Formation of Isoprostane-like Compounds (Neuroprostanes) in Vivo from Docosahexaenoic Acid

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

1991 • 4,669 citations

Diagnosis of Alzheimer's Disease

1985 • 2,482 citations

Oxidative Stress Hypothesis in Alzheimer's Disease

1997 • 2,355 citations

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

1990 • 1,896 citations

Oxidative Stress in Neurodegenerative Diseases

1996 • 1,336 citations

Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids.

1992 • 742 citations

Health Effects of Polyunsaturated Fatty Acids in Seafoods

1986 • 565 citations

The isoprostanes: Unique bioactive products of lipid peroxidation

1997 • 561 citations

Noncyclooxygenase oxidative formation of a series of novel prostaglandins: Analytical ramifications for measurement of eicosanoids

1990 • 480 citations

Elevated 4-Hydroxynonenal in Ventricular Fluid in Alzheimer’s Disease

1997 • 403 citations

Astrocytes, Not Neurons, Produce Docosahexaenoic Acid (22:6ω‐3) and Arachidonic Acid (20:4ω‐6)

1991 • 322 citations

Alterations in the Fatty Acid Composition of Rat Brain Cells (Neurons, Astrocytes, and Oligodendrocytes) and of Subcellular Fractions (Myelin and Synaptosomes) Induced by a Diet Devoid of n‐3 Fatty Acids

1984 • 321 citations

The generation and actions of isoprostanes

1997 • 314 citations

Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes.

1994 • 305 citations

Essential Fatty Acids: The Importance of n-3 Fatty Acids in the Retina and Brain

2009 • 239 citations

[16] Mass spectrometry of prostanoids: F2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism

1994 • 225 citations

A nomenclature system for the isoprostanes

1997 • 196 citations

The nervous system has an absolute molecular species requirement for proper function

1995 • 141 citations

Reactive oxygen species and the neurodegenerative disorders.

1997 • 141 citations

Differences in the fatty acid composition of the grey and white matter of different regions of the brains of patients with Alzheimer's disease and control subjects

1993 • 136 citations

Effect of oxygen tension on the generation of F2-isoprostanes and malondialdehyde in peroxidizing rat liver microsomes

1994 • 130 citations

Nonenzymatic Free Radical-catalyzed Generation of Thromboxane-like Compounds (Isothromboxanes) in Vivo

1996 • 117 citations

N-Butylboronate derivatives of the F prostaglandins

1971 • 70 citations

Central nervous system lipoproteins in Alzheimer's disease.

1997 • 58 citations

Mass spectra of prostaglandins and related products.

1989 • 20 citations