Interaction between photoactivated rhodopsin and its kinase: Stability and kinetics of complex formation

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments.

1986 • 781 citations

Amplification and kinetics of the activation steps in phototransduction

1993 • 645 citations

THE MOLAR EXTINCTION OF RHODOPSIN

1953 • 444 citations

Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites

1982 • 441 citations

Rhodopsin phosphorylation as a mechanism of cyclic GMP phosphodiesterase regulation by S-modulin

1993 • 401 citations

Rhodopsin Mutants That Bind But Fail to Activate Transducin

1990 • 377 citations

Three cytoplasmic loops of rhodopsin interact with transducin.

1989 • 370 citations

[8] Preparation of retinal rod outer segments

1982 • 279 citations

Light-dependent delay in the falling phase of the retinal rod photoresponse

1992 • 232 citations

The role of arrestin and retinoids in the regeneration pathway of rhodopsin.

1992 • 217 citations

Primary and secondary structure of bovine retinal S antigen (48-kDa protein).

1987 • 200 citations

Kinetics, binding constant, and activation energy of the 48-kDa protein-rhodopsin complex by extra-metarhodopsin II

1989 • 193 citations

Inactivation of photoexcited rhodopsin in retinal rods: the roles of rhodopsin kinase and 48-kDa protein (arrestin)

1988 • 185 citations

The influence of arrestin (48K protein) and rhodopsin kinase on visual transduction

1992 • 151 citations

Two different forms of metarhodopsin II: Schiff base deprotonation precedes proton uptake and signaling state.

1993 • 148 citations

Amplification of phosphodiesterase activation is greatly reduced by rhodopsin phosphorylation

1986 • 130 citations

The transitory complex between photoexcited rhodopsin and transducin

1989 • 129 citations

Interaction of rhodopsin with the G‐protein, transducin

1993 • 125 citations

Rhodopsin kinase: substrate specificity and factors that influence activity

1988 • 125 citations

Phosphorylated rhodopsin and heparin induce similar conformational changes in arrestin.

1991 • 121 citations

Regulation of rhodopsin kinase by autophosphorylation.

1991 • 120 citations

Light activation of one rhodopsin molecule causes the phosphorylation of hundreds of others. A reaction observed in electropermeabilized frog rod outer segments exposed to dim illumination.

1990 • 110 citations

Chapter 10 Interactions of Rod Cell Proteins with the Disk Membrane: Influence of Light, Ionic Strength, and Nucleotides

1981 • 106 citations

Reaction rate and collisional efficiency of the rhodopsin-transducin system in intact retinal rods

1991 • 103 citations

Deactivation kinetics of the transduction cascade of vision.

1991 • 101 citations

G-protein-effector coupling: A real-time light-scattering assay for transducin-phosphodiesterase interaction

1993 • 99 citations

Identification of the autophosphorylation sites in rhodopsin kinase.

1992 • 72 citations

Binding of inositol phosphates to arrestin

1991 • 67 citations

Interaction between photoexcited rhodopsin and peripheral enzymes in frog retinal rods

1983 • 65 citations

Photic modulation of a highly sensitive, near-infrared light-scattering signal recorded from intact retinal photoreceptors.

1988 • 62 citations

Kinetic study on the equilibrium between membrane-bound and free photoreceptor G-protein

1987 • 50 citations

Interplay between hydroxylamine, metarhodopsin II and GTP-binding protein in bovine photoreceptor membranes

1983 • 50 citations

Mechanism of activation of sensory rhodopsin I: evidence for a steric trigger.

1991 • 45 citations

Displacement of rhodopsin by GDP from three-loop interaction with transducin depends critically on the diphosphate beta-position.

1990 • 41 citations

Activation of rhodopsin phosphorylation is triggered by the lumirhodopsin–metarhodopsin I transition

1983 • 41 citations

Kinetic analysis of the activation of transducin by photoexcited rhodopsin. Influence of the lateral diffusion of transducin and competition of guanosine diphosphate and guanosine triphosphate for the nucleotide site

1992 • 35 citations

Mutations Probe Structure and Function of G-protein Chains

1988 • 34 citations

Structural properties of arrestin studied by chemical modification and circular dichroism

1992 • 26 citations