Unsaturated fatty acids and their oxidation products stimulate CD36 gene expression in human macrophages

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL

1998 • 1,771 citations

Quantitation of mRNA by the polymerase chain reaction.

1989 • 1,648 citations

CD36 is a receptor for oxidized low density lipoprotein

1993 • 1,271 citations

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

1999 • 1,157 citations

Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36.

1993 • 982 citations

A Null Mutation in Murine CD36 Reveals an Important Role in Fatty Acid and Lipoprotein Metabolism

1999 • 758 citations

Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats

1999 • 739 citations

REGULATION OF GENE EXPRESSION BY DIETARY FAT

1999 • 667 citations

Identification of glycoprotein IV (CD36) as a primary receptor for platelet-collagen adhesion

1989 • 490 citations

CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes

1989 • 474 citations

CBP: A Signal-Regulated Transcriptional Coactivator Controlled by Nuclear Calcium and CaM Kinase IV

1998 • 420 citations

Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL

1998 • 361 citations

Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytes

1997 • 325 citations

Coordinate regulation of glycolytic and lipogenic gene expression by polyunsaturated fatty acids.

1994 • 297 citations

Native and Modified Low Density Lipoproteins Increase the Functional Expression of the Macrophage Class B Scavenger Receptor, CD36

1997 • 266 citations

The Peroxisome Proliferator-activated Receptor δ Promotes Lipid Accumulation in Human Macrophages

2001 • 263 citations

Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-γ

2000 • 239 citations

Oleic Acid Inhibits Endothelial Activation

1999 • 217 citations

Long-chain fatty acid-induced changes in gene expression in neonatal cardiac myocytes

2000 • 173 citations

CD36 deficiency associated with insulin resistance

2002 • 169 citations

Transforming Growth Factor-β1 (TGF-β1) and TGF-β2 Decrease Expression of CD36, the Type B Scavenger Receptor, through Mitogen-activated Protein Kinase Phosphorylation of Peroxisome Proliferator-activated Receptor-γ

2000 • 168 citations

Regulation of Monocyte CD36 and Thrombospondin-1 Expression by Soluble Mediators

1996 • 166 citations

Linoleic acid and its metabolites, hydroperoxyoctadecadienoic acids, stimulate c-Fos, c-Jun, and c-Myc mRNA expression, mitogen-activated protein kinase activation, and growth in rat aortic smooth muscle cells.

1995 • 143 citations

Influence of n-6 versus n-3 Polyunsaturated Fatty Acids in Diets Low in Saturated Fatty Acids on Plasma Lipoproteins and Hemostatic Factors

1997 • 128 citations

Structural and metabolic requirements for activators of the peroxisome proliferator-activated receptor

1993 • 121 citations

Regulation of FAT/CD36 gene expression: further evidence in support of a role of the protein in fatty acid binding/transport

1997 • 111 citations

Oxidized LDL Increases and Interferon-γ Decreases Expression of CD36 in Human Monocyte–Derived Macrophages

1998 • 105 citations

A controlled study on the effects of n − 3 fatty acids on lipid and glucose metabolism in non-insulin-dependent diabetic patients

1991 • 98 citations

Inhibition of IL-1β expression in THP-1 cells by probucol and tocopherol

1991 • 94 citations

Effects of medium chain fatty acids (MCFA), myristic acid, and oleic acid on serum lipoproteins in healthy subjects

1997 • 93 citations

Cellular cholesterol regulates expression of the macrophage type B scavenger receptor, CD36

1999 • 92 citations

Unsaturated Fatty Acids Increase Plasminogen Activator Inhibitor-1 Expression in Endothelial Cells

1998 • 90 citations

Vascular Biology of CD36: Roles of this New Adhesion Molecule Family in Different Disease States

1997 • 69 citations

Regulation of macrophage gene expression by peroxisome-proliferator-activated receptor y

1999 • 61 citations

N‐3 but not N‐6 fatty acids reduce the expression of the combined adhesion and scavenger receptor CD36 in human monocytic cells

1995 • 57 citations

Lovastatin Decreases the Receptor-Mediated Degradation of Acetylated and Oxidized LDLs in Human Blood Monocytes During the Early Stage of Differentiation Into Macrophages

1999 • 49 citations

A Single Nucleotide Insertion in Codon 317 of the CD36 Gene Leads to CD36 Deficiency

1996 • 49 citations

Induction of CD36 by all‐trans retinoic acid: retinoic acid receptor signaling in the pathogenesis of atherosclerosis

2001 • 47 citations

Uptake and activation of eicosapentaenoic acid are related to accumulation of triacylglycerol in Ramos cells dying from apoptosis

2000 • 45 citations

Oxidized Lipoproteins Including HDL and Their Lipid Peroxidation Products Inhibit TNF- α Secretion by THP-1 Human Macrophages

1997 • 39 citations

Effects of lipid-lowering diets enriched with monounsaturated and polyunsaturated fatty acids on serum lipoprotein composition in patients with hyperlipoproteinaemia

1992 • 34 citations

Diets enriched in unsaturated fatty acids enhance apolipoprotein A-I catabolism but do not affect either its production or hepatic mRNA abundance in cynomolgus monkeys

1995 • 27 citations

Rapid quantitation of mRNA species in ethidium bromide-stained gels of competitive RT-PCR products.

1994 • 23 citations

Interferon-γ suppresses PDGF production from THP-1 cells and blood monocyte-derived macrophages

1992 • 22 citations

Inhibition of fatty acid synthesis in rat hepatocytes by exogenous polyunsaturated fatty acids is caused by lipid peroxidation

1993 • 22 citations

Arachidonate and medium-chain fatty acids inhibit transcription of the acetyl-CoA carboxylase gene in hepatocytes in culture

1997 • 21 citations

2,4-Decadienal downregulates TNF-α gene expression in THP-1 human macrophages

2001 • 18 citations

Inhibitory effects of arachidonic acid (20:4,n-6) and its monohydroperoxy- and hydroxy-metabolites on procoagulant activity in endothelial cells

1995 • 14 citations

The double bond in unsaturated fatty acids is the necessary and sufficient requirement for the inhibition of expression of endothelial leukocyte adhesion molecules through interference with nuclear factor‐κB activation

1999 • 8 citations