Neurotrophin receptors

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Purification of a new neurotrophic factor from mammalian brain.

1982 • 1,762 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF

1991 • 1,049 citations

Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain.

1990 • 993 citations

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

1992 • 960 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3

1991 • 940 citations

Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB

1991 • 847 citations

Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in xenopus ovary

1991 • 836 citations

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1991 • 830 citations

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1991 • 819 citations

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1986 • 795 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

Binding of brain-derived neurotrophic factor to the nerve growth factor receptor

1990 • 702 citations

Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

1990 • 700 citations

PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM

1960 • 692 citations

Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease

1992 • 654 citations

Destruction of the sympathetic ganglia in mammals by an antiserum to a nerve-growth protein

1960 • 651 citations

The nerve growth factor family of receptors

1992 • 649 citations

Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity.

1992 • 633 citations

Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells.

1979 • 627 citations

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1989 • 604 citations

Primary structure and biological activity of a novel human neurotrophic factor

1990 • 553 citations

slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.

1990 • 499 citations

Brain-derived neurotrophic factor prevents neuronal death in vivo

1988 • 490 citations

Oncogenes in solid human tumours

1982 • 467 citations

Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor.

1992 • 458 citations

Molecular cloning of a human gene that is a member of the nerve growth factor family.

1990 • 397 citations

Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system

1990 • 375 citations

p140trk mRNA marks NGF-responsive forebrain neurons: Evidence that trk gene expression is induced by NGF

1992 • 371 citations

Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development.

1990 • 342 citations

Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product

1992 • 336 citations

The trk B tyrosine protein kinase is a receptor for neurotrophin-4

1992 • 326 citations

Expression and possible function of nerve growth factor receptors on Schwann cells

1988 • 304 citations

Keeping track of neurotrophin receptors

1991 • 297 citations

Body and brain: A trophic theory of neural connections

1989 • 259 citations

Molecular characteristics of nerve growth factor receptors on PC12 cells.

1985 • 200 citations

Cloning and expression of a cDNA encoding a novel human neurotrophic factor

1990 • 199 citations

The rat trk protooncogene product exhibits properties characteristic of the slow nerve growth factor receptor.

1992 • 198 citations

Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival

1992 • 195 citations

A novel modular mosaic of cell adhesion motifs in the extracellular domains of the neurogenic trk and trkB tyrosine kinase receptors.

1991 • 193 citations

Dependence of Kidney Morphogenesis on the Expression of Nerve Growth Factor Receptor

1991 • 184 citations

The trk family of tyrosine protein kinase receptors

1991 • 170 citations

Molecular investigations on the high-affinity nerve growth factor receptor

1991 • 154 citations

Binding characteristics of brain-derived neurotrophic factor to its receptors on neurons from the chick embryo

1988 • 142 citations

Dimeric structure and conformational stability of brain-derived neurotrophic factor and neurotrophin-3

1992 • 80 citations

Neuroantibodies: molecular cloning of a monoclonal antibody against substance P for expression in the central nervous system.

1991 • 31 citations

Analytical purification of the slow, high affinity NGF receptor: Identification of a novel 135 kd polypeptide

1991 • 29 citations

The highs and lows of an NGF receptor

1992 • 11 citations