A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

Oncogenes and signal transduction

1991 • 2,816 citations

Patterns of Amino Acids near Signal‐Sequence Cleavage Sites

1983 • 2,290 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.

1990 • 982 citations

Compilation of published signal sequences

1984 • 784 citations

Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus

1982 • 611 citations

A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells

1990 • 611 citations

Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes

1989 • 610 citations

A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

1991 • 606 citations

Steel locus defines new multipotent growth factor

1990 • 509 citations

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

1989 • 495 citations

Development and applications of a molecular genetic linkage map of the mouse genome

1991 • 427 citations

Genetics and Probability in Animal Breeding Experiments

1981 • 425 citations

Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction.

1989 • 413 citations

A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1.

1989 • 399 citations

Developmental expression of c-kit, a proto-oncogene encoded by the W locus

1990 • 349 citations

Cellular and developmental properties of fetal hematopoietic stem cells

1990 • 317 citations

Growth and Differentiation in the Hemopoietic System

1987 • 220 citations

Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation.

1991 • 209 citations

Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors.

1985 • 173 citations

Receptor tyrosine kinases: genetic evidence for their role in Drosophila and mouse development

1990 • 161 citations