The activation domain of the enhancer binding protein p45NF-E2 interacts with TAF II 130 and mediates long-range activation of the α- and β-globin gene loci in an erythroid cell line

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.

1994 • 1,512 citations

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome

1995 • 994 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoeitin/MGDF in megakaryocyte development

1995 • 712 citations

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic–leucine zipper protein

1993 • 655 citations

TBP, a universal eukaryotic transcription factor?

1993 • 642 citations

The "beta-like-globin" gene domain in human erythroid cells.

1985 • 634 citations

Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

1995 • 620 citations

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

1995 • 572 citations

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

1995 • 546 citations

Transcription complex stability and chromatin dynamics in vivo

1995 • 488 citations

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

1987 • 440 citations

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

1994 • 434 citations

A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives

1990 • 386 citations

Cloning of an Intrinsic Human TFIID Subunit That Interacts with Multiple Transcriptional Activators

1995 • 385 citations

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

1994 • 374 citations

The Molecular Basis of Blood Diseases

1994 • 370 citations

Different activation domains stimulate transcription from remote (‘enhancer’) and proximal (‘promoter’) positions.

1992 • 359 citations

Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

1995 • 351 citations

A dominant control region from the human β-globin locus conferring integration site-independent gene expression

1989 • 346 citations

Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells.

1990 • 301 citations

The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene.

1993 • 260 citations

Transcription activation in cells lacking TAFIIs

1996 • 238 citations

A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene

1984 • 237 citations

The 5′HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sites.

1991 • 231 citations

An enhancer stimulates transcription in Trans when attached to the promoter via a protein bridge

1989 • 202 citations

Interaction Between Transcription Regulatory Regions of Prolactin Chromatin

1993 • 197 citations

Transcriptional regulation of multigene loci: multilevel control

1993 • 187 citations

Analysis of Mice Containing a Targeted Deletion of β-Globin Locus Control Region 5′ Hypersensitive Site 3

1996 • 179 citations

Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner.

1993 • 169 citations

Cis-acting sequences regulating expression of the human α-globin cluster lie within constitutively open chromatin

1992 • 162 citations

Dependence of Globin Gene Expression in Mouse Erythroleukemia Cells on the NF-E2 Heterodimer

1995 • 158 citations

Identification of a stage selector element in the human gamma-globin gene promoter that fosters preferential interaction with the 5′ HS2 enhancer when in competition with the beta-promoter.

1992 • 148 citations

Cloning and functional characterization of LCR-F1: a bZIP transcription factor that activates erythroid-specific, human globin gene expression

1994 • 144 citations

NF-E2 and GATA binding motifs are required for the formation of DNase I hypersensitive site 4 of the human beta-globin locus control region.

1995 • 137 citations

Retroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: evidence that NF-E2 is essential for globin expression.

1994 • 135 citations

Molecular cloning and analysis of two subunits of the human TFIID complex: hTAF _II 130 and hTAF _II 100

1996 • 130 citations

p53 oligomerization and DNA looping are linked with transcriptional activation.

1994 • 127 citations

Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein.

1995 • 117 citations

beta-globin dominant control region interacts differently with distal and proximal promoter elements.

1990 • 112 citations

NF-E2 Disrupts Chromatin Structure at Human β-Globin Locus Control Region Hypersensitive Site 2 In Vitro

1996 • 104 citations

The Two-Hybrid System to Detect Protein-Protein Interactions

1993 • 96 citations

In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction.

1992 • 95 citations

Essential Role of NF-E2 in Remodeling of Chromatin Structure and Transcriptional Activation of the ε-Globin Gene In Vivo by 5′ Hypersensitive Site 2 of the β-Globin Locus Control Region

1996 • 93 citations

Beta-globin locus activation regions: conservation of organization, structure, and function.

1990 • 75 citations

RETRACTED: TAFIIs Mediate Activation of Transcription in the Drosophila Embryo

1996 • 64 citations

TAFIIs Mediate Activation of Transcription in theDrosophilaEmbryo

1998 • 61 citations

Identification of Two Novel Regulatory Elements within the 5′-Untranslated Region of the Human Sγ-Globin Gene

1995 • 50 citations

Transcription revisited: a commentary on the 1995 Cold Spring Harbor Laboratory meeting, "Mechanisms of Eukaryotic Transcription".

1996 • 46 citations

Differential phylogenetic footprinting as a means to identify base changes responsible for recruitment of the anthropoid gamma gene to a fetal expression pattern.

1994 • 45 citations

Purification of the Human NF-E2 Complex: cDNA Cloning of the Hematopoietic Cell-Specific Subunit and Evidence for an Associated Partner

1993 • 43 citations

In Vivo Footprinting of the Human α-Globin Locus Upstream Regulatory Element by Guanine and Adenine Ligation-Mediated Polymerase Chain Reaction

1992 • 26 citations

Coactivators and TAFs: A New Class of Eukaryotic Transcription Factors That Connect Activators to the Basal Machinery

1993 • 25 citations

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