RelB/p50 Dimers Are Differentially Regulated by Tumor Necrosis Factor-α and Lymphotoxin-β Receptor Activation

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

1997 • 4,661 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

The TNF and TNF Receptor Superfamilies

2001 • 3,533 citations

NF-κB at the crossroads of life and death

2002 • 2,684 citations

NF-κB in cancer: from innocent bystander to major culprit

2002 • 2,457 citations

Structure, Regulation and Function of NF-kappaB

1994 • 2,110 citations

Signal transduction by tumor necrosis factor and its relatives

2001 • 1,623 citations

Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

2001 • 1,333 citations

Control of apoptosis by Rel/NF-κB transcription factors

1999 • 1,204 citations

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

1998 • 1,070 citations

Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene

1999 • 978 citations

IKK-γ is an essential regulatory subunit of the IκB kinase complex

1998 • 950 citations

The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis

1999 • 922 citations

NF-κB signaling pathways in mammalian and insect innate immunity

2001 • 892 citations

The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways

2002 • 891 citations

Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase

1999 • 827 citations

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family

1995 • 810 citations

Tumor Necrosis Factor, Other Cytokines and Disease

1993 • 788 citations

The Lymphotoxin β Receptor Controls Organogenesis and Affinity Maturation in Peripheral Lymphoid Tissues

1998 • 710 citations

BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells

2002 • 674 citations

The Crystal Structure of the IκBα/NF-κB Complex Reveals Mechanisms of NF-κB Inactivation

1998 • 563 citations

The NF-κB Activation Pathway: A Paradigm in Information Transfer from Membrane to Nucleus

1999 • 485 citations

IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development

2001 • 469 citations

BAFF/BLyS Receptor 3 Binds the B Cell Survival Factor BAFF Ligand through a Discrete Surface Loop and Promotes Processing of NF-κB2

2002 • 468 citations

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

1999 • 459 citations

RelB Is Essential for the Development of Myeloid-Related CD8α− Dendritic Cells but Not of Lymphoid-Related CD8α+ Dendritic Cells

1998 • 443 citations

NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti

2000 • 435 citations

CD40 regulates the processing of NF-kappaB2 p100 to p52

2002 • 435 citations

Prevention of Constitutive TNF Receptor 1 Signaling by Silencer of Death Domains

1999 • 408 citations

Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice

2001 • 407 citations

RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.

1992 • 375 citations

IKKα controls formation of the epidermis independently of NF-κB

2001 • 357 citations

NF- κ B and the innate immune response

2000 • 332 citations

IκB proteins: structure, function and regulation

1997 • 330 citations

A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site.

1992 • 281 citations

Essential Role of RelB in Germinal Center and Marginal Zone Formation and Proper Expression of Homing Chemokines

2001 • 221 citations

RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF

2002 • 213 citations

RelB Cellular Regulation and Transcriptional Activity Are Regulated by p100

2002 • 213 citations

Transcription of the RelB gene is regulated by NF-κB

2001 • 200 citations

RelB regulation of chemokine expression modulates local inflammation.

1997 • 163 citations

Multifocal defects in immune responses in RelB-deficient mice.

1997 • 131 citations

Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells.

1995 • 126 citations

Constitutive and inducible Rel/NF-kappa B activities in mouse thymus and spleen.

1994 • 120 citations

EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments

1995 • 116 citations

Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity.

1994 • 114 citations

Both N- and C-Terminal Domains of RelB Are Required for Full Transactivation: Role of the N-Terminal Leucine Zipper-Like Motif

1993 • 87 citations

Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent.

1996 • 83 citations

Specific inhibition of RelB/p52 transcriptional activity by the C-terminal domain of p100.

1995 • 80 citations

NF-κB activation by tumor necrosis factor α in the jurkat T cell line is independent of protein kinase A, protein kinase C, and Ca2+-regulated kinases

1991 • 72 citations

Lymphotoxin‐β receptor mediates NEMO‐independent NF‐κB activation

2002 • 71 citations

RelB Modulation of IκBα Stability as a Mechanism of Transcription Suppression of Interleukin-1α (IL-1α), IL-1β, and Tumor Necrosis Factor Alpha in Fibroblasts

1999 • 69 citations

Abnormal organogenesis of Peyer's patches in mice deficient for NF-κB1, NF-κB2, and Bcl-3

2002 • 66 citations

Human T-cell leukemia virus type I Tax-protein-mediated activation of NF-kappa B from p100 (NF-kappa B2)-inhibited cytoplasmic reservoirs.

1994 • 55 citations

Human RelB (I-Rel) functions as a kappa B site-dependent transactivating member of the family of Rel-related proteins.

1994 • 38 citations

Regulation of major histocompatibility complex class I expression by NF-κB-related proteins in breast cancer cells

1998 • 33 citations

Role of TNF ligand and receptor family in the lymphoid organogenesis defined by gene targeting.

1999 • 31 citations

Inducible Activation of RelB in Fibroblasts

1996 • 22 citations

Expression profiling in knockout mice: lymphotoxin versus tumor necrosis factor in the maintenance of splenic microarchitecture

2001 • 12 citations