Regulation of CD8 ⁺ T Cell Development by Thymus-Specific Proteasomes

STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

1996 • 2,408 citations

Structure of 20S proteasome from yeast at 2.4Å resolution

1997 • 2,211 citations

Positive and Negative Selection of T Cells

2003 • 1,547 citations

DEGRADATION OF CELL PROTEINS AND THE GENERATION OF MHC CLASS I-PRESENTED PEPTIDES

1999 • 898 citations

Normal Development of Mice Deficient in β ₂ M, MCClass I Proteins, and CD8 ⁺ T Cells

1990 • 885 citations

Selecting and maintaining a diverse T-cell repertoire

1999 • 712 citations

Central tolerance: learning self-control in the thymus

2005 • 641 citations

Positive selection of lymphocytes

1994 • 563 citations

MHC Class I Expression in Mice Lacking the Proteasome Subunit LMP-7

1994 • 520 citations

The Structure of the Mammalian 20S Proteasome at 2.75 Å Resolution

2002 • 514 citations

Lymphostromal interactions in thymic development and function

2001 • 461 citations

Importance of the Different Proteolytic Sites of the Proteasome and the Efficacy of Inhibitors Varies with the Protein Substrate

2006 • 411 citations

Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly

1996 • 390 citations

26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide

2001 • 322 citations

Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.

1994 • 314 citations

Generation of a complete thymic microenvironment by MTS24+ thymic epithelial cells

2002 • 290 citations

The MHC class I ligand‐generating system: roles of immunoproteasomes and the interferon‐4gMY‐inducible proteasome activator PA28

1998 • 288 citations

Dependence of Self-Tolerance on TRAF6-Directed Development of Thymic Stroma

2005 • 272 citations

Post-proteasomal antigen processing for major histocompatibility complex class I presentation

2004 • 267 citations

Analysis of thymic stromal cell populations using flow cytometry

2002 • 206 citations

Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis.

1996 • 191 citations

Thymic selection revisited: how essential is it?

2003 • 186 citations

Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta

2001 • 155 citations

A cd3⁻ subset of cd4⁻8⁺ thymocytes: a rapidly cycling intermediate in the generation of cd4⁺8⁺ cells

1988 • 152 citations

Structural studies of class I major histocompatibility complex proteins: insights into antigen presentation

1995 • 61 citations