Molecular pathways regulating mobilization of marrow-derived stem cells for tissue revascularization

Isolation of Putative Progenitor Endothelial Cells for Angiogenesis

1997 • 8,673 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Mechanisms of angiogenesis

1997 • 5,696 citations

Bone marrow cells regenerate infarcted myocardium

2001 • 5,234 citations

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Bone Marrow Origin of Endothelial Progenitor Cells Responsible for Postnatal Vasculogenesis in Physiological and Pathological Neovascularization

1999 • 3,280 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem Cell

2001 • 2,653 citations

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1995 • 2,650 citations

Neovascularization of ischemic myocardium by human bone-marrow–derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function

2001 • 2,583 citations

Angiogenesis.

1992 • 2,581 citations

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

1999 • 2,425 citations

Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors

2000 • 2,286 citations

Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF

1999 • 2,176 citations

Mobilized bone marrow cells repair the infarcted heart, improving function and survival

2001 • 2,133 citations

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

2001 • 1,874 citations

Transplantation ofex vivoexpanded endothelial progenitor cells for therapeutic neovascularization

2000 • 1,869 citations

VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

1999 • 1,852 citations

Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand

2002 • 1,755 citations

Dependence of Human Stem Cell Engraftment and Repopulation of NOD/SCID Mice on CXCR4

1999 • 1,714 citations

Evidence for Circulating Bone Marrow-Derived Endothelial Cells

1998 • 1,666 citations

Origins of circulating endothelial cells and endothelial outgrowth from blood

2000 • 1,529 citations

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1992 • 1,528 citations

Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration

1995 • 1,525 citations

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

1996 • 1,355 citations

Hematopoietic Stem Cell Quiescence Maintained by p21 ^cip1/waf1

2000 • 1,326 citations

MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis

2000 • 1,306 citations

Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

1999 • 1,248 citations

Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis

2002 • 1,170 citations

Origin of endothelial progenitors in human postnatal bone marrow

2002 • 1,121 citations

In vitro differentiation of endothelial cells from AC133-positive progenitor cells

2000 • 1,001 citations

Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice

1999 • 990 citations

Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon

1999 • 916 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Origin of endothelial progenitors in human postnatal bone marrow

2002 • 880 citations

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

1996 • 855 citations

Vascular Trauma Induces Rapid but Transient Mobilization of VEGFR2 ⁺ AC133 ⁺ Endothelial Precursor Cells

2001 • 802 citations

Vascular Endothelial Growth Factor and Angiopoietin-1 Stimulate Postnatal Hematopoiesis by Recruitment of Vasculogenic and Hematopoietic Stem Cells

2001 • 692 citations

Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization

2002 • 682 citations

Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment

2002 • 638 citations

Endothelial Progenitor Cell Vascular Endothelial Growth Factor Gene Transfer for Vascular Regeneration

2002 • 587 citations

The chemokine SDF-1 stimulates integrin-mediated arrest of CD34+ cells on vascular endothelium under shear flow

1999 • 569 citations

Plasma elevation of stromal cell–derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells

2001 • 530 citations

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.

1991 • 516 citations

Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

1997 • 512 citations

KDR Receptor: A Key Marker Defining Hematopoietic Stem Cells

1999 • 491 citations

Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice

2000 • 490 citations

Transplanted Adult Bone Marrow Cells Repair Myocardial Infarcts in Mice

2001 • 435 citations

Vascular Endothelial Growth Factor Upregulates the Expression of Matrix Metalloproteinases in Vascular Smooth Muscle Cells

1998 • 428 citations

Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization

2000 • 426 citations

The Genetic Program of Hematopoietic Stem Cells

2000 • 422 citations

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression.

1996 • 351 citations

Bone marrow–derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis

2002 • 333 citations

Subsecond Induction of α4 Integrin Clustering by Immobilized Chemokines Stimulates Leukocyte Tethering and Rolling on Endothelial Vascular Cell Adhesion Molecule 1 under Flow Conditions

2000 • 327 citations

Enhanced endothelialization and microvessel formation in polyester grafts seeded with CD34+ bone marrow cells

2000 • 277 citations

Vascular Endothelial Growth Factor (VEGF) and VEGF Receptor 2(flk-1) Are Expressed during Vasculogenesis and Vascular Differentiation in the Quail Embryo

1995 • 270 citations

Manipulating Angiogenesis

1997 • 260 citations

Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice.

2001 • 199 citations

Angioblast differentiation and morphogenesis of the vascular endothelium in the mouse embryo

1991 • 181 citations

Evidence that embryonic kidney cells expressing flk-1 are intrinsic, vasculogenic angioblasts

1996 • 177 citations

Blood-borne seeding by hematopoietic and endothelial precursors from the allantois

1998 • 162 citations

Stromal-derived factor 1–induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases

2000 • 161 citations

Characterization of hematopoietic cells arising on the textured surface of left ventricular assist devices

1995 • 122 citations

Endothelial cells genetically selected from differentiating mouse embryonic stem cells incorporate at sites of neovascularization in vivo

2002 • 121 citations

Tat–Human Immunodeficiency Virus-1 Induces Human Monocyte Chemotaxis by Activation of Vascular Endothelial Growth Factor Receptor-1

1997 • 108 citations

Relationship between selectin-mediated rolling of hematopoietic stem and progenitor cells and progression in hematopoietic development

2000 • 90 citations

Predominant expression of a receptor tyrosine kinase, TIE, in hematopoietic stem cells and B cells

1996 • 68 citations

Human Cord Blood Progenitors Sustain Thymic T-Cell Development and a Novel Form of Angiogenesis

1999 • 64 citations

Putting the neo into neoangiogenesis

2002 • 59 citations

Predominant expression of a receptor tyrosine kinase, TIE, in hematopoietic stem cells and B cells

1996 • 56 citations

Systemic activation of the vascular endothelial growth factor receptor KDR/flk-1 selectively triggers endothelial cells with an angiogenic phenotype.

1997 • 42 citations