Transcription of the RelB gene is regulated by NF-κB

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1995 • 1,849 citations

Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB

1999 • 1,001 citations

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family

1995 • 810 citations

Expression of relB is required for the development of thymic medulla and dendritic cells

1995 • 794 citations

Apoptosis inhibitory activity of cytoplasmic p21Cip1/WAF1 in monocytic differentiation

1999 • 587 citations

p21WAF1/Cip1: more than a break to the cell cycle?

2000 • 482 citations

RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.

1992 • 375 citations

Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family.

1993 • 331 citations

Sequential Induction of NF-κB/Rel Family Proteins during B-Cell Terminal Differentiation

1994 • 275 citations

The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation.

1992 • 258 citations

Distinct NF-κB/Rel transcription factors are responsible for tissue-specific and inducible gene activation

1993 • 225 citations

I-Rel: a novel rel-related protein that inhibits NF-kappa B transcriptional activity.

1992 • 167 citations

Expression of relB transcripts during lymphoid organ development: specific expression in dendritic antigen-presenting cells

1993 • 149 citations

Nuclear localization of RelB is associated with effective antigen-presenting cell function.

1997 • 137 citations

Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity.

1994 • 114 citations

Transcriptional Regulation of NF-κB2: Evidence for κB-Mediated Positive and Negative Autoregulation

1994 • 112 citations

RelB, a New Rel Family Transcription Activator That Can Interact with p50-NF-κB

1992 • 110 citations

Two distinct mechanisms contribute to the constitutive activation of RelB in lymphoid cells.

1994 • 91 citations

Both N- and C-Terminal Domains of RelB Are Required for Full Transactivation: Role of the N-Terminal Leucine Zipper-Like Motif

1993 • 87 citations

Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent.

1996 • 83 citations

Differential Expression of the Transcription Factor NF-κB during Human Mononuclear Phagocyte Differentiation to Macrophages and Dendritic Cells

2000 • 80 citations

IκB Kinase-Dependent Chronic Activation of NF-κB Is Necessary for p21^WAF1/Cip1 Inhibition of Differentiation-Induced Apoptosis of Monocytes

2001 • 69 citations

Induction of p21Waf1/Cip1 by TNFα requires NF-κB activity and antagonizes apoptosis in Ewing tumor cells

2000 • 68 citations

Regulation of I kappa B alpha and p105 in monocytes and macrophages persistently infected with human immunodeficiency virus

1995 • 59 citations

Pleiotropic effects of Bcl-2 on transcription factors in T cells: potential role of NF-_KB p50–p50 for the anti-apoptotic function of Bcl-2

1995 • 48 citations

CD40, but not lipopolysaccharide and anti-IgM stimulation of primary B lymphocytes, leads to a persistent nuclear accumulation of RelB.

1996 • 47 citations

Transcriptional elongation of c-myb is regulated by NF-κB (p50/RelB)

1999 • 41 citations

cAMP-induced NF-κB (p50/relB) binding to a c-myb intronic enhancer correlates with c-myb up-regulation and inhibition of erythroleukemia cell differentiation

1997 • 41 citations

Receptor-specific induction of NF-kappaB components in primary B cells

1998 • 38 citations

Both N- and C-terminal domains of RelB are required for full transactivation: role of the N-terminal leucine zipper-like motif.

1993 • 36 citations

Iκκ Mediates NF-κB Activation in Human Immunodeficiency Virus-Infected Cells

1999 • 33 citations

Induction of Nuclear Factor-κB During Primary B Cell Differentiation

1998 • 31 citations

Discrimination between RelA and RelB Transcriptional Regulation by a Dominant Negative Mutant of IκBα

1998 • 25 citations

Inducible Activation of RelB in Fibroblasts

1996 • 22 citations

The Structure of the Nuclear Factor-κB Protein-DNA Complex Varies with DNA-binding Site Sequence

2000 • 21 citations

Prevention of Tumor Necrosis Factor (TNF)-Mediated Induction of p21WAF1/CIP1Sensitizes MCF-7 Carcinoma Cells to TNF-Induced Apoptosis

1998 • 16 citations

Differential expression of Rel/NF-κB and octamer factors is a hallmark of the generation and maturation of dendritic cells

2000 • 15 citations