Beta-globin locus activation regions: conservation of organization, structure, and function.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

The "beta-like-globin" gene domain in human erythroid cells.

1985 • 634 citations

A developmentally stable chromatin structure in the human beta-globin gene cluster.

1986 • 391 citations

Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice

1990 • 364 citations

A dominant control region from the human β-globin locus conferring integration site-independent gene expression

1989 • 346 citations

Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression.

1990 • 322 citations

Detailed analysis of the site 3 region of the human beta-globin dominant control region.

1990 • 320 citations

The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

1989 • 302 citations

Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells.

1990 • 301 citations

The beta-globin dominant control region: hypersensitive site 2.

1990 • 295 citations

Human gamma- to beta-globin gene switching in transgenic mice.

1990 • 291 citations

Regulated expression of human Aγ-, β-, and hybrid γβ-globin genes in transgenic mice: Manipulation of the developmental expression patterns

1986 • 275 citations

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice.

1989 • 269 citations

Molecular analysis of the human beta-globin locus activation region.

1989 • 218 citations

Developmental regulation of a cloned adult β-globin gene in transgenic mice

1985 • 215 citations

Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.

1989 • 122 citations

The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice.

1989 • 112 citations

High-level erythroid expression of human alpha-globin genes in transgenic mice.

1989 • 96 citations

Nucleotide sequence of the BALB/c mouse β-globin complex

1989 • 89 citations

High-level, erythroid-specific expression of the human alpha-globin gene in transgenic mice and the production of human hemoglobin in murine erythrocytes.

1989 • 83 citations

Complete nucleotide sequence of the rabbit β-like globin gene cluster

1989 • 73 citations

Simultaneous purification of DNA and RNA from small numbers of eukaryotic cells

1989 • 62 citations

Nucleotide sequence of 16-kilobase pairs of DNA 5' to the human epsilon-globin gene.

1985 • 61 citations

Triplication of a four-gene set during evolution of the goat beta-globin locus produced three genes now expressed differentially during development.

1984 • 46 citations

A versatile and simplified non-random strategy for nucleotide sequencing

1987 • 13 citations

Active chromatin

1989 • 12 citations

Application of partial restriction procedure in both shotgun and non-random strategies for nucleotide sequencing

1988 • 4 citations