Evolutionary relationships among Rel domains indicate functional diversification by recombination

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

NF-κB: Ten Years After

1996 • 3,008 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1991 • 1,054 citations

Identification of a Putative Regulator of Early T Cell Activation Genes

1988 • 933 citations

Nuclear Export of NF-ATc Enhanced by Glycogen Synthase Kinase-3

1997 • 754 citations

Generic Signals and Specific Outcomes

1999 • 732 citations

DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

1991 • 604 citations

NF-AT components define a family of transcription factors targeted in T-cell activation

1994 • 573 citations

Tonicity-responsive enhancer binding protein, a Rel-like protein that stimulates transcription in response to hypertonicity

1999 • 568 citations

Structure of NF-κB p50 homodimer bound to a κB site

1995 • 564 citations

Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression

1996 • 535 citations

Structure of the NF-κB p50 homodimer bound to DNA

1995 • 525 citations

L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

1999 • 521 citations

Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA

1998 • 510 citations

Dorsal , an Embryonic Polarity Gene in Drosophila , Is Homologous to the Vertebrate Proto-Oncogene, c- rel

1987 • 485 citations

A radiation hybrid map of the human genome

1996 • 457 citations

A Protein Encoded within the Down Syndrome Critical Region Is Enriched in Striated Muscles and Inhibits Calcineurin Signaling

2000 • 414 citations

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction.

1997 • 403 citations

Sequential Phosphorylation by Mitogen-activated Protein Kinase and Glycogen Synthase Kinase 3 Represses Transcriptional Activation by Heat Shock Factor-1

1996 • 381 citations

NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun

1999 • 373 citations

Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression inSaccharomyces cerevisiae

1997 • 328 citations

An STS-Based Radiation Hybrid Map of the Human Genome

1997 • 323 citations

Cotranslational Biogenesis of NF-κB p50 by the 26S Proteasome

1998 • 312 citations

A conserved family of calcineurin regulators

2000 • 300 citations

A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart

1995 • 264 citations

Yeast calcineurin regulates nuclear localization of the Crz1p transcription factor through dephosphorylation

1999 • 242 citations

Origin of Genes

1997 • 236 citations

NFATx, a Novel Member of the Nuclear Factor of Activated T Cells Family That Is Expressed Predominantly in the Thymus

1995 • 211 citations

The tonicity-sensitive element that mediates increased transcription of the betaine transporter gene in response to hypertonic stress.

1994 • 202 citations

Interaction of calcineurin with a domain of the transcription factor NFAT1 that controls nuclear import.

1996 • 173 citations

Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, inCryptococcus neoformans

2000 • 171 citations

NFATc3, a Lymphoid-specific NFATc Family Member That Is Calcium-regulated and Exhibits Distinct DNA Binding Specificity

1995 • 168 citations

Transcription of the Sodium/myo-Inositol Cotransporter Gene Is Regulated by Multiple Tonicity-responsive Enhancers Spread over 50 Kilobase Pairs in the 5′-Flanking Region

1998 • 168 citations

Glycogen Synthase Kinase 3β Negatively Regulates Both DNA-binding and Transcriptional Activities of Heat Shock Factor 1

2000 • 154 citations

EID: the Exon-Intron Database--an exhaustive database of protein-coding intron-containing genes

2000 • 139 citations

A Viral Mechanism for Inhibition of the Cellular Phosphatase Calcineurin

1998 • 136 citations

Evolution of the intron-exon structure of eukaryotic genes

1995 • 127 citations

Characterization of reticuloendotheliosis virus strain T DNA and isolation of a novel variant of reticuloendotheliosis virus strain T by molecular cloning

1981 • 118 citations

Rapid targeting of nuclear proteins to the cytoplasm

1997 • 112 citations

Solution Structure of the Core NFATC1/DNA Complex

1998 • 107 citations

Integration of the Cytogenetic, Genetic, and Physical Maps of the Human Genome by FISH Mapping of CEPH YAC Clones

1996 • 105 citations

Identification of a Physical Interaction between Calcineurin and Nuclear Factor of Activated T Cells (NFATp)

1996 • 104 citations

Identification of a putative regulator of early T cell activation genes. Science. 1988. 241: 202-205.

2010 • 98 citations

Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc

1997 • 96 citations

Evolution and structure of the fibrinogen genes

1985 • 85 citations

Intron Distribution in Ancient Paralogs Supports Random Insertion and Not Random Loss

1997 • 74 citations

A symmetric-iterated multiple alignment of protein sequences

1998 • 67 citations