The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1995 • 2,650 citations

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo

1992 • 2,293 citations

The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

1992 • 2,042 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

1994 • 1,661 citations

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1994 • 1,249 citations

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.

1994 • 1,104 citations

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

1992 • 1,103 citations

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor.

1991 • 999 citations

Interleukin‐8, a chemotactic and inflammatory cytokine

1992 • 941 citations

Tissue factor and hemostasis [published erratum appears in Blood 1988 Apr;71(4):1178]

1988 • 941 citations

Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing.

1992 • 880 citations

Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration.

1990 • 857 citations

Human Endothelial Cells: Use of Heparin in Cloning and Long-Term Serial Cultivation

1983 • 801 citations

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.

1993 • 764 citations

Tissue factor and hemostasis [published erratum appears in Blood 1988 Apr;71(4):1178]

1988 • 670 citations

Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis.

1988 • 655 citations

Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs.

1994 • 616 citations

In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease

1996 • 544 citations

Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice.

1994 • 488 citations

A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF.

1995 • 480 citations

Characterization of Novel Vascular Endothelial Growth Factor (VEGF) Receptors on Tumor Cells That Bind VEGF165 via Its Exon 7-encoded Domain

1996 • 345 citations

Coordinate expression of vascular endothelial growth factor receptor‐1 (fit‐1) and its ligand suggests a paracrine regulation of murine vascular development

1995 • 288 citations

Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary.

1992 • 259 citations

A Heparin-Binding Form of Placenta Growth Factor (PlGF-2) is Expressed in Human Umbilical Vein Endothelial Cells and in Placenta

1993 • 245 citations

Endothelial monocyte-activating polypeptide II. A novel tumor-derived polypeptide that activates host-response mechanisms.

1992 • 173 citations

Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes

1993 • 167 citations

Hypoxia and platelet‐derived growth factor‐BB synergistically upregulate the expression of vascular endothelial growth factor in vascular smooth muscle cells

1995 • 165 citations

Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes

1993 • 127 citations

Characterization of the receptor to vasculotropin on bovine adrenal cortex-derived capillary endothelial cells.

1990 • 120 citations

Specific binding of vascular permeability factor to endothelial cells

1991 • 86 citations

Specificity of Vascular Endothelial Cell Growth Factor Receptor Ligand Binding Domains

1994 • 83 citations

Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells

1993 • 66 citations