G-protein-coupled receptor kinases

Turning off the signal: desensitization of β‐adrenergic receptor function

1990 • 1,241 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

β-Arrestin: a Protein that Regulates β-adrenergic Receptor Function

1990 • 1,162 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family

1989 • 451 citations

The carboxy-terminal segment of the yeast α-factor receptor is a regulatory domain

1988 • 317 citations

Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein.

1985 • 312 citations

Mechanism of rhodopsin kinase activation

1991 • 301 citations

Purification and characterization of the beta-adrenergic receptor kinase.

1987 • 241 citations

Role of acidic amino acids in peptide substrates of the .beta.-adrenergic receptor kinase and rhodopsin kinase

1991 • 220 citations

Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family

1991 • 214 citations

The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis.

1987 • 199 citations

Chapter 5 Interactions between photoexcited rhodopsin and light-activated enzymes in rods

1984 • 174 citations

Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase.

1987 • 156 citations

Purification and characterization of rhodopsin kinase.

1988 • 149 citations

Regulation of Rhodopsin Dephosphorylation by Arrestin

1989 • 134 citations

Phosphorylation of chick heart muscarinic cholinergic receptors by the .beta.-adrenergic receptor kinase

1989 • 133 citations

Rhodopsin kinase: substrate specificity and factors that influence activity

1988 • 125 citations

Rhodopsin Kinase Activity in the Mammalian Pineal Gland and Other Tissues

1984 • 109 citations

Mechanistic studies on the phosphorylation of photoexcited rhodopsin

1988 • 105 citations

Somatostatin induces translocation of the beta-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells.

1987 • 103 citations

Ligand-induced phosphorylation of the cAMP receptor from Dictyostelium discoideum.

1988 • 99 citations

Phosphorylation of ovine rhodopsin. Identification of the phosphorylated sites

1984 • 95 citations

The catalytic subunit of phosphatase 2A dephosphorylates phosphoopsin

1989 • 86 citations

Substrate recognition determinants for rhodopsin kinase: studies with synthetic peptides, polyanions, and polycations

1989 • 80 citations

Characterization of rhodopsin kinase purified from bovine rod outer segments.

1990 • 71 citations

Interplay of phosphorylation and dephosphorylation in vision: protein phosphatases of bovine rod outer segments

1989 • 61 citations

Synthetic peptides of the hamster beta 2‐adrenoceptor as substrates and inhibitors of the beta‐adrenoceptor kinase.

1990 • 60 citations

Nucleoside inhibitors of rhodopsin kinase

1990 • 44 citations

Phosphorylation of iodopsin, chicken red-sensitive cone visual pigment

1990 • 42 citations

<b>AGONIST-DEPENDENT PHOSPHORYLATION OF CEREBRAL AND ATRIAL MUSCARINIC RECEPTORS: BLOCKADE OF THE PHOSPHORYLATION BY GTP-BINDING REGULATORY PROTEINS AND ITS REVERSAL BY GUANINE </b><b>NUCLEOTIDES </b>

1989 • 31 citations

Molecular, enzymatic and functional properties of rhodopsin kinase from rat pineal gland

1990 • 27 citations

Light-induced phosphorylation of proteins from the all-cone retina of the lizard, Anolis carolinensis.

1986 • 26 citations