Expression profiling in knockout mice: lymphotoxin versus tumor necrosis factor in the maintenance of splenic microarchitecture

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

1992 • 5,105 citations

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Serial Analysis of Gene Expression

1995 • 3,659 citations

Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.

1996 • 3,063 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

1999 • 2,326 citations

Genomics, gene expression and DNA arrays

2000 • 2,039 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Cloning the Differences Between Two Complex Genomes

1993 • 1,301 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

A chemokine-driven positive feedback loop organizes lymphoid follicles

2000 • 1,220 citations

Kidney Injury Molecule-1 (KIM-1), a Putative Epithelial Cell Adhesion Molecule Containing a Novel Immunoglobulin Domain, Is Up-regulated in Renal Cells after Injury

1998 • 1,189 citations

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

1996 • 1,167 citations

A Putative Chemokine Receptor, BLR1, Directs B Cell Migration to Defined Lymphoid Organs and Specific Anatomic Compartments of the Spleen

1996 • 1,125 citations

Active Oxygen Species and the Functions of Phagocytic Leukocytes

1980 • 1,124 citations

Gene-expression profile of the ageing brain in mice

2000 • 1,057 citations

Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 • 1,039 citations

Molecular Characterization of Dendritic Cell-Derived Exosomes

1999 • 1,005 citations

Identifying differences in mRNA expression by representational difference analysis of cDNA

1994 • 904 citations

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

1984 • 638 citations

DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES

1999 • 636 citations

Distinct Roles in Lymphoid Organogenesis for Lymphotoxins α and β Revealed in Lymphotoxin β–Deficient Mice

1997 • 590 citations

REGULATION AND INHIBITION OF PHOSPHOLIPASE A₂

1999 • 574 citations

Lymphotoxin α/β and Tumor Necrosis Factor Are Required for Stromal Cell Expression of Homing Chemokines in B and T Cell Areas of the Spleen

1999 • 552 citations

Regulatory Functions of Phospholipase A2

1997 • 551 citations

Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages

1995 • 501 citations

Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface

1993 • 468 citations

BLC Expression in Pancreatic Islets Causes B Cell Recruitment and Lymphotoxin-Dependent Lymphoid Neogenesis

2000 • 450 citations

Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness.

1995 • 436 citations

Recent Advances in Chemokines and Chemokine Receptors

1999 • 414 citations

Chronic inflammation caused by lymphotoxin is lymphoid neogenesis.

1996 • 405 citations

Receptors for a growing family of secreted phospholipases A2

1999 • 396 citations

Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice

1997 • 365 citations

The SRCR superfamily: a family reminiscent of the Ig superfamily

1994 • 359 citations

Lactoferrin: A Multifunctional Glycoprotein Involved in the Modulation of the Inflammatory Process

1999 • 341 citations

cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences.

1990 • 304 citations

Severe Impairment in Early Host Defense againstCandida albicansin Mice Deficient in Myeloperoxidase

1999 • 304 citations

Lymph Node Genesis Is Induced by Signaling through the Lymphotoxin β Receptor

1998 • 294 citations

Regulation and Functional Involvement of Macrophage Scavenger Receptor MARCO in Clearance of Bacteria In Vivo

1999 • 272 citations

Lymphocyte Cytotoxicity in vitro: Activation and Release of a Cytotoxic Factor

1968 • 266 citations

Equalizing cDNA Subtraction Based on Selective Suppression of Polymerase Chain Reaction: Cloning of Jurkat Cell Transcripts Induced by Phytohemaglutinin and Phorbol 12-Myristate 13-Acetate

1996 • 259 citations

Tumor necrosis factor: a master-regulator of leukocyte movement

2000 • 242 citations

Abrogation of the alternative complement pathway by targeted deletion of murine factor B

1997 • 211 citations

Lymphoid Tissue Homing Chemokines Are Expressed in Chronic Inflammation

2000 • 193 citations

Orchestrated Information Transfer Underlying Leukocyte Endothelial Interactions

1996 • 190 citations

Library subtraction ofin vitrocDNA libraries to identify differentially expressed genes in scrapie infection

1990 • 189 citations

A Novel Mutant Gene Involved in T-Lymphocyte–Specific Homing Into Peripheral Lymphoid Organs on Mouse Chromosome 4

1998 • 187 citations

The macrophage receptor MARCO

2000 • 186 citations

BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth.

1994 • 180 citations

Cytotoxic Effect of Lymphocyte-Antigen Interaction in Delayed Hypersensitivity

1967 • 177 citations

Genomic Views of the Immune System

2000 • 174 citations

Lymphoid neoorganogenesis

1999 • 174 citations

DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer.

2000 • 170 citations

Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line.

1985 • 167 citations

Increased susceptibility of TNF-alpha lymphotoxin-alpha double knockout mice to systemic candidiasis through impaired recruitment of neutrophils and phagocytosis of Candida albicans.

1999 • 148 citations

CD6—ligand interactions: a paradigm for SRCR domain function?

1997 • 147 citations

Cloning and Characterization of Novel Mouse and Human Secretory Phospholipase A2s

1999 • 141 citations

Resistance to Endotoxic Shock in Phospholipase A2 Receptor-deficient Mice

1997 • 134 citations

TOGA: An automated parsing technology for analyzing expression of nearly all genes

2000 • 133 citations

The Role of Chemokines in Regulating Cell Migration during Humoral Immune Responses

1999 • 133 citations

Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein

1997 • 131 citations

Indoor coal combustion emissions, GSTM1 and GSTT1 genotypes, and lung cancer risk: a case-control study in Xuan Wei, China

2002 • 127 citations

Subtractive cDNA cloning using oligo(dt)₃₀-latex and PCR: isolation of cDNA clones specific to undifferentiated human embryonal carcinoma cells

1991 • 123 citations

Cloning and Functional Studies of a Novel Gene Aberrantly Expressed in RB-Deficient Embryos

1999 • 120 citations

Cloning and Recombinant Expression of a Novel Mouse-secreted Phospholipase A2

1999 • 113 citations

Glutathione S-transferases M1, T1, and P1 and breast cancer.

