Inhibition of nuclear factor kappa B (NF?B) activity induces nerve growth factor-resistant apoptosis in PC12 cells

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

Programmed Cell Death Induced by Ceramide

1993 • 1,779 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 • 1,524 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Requirement for Phosphatidylinositol-3 Kinase in the Prevention of Apoptosis by Nerve Growth Factor

1995 • 1,400 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

1992 • 1,058 citations

Apoptosis: The Biochemistry and Molecular Biology of Programmed Cell Death*

1993 • 1,005 citations

A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins

1990 • 977 citations

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1993 • 966 citations

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation.

1988 • 909 citations

Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in xenopus ovary

1991 • 836 citations

Checkpoints of dueling dimers foil death wishes

1994 • 806 citations

Induction of Apoptosis by the Low-Affinity NGF Receptor

1993 • 774 citations

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.

1994 • 723 citations

Apoptosis and disease

1993 • 684 citations

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

1994 • 672 citations

The nerve growth factor family of receptors

1992 • 649 citations

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

1994 • 583 citations

Neurotrophic factors and their receptors

1995 • 583 citations

The p75 neurotrophin receptor

1994 • 480 citations

The nerve growth factor: its mode of action on sensory and sympathetic nerve cells.

1966 • 456 citations

Neurotrophin-6 is a new member of the nerve growth factor family

1994 • 404 citations

Regulation of Gene Expression with Double-Stranded Phosphorothioate Oligonucleotides

1990 • 373 citations

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development.

1994 • 371 citations

Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes

1990 • 332 citations

Neurotrophic factor therapy for nervous system degenerative diseases

1994 • 254 citations

Cell death in health and disease: the biology and regulation of apoptosis

1995 • 245 citations

Neurotrophins Induce Sphingomyelin Hydrolysis

1995 • 245 citations

zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro.

1994 • 231 citations

Oligodeoxynucleoside phosphorothioate stability in subcellular extracts, culture media, sera and cerebrospinal fluid

1990 • 220 citations

Ceramide: an endogenous regulator of apoptosis and growth suppresion

1995 • 181 citations

NGF and the Treatment of Alzheimer's Disease

1993 • 140 citations

Nerve growth factor binding in aged rat central nervous system: Effect of acetyl‐l‐carnitine

1988 • 108 citations

The mode of action of nerve growth factor in PC12 cells

1988 • 102 citations

Neurotrophin receptors

1994 • 89 citations

Regulation of NF-κB activity in rat dorsal root ganglia and PC12 cells by tumour necrosis factor and nerve growth factor

1995 • 78 citations

Central glial and neuronal populations display differential sensitivity to ceramide-dependent cell death

1996 • 69 citations

Is p75<sup>NGFR</sup> Involved in Developmental Neural Cell Death?

1994 • 62 citations

Neuronal death, cytoplasmic calcium and internucleosomal DNA fragmentation: evidence for DNA fragments being released from cells

1993 • 61 citations

Ceramide: A Potential Second Messenger in the Nervous System

1995 • 49 citations

Neurotrophic factors and their receptors

1994 • 47 citations

Suppression of p140^trkA Does Not Abolish Nerve Growth Factor‐Mediated Rescue of Serum‐Free PC12 Cells

1996 • 42 citations

Evidence for DNA fragmentation in the CNS of aged Fischer-344 rats

1996 • 39 citations

Transcription factor DNA binding activity in PC12 cells undergoing apoptosis after glucose deprivation

1995 • 37 citations

Nerve growth factor and neuronal cell death

1990 • 36 citations

Cytotoxicity by tumor necrosis factor is mediated by both p55 and p70 receptors

1993 • 28 citations

¹²⁵I‐β‐nerve growth factor binding is reduced in rat brain after stress exposure

1990 • 27 citations

Comparative analysis of the structure and function of TNF-alpha and TNF-beta.

1992 • 17 citations

Kinetics of A-currents in sympathetic preganglionic neurones and glial cells

1995 • 9 citations

Deleted Work

1955 • 0 citations