MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis

The Hallmarks of Cancer

2000 • 27,569 citations

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

2000 • 2,700 citations

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.

2000 • 1,945 citations

Stem Cells

2000 • 1,783 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis

2000 • 1,604 citations

Changing views of the role of matrix metalloproteinases in metastasis

1997 • 1,585 citations

Matrix Metalloproteinases: Biologic Activity and Clinical Implications

2000 • 1,533 citations

Carcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium

2000 • 1,445 citations

ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

1997 • 1,311 citations

Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1985 • 1,292 citations

Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

1999 • 937 citations

The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis

1999 • 916 citations

Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention

1999 • 840 citations

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

1997 • 612 citations

Matrix metal loproteinases and the development of cancer

1996 • 569 citations

Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.

1986 • 531 citations

Molecular pathology of cyclooxygenase-2 in neoplasia.

2000 • 406 citations

Extracellular matrix signaling: integration of form and function in normal and malignant cells

1998 • 360 citations

The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis

1999 • 359 citations

Matrix Metalloproteinases (MMPs) and Their Physiological Inhibitors (TIMPs) Are Differentially Expressed during Excisional Skin Wound Repair

1998 • 331 citations

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice

1994 • 295 citations

In Vivo Evidence That the Stromelysin-3 Metalloproteinase Contributes in a Paracrine Manner to Epithelial Cell Malignancy

1998 • 290 citations

High expression of 92-kD type IV collagenase (gelatinase B) in the osteoclast lineage during mouse development

1994 • 286 citations

Metalloproteinases mediate extracellular matrix degradation by cells from mouse blastocyst outgrowths

1992 • 221 citations

Secretion of metalloproteinases by stimulated capillary endothelial cells. I. Production of procollagenase and prostromelysin exceeds expression of proteolytic activity.

1986 • 215 citations

Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice.

1996 • 202 citations

Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture

1991 • 181 citations

Gelatinase B: Structure, Regulation, and Function

1998 • 176 citations

Use of keratin antibodies in tumor diagnosis.

1990 • 160 citations

Extrinsic regulators of epithelial tumor progression: metalloproteinases

2000 • 149 citations

Cross-species comparison of angiogenesis during the premalignant stages of squamous carcinogenesis in the human cervix and K14-HPV16 transgenic mice.

1997 • 126 citations

Matrix metalloproteinases and metastatic cancer.

1998 • 121 citations

Heterogeneous Stem Cells in Skin Homeostatis and Wound Repair

2015 • 77 citations

Human T lymphocytes synthesize the 92 kDa type IV collagenase (gelatinase B)

1993 • 69 citations

Expression of extracellular matrix-degrading metalloproteinases and metalloproteinase inhibitors is developmentally regulated during endoderm differentiation of embryonal carcinoma cells

1990 • 41 citations

Synthesis of viruslike particles by expression of the putative capsid protein of Leishmania RNA virus in a recombinant baculovirus expression system

1994 • 39 citations

Matrix Metalloproteinases

1998 • 8 citations