Mechanism of rhodopsin phosphorylation

Techniques in Protein Chemistry

1993 • 1,285 citations

Constitutively active mutants of rhodopsin

1992 • 513 citations

Structure and mechanism of the G protein-coupled receptor kinases.

1993 • 480 citations

β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family

1989 • 451 citations

Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites

1982 • 441 citations

Light dependent phosphorylation of rhodopsin by ATP

1972 • 370 citations

Phosphorylation of Frog Photoreceptor Membranes induced by Light

1972 • 332 citations

Molecular mechanism of visual transduction

1989 • 312 citations

Mechanism of rhodopsin kinase activation

1991 • 301 citations

Signal flow in visual transduction

1992 • 238 citations

Role of acidic amino acids in peptide substrates of the .beta.-adrenergic receptor kinase and rhodopsin kinase

1991 • 220 citations

G-protein-coupled receptor kinases

1991 • 219 citations

The role of arrestin and retinoids in the regeneration pathway of rhodopsin.

1992 • 217 citations

Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family

1991 • 214 citations

Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase

1986 • 205 citations

Sequential phosphorylation of rhodopsin at multiple sites

1993 • 204 citations

Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase.

1992 • 196 citations

Phosphorylation of rhodopsin and quenching of cyclic GMP phosphodiesterase activation by ATP at weak bleaches.

1983 • 165 citations

The influence of arrestin (48K protein) and rhodopsin kinase on visual transduction

1992 • 151 citations

Purification and characterization of rhodopsin kinase.

1988 • 149 citations

Mechanism of ATP quench of phosphodiesterase activation in rod disc membranes.

1983 • 144 citations

Light-stimulated Phosphorylation of Bovine Visual Pigments by Adenosine Triphosphate

1973 • 143 citations

Mass spectrometric identification of phosphorylation sites in bleached bovine rhodopsin

1993 • 140 citations

Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin.

1993 • 139 citations

Molecular cloning and expression of GRK6. A new member of the G protein-coupled receptor kinase family.

1993 • 139 citations

Phosphorylation sites in bovine rhodopsin

1993 • 129 citations

Light-dependent phosphorylation of rhodopsin in living frogs

1974 • 128 citations

Rhodopsin kinase: substrate specificity and factors that influence activity

1988 • 125 citations

Interaction between photoactivated rhodopsin and its kinase: Stability and kinetics of complex formation

1993 • 122 citations

Light activation of one rhodopsin molecule causes the phosphorylation of hundreds of others. A reaction observed in electropermeabilized frog rod outer segments exposed to dim illumination.

1990 • 110 citations

Rhodopsin Kinase Activity in the Mammalian Pineal Gland and Other Tissues

1984 • 109 citations

Mechanistic studies on the phosphorylation of photoexcited rhodopsin

1988 • 105 citations

A novel G protein-coupled receptor kinase gene cloned from 4p16.3

1992 • 99 citations

A splice variant of arrestin. Molecular cloning and localization in bovine retina.

1994 • 96 citations

Phosphorylation of ovine rhodopsin. Identification of the phosphorylated sites

1984 • 95 citations

Control of Rhodopsin Multiple Phosphorylation

1994 • 95 citations

Characterization of a truncated form of arrestin isolated from bovine rod outer segments

1994 • 92 citations

The catalytic subunit of phosphatase 2A dephosphorylates phosphoopsin

1989 • 86 citations

Effect of bleached rhodopsin on signal amplification in rod visual receptors

1990 • 80 citations

Substrate recognition determinants for rhodopsin kinase: studies with synthetic peptides, polyanions, and polycations

1989 • 80 citations

In vivo farnesylation of rat rhodopsin kinase

1992 • 77 citations

Transducin activation in electropermeabilized frog rod outer segments is highly amplified, and a portion equivalent to phosphodiesterase remains membrane-bound.

1990 • 75 citations

Identification of the autophosphorylation sites in rhodopsin kinase.

1992 • 72 citations

Characterization of rhodopsin kinase purified from bovine rod outer segments.

1990 • 71 citations

Opsins with mutations at the site of chromophore attachment constitutively activate transducin but are not phosphorylated by rhodopsin kinase.

1994 • 48 citations

Dim background light and Cerenkov radiation from³²P block reversal of rhodopsin phosphorylation in intact frog retinal rods

1991 • 48 citations

Nucleoside inhibitors of rhodopsin kinase

1990 • 44 citations

Phosphorylation of iodopsin, chicken red-sensitive cone visual pigment

1990 • 42 citations

Molecular, enzymatic and functional properties of rhodopsin kinase from rat pineal gland

1990 • 27 citations