2000 • 112 citations

Increased Susceptibility of TNF-α Lymphotoxin-α Double Knockout Mice to Systemic Candidiasis Through Impaired Recruitment of Neutrophils and Phagocytosis ofCandida albicans

1999 • 110 citations

Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1a1, and CYP2e1

2000 • 110 citations

Fungicidal effect of human lactoferrin against Candida albicans

1992 • 97 citations

Macrophage scavenger receptor MARCO: In vitro and in vivo regulation and involvement in the anti-bacterial host defense

1997 • 96 citations

CRP-ductin: A gene expressed in intestinal crypts and in pancreatic and hepatic ducts

1996 • 95 citations

Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBP

1998 • 93 citations

The Membrane-proximal Scavenger Receptor Cysteine-rich Domain of CD6 Contains the Activated Leukocyte Cell Adhesion Molecule Binding Site

1995 • 93 citations

Lung cancer risk in nonsmokers and GSTM1 and GSTT1 genetic polymorphism.

2000 • 92 citations

Interplay between dietary inducers of GST and theGSTM-1 genotype in colon cancer

2000 • 88 citations

From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models

1999 • 86 citations

Chemokines and B-cell Homing to Follicles

1999 • 78 citations

TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes.

1999 • 77 citations

Fungicidal effect of human lactoferrin againstCandida albicans

1992 • 74 citations

Defective co-stimulation and impaired Th1 development in tumor necrosis factor/lymphotoxin-alpha double-deficient mice infected with Candida albicans

1998 • 72 citations

Serial analysis of gene expression: from gene discovery to target identification

2000 • 69 citations

Vezf1:A Zn Finger Transcription Factor Restricted to Endothelial Cells and Their Precursors

1999 • 68 citations

TNF and Lymphotoxin β Cooperate in the Maintenance of Secondary Lymphoid Tissue Microarchitecture But Not in the Development of Lymph Nodes

1999 • 65 citations

Roles of a Macrophage Receptor with Collagenous Structure(MARCO) in Host Defense and Heterogeneity of Splenic Marginal Zone Macrophages.

1999 • 64 citations

BST-1/CD157 Regulates the Humoral Immune Responses in vivo

2000 • 63 citations

Deletion of Bone Marrow Stromal Cell Antigen-1 (CD157) Gene Impaired Systemic Thymus Independent-2 Antigen-Induced IgG3 and Mucosal TD Antigen-Elicited IgA Responses

1998 • 63 citations

The Bb fragment of complement factor B acts as a B cell growth factor.

1988 • 62 citations

Identification of differentialy expressed genes by restirction endonuclease-based gene expression fingerprinting

1995 • 61 citations

Differential gene expression in CD3e- and RAG1-deficient thymuses: definition of a set of genes potentially involved in thymocyte maturation

1999 • 59 citations

cDNA expression arrays reveal incomplete reversal of age-related changes in gene expression by calorie restriction

2000 • 57 citations

A novel surface molecule of bone marrow stromal cells that supports pre-B cell growth.

1994 • 57 citations

Augmentation of Human Macrophage Candidacidal Capacity by Recombinant Human Myeloperoxidase and GranulocyteMacrophage Colony-Stimulating Factor

1998 • 51 citations

Molecular Cloning of a Novel Human cDNA Encoding a Zinc Finger Protein That Binds to the Interleukin-3 Promoter

1994 • 49 citations

The murine BP-3 gene encodes a relative of the CD38/NAD glycohydrolase family

1994 • 47 citations

Identification of differentially expressed genes in nasopharyngeal carcinoma by means of the Atlas human cancer cDNA expression array

2000 • 46 citations

Rapid analysis of gene expression (RAGE) facilitates universal expression profiling

1999 • 45 citations

Lymphocyte homing: The scent of a follicle

1997 • 43 citations

Reticular cells in peripheral lymphoid tissues express the phosphatidylinositol‐linked BP‐3 antigen

1991 • 40 citations

Molecular cloning of a novel human cDNA encoding a zinc finger protein that binds to the interleukin-3 promoter.

1994 • 31 citations

Growth-supporting activity of fragment Ba of the human alternative complement pathway for activated murine B lymphocytes.

1986 • 29 citations

BP-3 alloantigen. A cell surface glycoprotein that marks early B lineage cells and mature myeloid lineage cells in mice.

1988 • 29 citations

Defence of mucous membranes by antibodies, receptor analogues and non-specific host factors

1985 • 25 citations

Structure and Chromosomal Localization of the Human and Murine Genes for the Macrophage MARCO Receptor

1999 • 24 citations

SPLASH (PLA2IID), a novel member of phospholipase A2 family, is associated with lymphotoxin deficiency

2000 • 24 citations

Mice Deficient for the Complement Factor B Develop and Reproduce Normally

1998 • 20 citations

Gene profiling approach in the analysis of lymphotoxin and TNF deficiencies

2000 • 20 citations

Developmental expression of a mucinlike glycoprotein (MUCLIN) in pancreas and small intestine of CF mice

1998 • 16 citations