In Vivo Footprinting of the Human α-Globin Locus Upstream Regulatory Element by Guanine and Adenine Ligation-Mediated Polymerase Chain Reaction

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new method for sequencing DNA.

1977 • 7,941 citations

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1989 • 972 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

The "beta-like-globin" gene domain in human erythroid cells.

1985 • 634 citations

Activity and tissue-specific expression of the transcription factor NF-E1 multigene family.

1990 • 629 citations

The erythroid-specific transcription factor eryf1: A new finger protein

1989 • 608 citations

K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin

1979 • 532 citations

An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes.

1988 • 518 citations

Globin gene regulation and switching: Circa 1990

1990 • 463 citations

Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice

1990 • 364 citations

Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors

1987 • 356 citations

A major positive regulatory region located far upstream of the human alpha-globin gene locus.

1990 • 337 citations

Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene

1989 • 326 citations

Detailed analysis of the site 3 region of the human beta-globin dominant control region.

1990 • 320 citations

Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells.

1990 • 301 citations

The beta-globin dominant control region: hypersensitive site 2.

1990 • 295 citations

Human gamma- to beta-globin gene switching in transgenic mice.

1990 • 291 citations

Cis- and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deaminase gene.

1989 • 272 citations

Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites.

1989 • 240 citations

The 5′HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sites.

1991 • 231 citations

Chromatin differences between active and inactive X chromosomes revealed by genomic footprinting of permeabilized cells using DNase I and ligation-mediated PCR.

1991 • 195 citations

Characterization of the Major Regulatory Element Upstream of the Human a-Globin Gene Cluster

1991 • 175 citations

The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome.

1990 • 155 citations

Hypersensitive site 4 of the human β globin locus control region

1991 • 141 citations

Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein

1990 • 140 citations

Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster

1990 • 112 citations

beta-globin dominant control region interacts differently with distal and proximal promoter elements.

1990 • 112 citations

Conservation of the primary structure, organization, and function of the human and mouse beta-globin locus-activating regions.

1990 • 112 citations

Synergistic enhancement of globin gene expression by activator protein-1-like proteins.

1990 • 105 citations

Beta-globin locus activation regions: conservation of organization, structure, and function.

1990 • 75 citations

Functional properties of the beta-globin locus control region in K562 erythroleukemia cells

1991 • 66 citations

Activation of phenotypic expression of human globin genes from nonerythroid cells by chromosome-dependent transfer to tetraploid mouse erythroleukemia cells

1979 • 38 citations