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Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA.

Data up to Jan 2025

Published1993
Citations379
References30

Total Citations Per Year

Abstract

References (30)

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1991 • 2,230 citations

Molecular cloning and expression of human hepatocyte growth factor

1989 • 2,191 citations

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

1987 • 1,333 citations

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

1991 • 1,176 citations

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1984 • 1,153 citations

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1990 • 695 citations

Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor

1989 • 664 citations

Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor

1991 • 509 citations

A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor.

1991 • 502 citations

Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues.

1990 • 333 citations

Control of hepatocyte replication by two serum factors.

1984 • 301 citations

Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding.

1992 • 297 citations

Hepatocyte growth factor is a potent mitogen for cultured rabbit renal tubular epithelial cells

1991 • 259 citations

Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain.

1992 • 253 citations

Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 transformed RPTE

1991 • 253 citations

Partial characterization of a hepatocyte growth factor from rat platelets

1984 • 251 citations

Hepatocyte growth factor increases urokinase-type plasminogen activator (u-PA) and u-PA receptor expression in Madin-Darby canine kidney epithelial cells.

1992 • 219 citations

Hepatocyte growth factor is a potent stimulator of human melanocyte DNA synthesis and growth

1991 • 215 citations

Activation of hepatocyte growth factor by proteolytic conversion of a single chain form to a heterodimer.

1992 • 211 citations

Isolation and expression of cDNA for different forms of hepatocyte growth factor from human leukocyte

1990 • 180 citations

Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer

1992 • 168 citations

The role of urokinase-type plasminogen activator in aggressive tumor cell behavior

1990 • 158 citations

Identification and change in the receptor for hepatocyte growth factor in rat liver after partial hepatectomy or induced hepatitis

1991 • 123 citations

Transplantation system for determining the clonogenic survival of parenchymal hepatocytes exposed to ionizing radiation.

1981 • 102 citations

Processing of hepatocyte growth factor to the heterodimeric form is required for biological activity

1992 • 85 citations

Comparative electrophoretic analysis of human and porcine plasminogen activators in sds-polyacrylamide gels containing plasminogen and casein

1983 • 69 citations

Biological Control of Tissue Plasminogen Activator-Mediated Fibrinolysis

1988 • 44 citations

Characterization of the effects of human placental HGF on rat hepatocytes

1992 • 40 citations

Substrate specificity of tissue-type and urokinase-type plasminogen activators

1991 • 24 citations

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Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA. (1993) – PubMed | Metascience Observatory Explorer