IκB: a Specific Inhibitor of the NF-κB Transcription Factor

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

1987 • 999 citations

Nuclear localization of unoccupied oestrogen receptors

1984 • 882 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

Transcriptional selectivity of viral genes in mammalian cells

1986 • 722 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor

1988 • 607 citations

Simian virus 40 DNA replication in vitro.

1984 • 562 citations

The Role of Protein Kinase C in Transmembrane Signalling

1986 • 557 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation

1988 • 535 citations

A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters

1985 • 446 citations

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1987 • 428 citations

The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV

1988 • 427 citations

GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.

1987 • 395 citations

Specific interaction between enhancer-containing molecules and cellular components

1984 • 374 citations

Antibodies to two major chicken heat shock proteins cross-react with similar proteins in widely divergent species.

1982 • 316 citations

Inducible binding of a factor to the c-fos enhancer

1986 • 310 citations

Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter.

1988 • 308 citations

Compilation of transcription regulating proteins

1988 • 303 citations

A short nucleotide sequence required for regulation of HIS4 by the general control system of yeast

1983 • 288 citations

Oligonucleotide that binds nuclear factor NF-kappa B acts as a lymphoid-specific and inducible enhancer element.

1988 • 275 citations

Immunoglobulin Heavy-Chain Enhancer Requires One or More Tissue-Specific Factors

1985 • 271 citations

Relationship of the 90-kDa murine heat shock protein to the untransformed and transformed states of the L cell glucocorticoid receptor.

1987 • 267 citations

A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex.

1988 • 267 citations

The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous

1987 • 260 citations

Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro.

1987 • 238 citations

Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes.

1986 • 201 citations

Requirement of hormone for thermal conversion of the glucocorticoid receptor to a DNA-binding state

1988 • 186 citations

Distinct factors bind to apparently homolgous sequences in the immunoglobulin heavy-chain enhancer

1986 • 161 citations

Simian virus 40 early- and late-region promoter functions are enhanced by the 72-base-pair repeat inserted at distant locations and inverted orientations.

1983 • 149 citations

Cell type-specific transcriptional enhancement in vitro requires the presence of trans-acting factors.

1985 • 127 citations

A labile inhibitor blocks immunoglobulin kappa-light-chain-gene transcription in a pre-B leukemic cell line.

1986 • 109 citations

Phorbol-ester-induced Activation of the NF- B Transcription Factor Involves Dissociation of an Apparently Cytoplasmic NF- B/Inhibitor Complex

1988 • 94 citations

Nuclear factor NF-kappa B can interact functionally with its cognate binding site to provide lymphoid-specific promoter function.

1988 • 77 citations

Chapter 9 Mass Enucleation of Cultured Animal Cells

1974 • 36 citations