Epstein–Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2

CDK inhibitors: positive and negative regulators of G1-phase progression

1999 • 6,003 citations

Genome maintenance mechanisms for preventing cancer

2001 • 3,819 citations

Cell Cycle Control and Cancer

1994 • 2,575 citations

Epstein-Barr virus: exploiting the immune system

2001 • 907 citations

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1996 • 746 citations

Deregulated cyclin E induces chromosome instability

1999 • 692 citations

When Checkpoints Fail

1997 • 622 citations

Correlative morphologic and molecular genetic analysis demonstrates three distinct categories of posttransplantation lymphoproliferative disorders

1995 • 596 citations

Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity.

1996 • 562 citations

Mammalian G1- and S-phase checkpoints in response to DNA damage

2001 • 560 citations

Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40

1991 • 554 citations

p21WAF1/Cip1: more than a break to the cell cycle?

2000 • 482 citations

Genetic determinants of p53-induced apoptosis and growth arrest.

1996 • 472 citations

Endoproteolytic Activity of the Proteasome

2003 • 425 citations

Fas ligation induces apoptosis of CD40-activated human B lymphocytes.

1995 • 402 citations

Proteasomal Turnover of p21Cip1 Does Not Require p21Cip1 Ubiquitination

2000 • 391 citations

Ubiquitination of p53 and p21 Is Differentially Affected by Ionizing and UV Radiation

1997 • 316 citations

EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.

1994 • 298 citations

Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis

1999 • 238 citations

A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

2001 • 235 citations

Epstein–Barr virus–associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2

2002 • 223 citations

Proteasome-Dependent Regulation of p21WAF1/CIP1Expression

1996 • 223 citations

Target cells of Epstein-Barr-virus (EBV)-positive post-transplant lymphoproliferative disease: similarities to EBV-positive Hodgkin's lymphoma

2003 • 162 citations

Molecular virology of Epstein–Barr virus

2001 • 148 citations

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19^ARF–p53 signaling

2002 • 143 citations

A model for persistent infection with Epstein-Barr virus: The stealth virus of human B cells

1999 • 137 citations

Long-term cultured CD40-activated B lymphocytes differentiate into plasma cells in response to IL-10 but not IL-4

1995 • 120 citations

Role of genetic and epigenetic changes in Burkitt lymphoma

2002 • 113 citations

DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective.

1995 • 109 citations

Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53.

1995 • 106 citations

Epstein-Barr virus EBNA3C can disrupt multiple cell cycle checkpoints and induce nuclear division divorced from cytokinesis

2000 • 104 citations

Control of Cell Cycle Entry and Apoptosis in B Lymphocytes Infected by Epstein-Barr Virus

1999 • 70 citations

PDK1-dependent activation of atypical PKC leads to degradation of the p21 tumour modifier protein

2002 • 67 citations

Direct and Indirect Regulation of Cytokine and Cell Cycle Proteins by EBNA-2 during Epstein-Barr Virus Infection

2001 • 58 citations

Inactivation of p21 by E1A Leads to the Induction of Apoptosis in DNA-Damaged Cells

2001 • 53 citations

Epstein-Barr Virus Suppresses a G₂/M Checkpoint Activated by Genotoxins

2000 • 51 citations

Convergence of mitogenic and DNA damage signaling in the G1 phase of the cell cycle

2002 • 35 citations

Cell cycle arrest following exposure of EBV‐immortalised B‐cells to gamma irradiation correlates with inhibition of cdk2 activity

1998 • 14 citations