Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing

Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men

1997 • 5,442 citations

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial

1999 • 3,818 citations

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico.

1999 • 2,021 citations

Anti-inflammatory Properties of Cytochrome P450 Epoxygenase-Derived Eicosanoids

1999 • 1,158 citations

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

1997 • 990 citations

A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1.

1992 • 727 citations

Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions.

1995 • 694 citations

Inflammation: Basic Principles and Clinical Correlates

2000 • 616 citations

Prevention of Sudden Cardiac Death by Dietary Pure ω-3 Polyunsaturated Fatty Acids in Dogs

1999 • 404 citations

Workshop on the Essentiality of and Recommended Dietary Intakes for Omega-6 and Omega-3 Fatty Acids

1999 • 374 citations

Design of Lipoxin A4 Stable Analogs That Block Transmigration and Adhesion of Human Neutrophils

1995 • 326 citations

Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product.

1984 • 304 citations

Prostaglandin H synthases, nonsteroidal antiinflammatory drugs, and colon cancer

1997 • 290 citations

The discovery and function of COX-2.

1997 • 268 citations

Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion

1999 • 219 citations

Aspirin

1991 • 219 citations

Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitmentin vivo

1999 • 209 citations

The Highly Stereoselective Oxidation of Polyunsaturated Fatty Acids by Cytochrome P450BM-3

1996 • 176 citations

The Genesis of Ores

1991 • 157 citations

Epoxidation of unsaturated fatty acids by a soluble cytochrome P-450-dependent system from Bacillus megaterium.

1981 • 133 citations

Analysis of Hydroperoxide-Induced Tyrosyl Radicals and Lipoxygenase Activity in Aspirin-Treated Human Prostaglandin H Synthase-2

1997 • 122 citations

Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA.

1998 • 103 citations

Inhibitory effects of docosahexaenoic acid on colon carcinoma 26 metastasis to the lung

1997 • 94 citations

Transcellular Regulation of Eicosanoid Biosynthesis

2003 • 54 citations

Inhibition of phagocyte-endothelium interactions by oxidized fatty acids: A natural anti-inflammatory mechanism?

1996 • 50 citations

Regulation of endothelial cell and platelet receptor-ligand binding by the 12- and 15-lipoxygenase monohydroxides, 12-, 15-HETE and 13-HODE

1998 • 34 citations

Nomenclature of lipoxins and related compounds derived from arachidonic acid and eicosapentaenoic acid

1987 • 33 citations

Trout thrombocytes contain 12- but not 5-lipoxygenase activity

1999 • 21 citations

Recent Progress in the Cellular and Molecular Biology of Prostaglandin Synthesis

1998 • 21 citations

Expression Purification and Characterization of Recombinant Human Inducible Prostaglandin G/H Synthase from Baculovirus-Infected Insect Cells

1996 • 20 citations