Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A3/J3-Isoprostanes) in Vivo from Eicosapentaenoic Acid

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis

2007 • 2,392 citations

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

1990 • 1,896 citations

Resolvins

2002 • 1,575 citations

Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing

2000 • 1,136 citations

Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells

2003 • 965 citations

Electrospray mass spectrometry of phospholipids

2003 • 884 citations

Polyunsaturated fatty acids, inflammation, and immunity

2001 • 765 citations

Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids.

1992 • 742 citations

Clinical Prevention of Sudden Cardiac Death by n-3 Polyunsaturated Fatty Acids and Mechanism of Prevention of Arrhythmias by n-3 Fish Oils

2003 • 617 citations

Resolvin D1 and Its Aspirin-triggered 17R Epimer

2007 • 503 citations

Formation of Isoprostane-like Compounds (Neuroprostanes) in Vivo from Docosahexaenoic Acid

1998 • 421 citations

Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic Acid-derived Substrates and Products*

2007 • 388 citations

Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro.

1983 • 334 citations

Unified mechanism for polyunsaturated fatty acid autoxidation. Competition of peroxy radical hydrogen atom abstraction, .beta.-scission, and cyclization

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Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes.

1994 • 305 citations

Fatty Acid Substrate Specificities of Human Prostaglandin-endoperoxide H Synthase-1 and −2

1995 • 294 citations

Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis

2004 • 293 citations

Novel n-3 Fatty Acid Oxidation Products Activate Nrf2 by Destabilizing the Association between Keap1 and Cullin3

2006 • 270 citations

[32] Chemistry of lipid peroxidation

1984 • 219 citations

Release of Free F2-isoprostanes from Esterified Phospholipids Is Catalyzed by Intracellular and Plasma Platelet-activating Factor Acetylhydrolases

2005 • 212 citations

Structural Identification of a Novel Pro-inflammatory Epoxyisoprostane Phospholipid in Mildly Oxidized Low Density Lipoprotein

1999 • 208 citations

A nomenclature system for the isoprostanes

1997 • 196 citations

Epoxyisoprostane and Epoxycyclopentenone Phospholipids Regulate Monocyte Chemotactic Protein-1 and Interleukin-8 Synthesis

2002 • 182 citations

Prevention of sudden cardiac death by n−3 polyunsaturated fatty acids

2003 • 178 citations

Oxidized Omega-3 Fatty Acids Inhibit NF-κB Activation Via a PPARα-Dependent Pathway

2004 • 176 citations

Are fish oils beneficial in the prevention and treatment of coronary artery disease?

1997 • 168 citations

Formation of Reactive Cyclopentenone Compounds in Vivo as Products of the Isoprostane Pathway

1999 • 161 citations

Essential fatty acids, lipid peroxidation and apoptosis

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Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPARα

2002 • 157 citations

Identification of fatty acids by electrospray mass spectrometry and tandem mass spectrometry

1996 • 139 citations

Formation of F-ring Isoprostane-like Compounds (F3-Isoprostanes) in Vivo from Eicosapentaenoic Acid

2006 • 129 citations

Formation and antiproliferative effect of prostaglandin E3 from eicosapentaenoic acid in human lung cancer cells

2004 • 118 citations

Identification and Relative Quantitation of F2-Isoprostane Regioisomers Formed in vivo in the Rat

1997 • 116 citations

Formation of Highly Reactive A-ring and J-ring Isoprostane-like Compounds (A4/J4-neuroprostanes) in Vivo from Docosahexaenoic Acid

2002 • 90 citations

Essential fatty acids as determinants of lipid requirements in infants, children and adults

1999 • 88 citations

Formation of Novel D-Ring and E-Ring Isoprostane-like Compounds (D₄/E₄-Neuroprostanes) in Vivo from Docosahexaenoic Acid

2000 • 80 citations

Analysis of novel hydroperoxides and other metabolites of oleic, linoleic, and linolenic acids by liquid chromatography‐mass spectrometry with ion trap MSⁿ

1998 • 79 citations

Unsaturated fatty acids and their oxidation products stimulate CD36 gene expression in human macrophages

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Use of fish oil in parenteral nutrition: rationale and reality

2006 • 72 citations

Identification of Monohydroxy Fatty Acids by Electrospray Mass Spectrometry and Tandem Mass Spectrometry

1996 • 70 citations

Separation and identification of phospholipid peroxidation products

2001 • 63 citations

Eicosapentaenoic and Docosahexaenoic Acids Reduce PGH Synthase 1 Expression in Bovine Aortic Endothelial Cells

1997 • 56 citations

Fast atom bombardment and collision-induced dissociation of prostaglandins and thromboxanes: Some examples of charge remote fragmentation

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Identification of Novel Autoxidation Products of the ω-3 Fatty Acid Eicosapentaenoic Acid in Vitro and in Vivo

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Inhibition of phagocyte-endothelium interactions by oxidized fatty acids: A natural anti-inflammatory mechanism?

1996 • 50 citations

Analysis of oxidized glycerophosphocholine lipids using electrospray ionization mass spectrometry and microderivatization techniques

2000 • 48 citations

In Vivo and in Vitro Lipid Peroxidation of Arachidonate Esters: The Effect of Fish Oil ω-3 Lipids on Product Distribution

2006 • 41 citations

Novel Pathways and Endogenous Mediators in Anti-Inflammation and Resolution

2003 • 36 citations

Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins

2004 • 35 citations

Enhancement of lipid peroxidation and of the antitumor effect of hyperthermia upon combination with oral eicosapentaenoic acid

2002 • 31 citations

Mechanisms of enhanced apoptosis in HL-60 cells by UV-irradiated n-3 and n-6 polyunsaturated fatty acids

2003 • 31 citations

Oxidized ω–3 Fatty Acids Inhibit Pro-Inflammatory Responses in Glomerular Endothelial Cells

2004 • 19 citations

Effects of various fatty acids alone or combined with vitamin E on cell growth and fibrinogen concentration in the medium of HepG2 cells

1995 • 9 citations

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