase, an Epithelial Membrane Serine Protease

2000 • 394 citations

Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA.

1993 • 379 citations

Molecular cloning and sequence analysis of the cDNA for a human serine protease reponsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII

1993 • 373 citations

Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis

2002 • 321 citations

Heat Shock Protein 27 Increases after Androgen Ablation and Plays a Cytoprotective Role in Hormone-Refractory Prostate Cancer

2004 • 305 citations

Hepsin promotes prostate cancer progression and metastasis

2004 • 284 citations

Hepatocyte Growth Factor Activator Inhibitor, a Novel Kunitz-type Serine Protease Inhibitor

1997 • 271 citations

Reverse biochemistry: Use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue

1999 • 254 citations

Purification and Characterization of a Complex Containing Matriptase and a Kunitz-type Serine Protease Inhibitor from Human Milk

1999 • 243 citations

Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer.

2003 • 231 citations

Prostate Stem Cell Compartments

1998 • 224 citations

Molecular Cloning of cDNA for Matriptase, a Matrix-degrading Serine Protease with Trypsin-like Activity

1999 • 223 citations

Intermediate Cells in Human Prostate Epithelium Are Enriched in Proliferative Inflammatory Atrophy

2003 • 205 citations

The Hepatocyte Growth Factor Regulatory Factors in Human Breast Cancer

2004 • 199 citations

Matriptase and HAI-1 Are Expressed by Normal and Malignant Epithelial Cells in Vitro and in Vivo

2001 • 188 citations

Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: correlation with clinical outcome and tumor clinicopathological parameters.

2002 • 186 citations

Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers

2005 • 183 citations

Hepsin activates pro‐hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor‐1B (HAI‐1B) and HAI‐2

2005 • 159 citations

Plasminogen activator inhibitor-1 and tumour growth, invasion, and metastasis

2004 • 155 citations

Hepsin, a cell surface serine protease identified in hepatoma cells, is overexpressed in ovarian cancer.

1997 • 149 citations

Histology and Cellular Kinetics of Prostatic Atrophy

1998 • 142 citations

Regulation of the activity of matriptase on epithelial cell surfaces by a blood‐derived factor

2001 • 139 citations

Activation of hepatocyte growth factor/scatter factor in colorectal carcinoma.

2000 • 128 citations

Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Specific Cell Surface Binding Protein of Hepatocyte Growth Factor Activator (HGFA) and Regulates HGFA Activity in the Pericellular Microenvironment

2000 • 126 citations

Quantitative Proteomic Analysis of Proteins Released by Neoplastic Prostate Epithelium

2004 • 126 citations

Met–HGF/SF: Tumorigenesis, Invasion and Metastasis

2007 • 125 citations

Roles of hepatocyte growth factor (HGF) activator and HGF activator inhibitor in the pericellular activation of HGF/scatter factor.

2003 • 118 citations

Distribution of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1) in Human Tissues: Cellular Surface Localization of HAI-1 in Simple Columnar Epithelium and Its Modulated Expression in Injured and Regenerative Tissues

1999 • 115 citations

Expression of hepatocyte growth factor/scatter factor, its activator, inhibitors and the c-Met receptor in human cancer cells.

2001 • 99 citations

Inadequate formalin fixation decreases reliability of p27Kip1 immunohistochemical staining: Probing optimal fixation time using high-density tissue microarrays

2002 • 95 citations

Normal and Malignant Prostate Epithelial Cells Differ in Their Response to Hepatocyte Growth Factor/Scatter Factor

2001 • 93 citations

Characterization of Prostate Cell Types by CD Cell Surface Molecules

2002 • 87 citations

Prostate Cancer and the Met Hepatocyte Growth Factor Receptor

2004 • 83 citations

Conformational Lability in Serine Protease Active Sites: Structures of Hepatocyte Growth Factor Activator (HGFA) Alone and with the Inhibitory Domain from HGFA Inhibitor-1B

2005 • 71 citations

Growth factors as mediators of androgen action during male urogenital development

1996 • 71 citations

Intermediate cells in normal and malignant prostate epithelium express c‐MET: Implications for prostate cancer invasion

2002 • 65 citations

Expression of hepatocyte growth factor/scatter factor, its activator, inhibitors and the c-Met receptor in human cancer cells

2001 • 60 citations

Multiple Sites of Proteolytic Cleavage to Release Soluble Forms of Hepatocyte Growth Factor Activator Inhibitor Type 1 from a Transmembrane Form

1999 • 47 citations

Syndecan-1 expression in locally invasive and metastatic prostate cancer

2004 • 46 citations

Upregulation of HGF activator inhibitor type 1 but not type 2 along with regeneration of intestinal mucosa

2000 • 41 citations

Pericellular activation of hepatocyte growth factor/scatter factor (HGF/SF) in colorectal carcinomas: roles of HGF activator (HGFA) and HGFA inhibitor type 1 (HAI-1).

2001 • 17 citations