The macrophage haunted by cell ghosts: a pathogen grows

The expanding universe of T-cell subsets: Th1, Th2 and more

1996 • 3,710 citations

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

1998 • 3,085 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

Natural adjuvants: Endogenous activators of dendritic cells

1999 • 1,611 citations

A receptor for phosphatidylserine-specific clearance of apoptotic cells

2000 • 1,480 citations

Consequences of Cell Death

2000 • 1,382 citations

Immature Dendritic Cells Phagocytose Apoptotic Cells via αvβ5 and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes

1998 • 1,226 citations

Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity.

1997 • 1,109 citations

MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment

1999 • 973 citations

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha.

1996 • 920 citations

Complement-dependent Clearance of Apoptotic Cells by Human Macrophages

1998 • 692 citations

Efficient Presentation of Phagocytosed Cellular Fragments on the Major Histocompatibility Complex Class II Products of Dendritic Cells

1998 • 649 citations

Unequal Death in T Helper Cell (Th)1 and Th2 Effectors: Th1, but not Th2, Effectors Undergo Rapid Fas/FasL-mediated Apoptosis

1997 • 460 citations

Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages

2000 • 452 citations

The microbicidal activity of interferon‐γ‐treated macrophages against Trypanosoma cruzi involves an L‐arginine‐dependent, nitrogen oxide‐mediated mechanism inhibitable by interleukin‐10 and transforming growth factor‐β

1992 • 437 citations

Bystander apoptosis triggers dendritic cell maturation and antigen-presenting function.

1998 • 353 citations

Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease

1999 • 350 citations

Apoptosis: The importance of being eaten

1998 • 349 citations

Immunogenicity of Apoptotic Cells In Vivo: Role of Antigen Load, Antigen-Presenting Cells, and Cytokines

1999 • 295 citations

Cutting Edge: Bystander Apoptosis Triggers Dendritic Cell Maturation and Antigen-Presenting Function

1998 • 295 citations

Processing of engulfed apoptotic bodies yields T cell epitopes.

1997 • 267 citations

The selective engulfment of apoptotic bodies by dendritic cells is mediated by the αvβ3 integrin and requires intracellular and extracellular calcium

1997 • 262 citations

Cross-presentation: a general mechanism for CTL immunity and tolerance

1998 • 253 citations

Salmonella-Induced Apoptosis of Infected Macrophages Results in Presentation of a Bacteria-Encoded Antigen after Uptake by Bystander Dendritic Cells

2000 • 248 citations

Chagas Disease Etiology: Autoimmunity or Parasite Persistence?

1999 • 225 citations

Antiinflammatory Effects of CD95 Ligand (FasL)-induced Apoptosis

1998 • 220 citations

Maintaining the Immunological Balance in Parasitic Infections: A Role for TGF-β?

2000 • 194 citations

CD14-dependent clearance of apoptotic cells: relevance to the immune system

2000 • 191 citations

Transforming growth factor-beta stimulates arginase activity in macrophages. Implications for the regulation of macrophage cytotoxicity.

1995 • 186 citations

Activation-induced CD4+ T cell death by apoptosis in experimental Chagas' disease.

1995 • 184 citations

The Multiplex Function of Nitric Oxide in (Auto)immunity

1998 • 175 citations

Cutting Edge: Differential Effect of Apoptotic Versus Necrotic Tumor Cells on Macrophage Antitumor Activities

1999 • 142 citations

Phagocytosis and development: back to the future

1999 • 125 citations

TGF-β Mediates CTLA-4 Suppression of Cellular Immunity in Murine Kalaazar

2000 • 104 citations

Activation-Induced T Cell Death ExacerbatesTrypanosoma cruziReplication in Macrophages Cocultured with CD4+ T Lymphocytes from Infected Hosts

1998 • 84 citations