Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach.

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

Host Defense Mechanisms Triggered by Microbial Lipoproteins Through Toll-Like Receptors

1999 • 1,679 citations

Lack of Acidification inMycobacteriumPhagosomes Produced by Exclusion of the Vesicular Proton-ATPase

1994 • 1,289 citations

Selective Expression of the Eotaxin Receptor CCR3 by Human T Helper 2 Cells

1997 • 1,073 citations

Hsp27 negatively regulates cell death by interacting with cytochrome c

2000 • 972 citations

Induction of Manganous Superoxide Dismutase by Tumor Necrosis Factor: Possible Protective Mechanism

1988 • 933 citations

Human Toll-Like Receptors Mediate Cellular Activation by Mycobacterium tuberculosis

1999 • 813 citations

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils.

1996 • 626 citations

Essential Role for Cholesterol in Entry of Mycobacteria into Macrophages

2000 • 610 citations

Macrophage phagocytosis of virulent but not attenuated strains of Mycobacterium tuberculosis is mediated by mannose receptors in addition to complement receptors.

1993 • 603 citations

A Coat Protein on Phagosomes Involved in the Intracellular Survival of Mycobacteria

1999 • 573 citations

Phagosome-lysosome interactions in cultured macrophages infected with virulent tubercle bacilli. Reversal of the usual nonfusion pattern and observations on bacterial survival.

1975 • 528 citations

High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines.

1997 • 489 citations

Mycobacterium-containing phagosomes are accessible to early endosomes and reflect a transitional state in normal phagosome biogenesis.

1996 • 357 citations

The proton-ATPase of bacteria and mitochondria

1983 • 346 citations

Acid tolerance, proton permeabilities, and membrane ATPases of oral streptococci

1986 • 321 citations

Cc Chemokine Receptor (Ccr)3/Eotaxin Is Followed by Ccr4/Monocyte-Derived Chemokine in Mediating Pulmonary T Helper Lymphocyte Type 2 Recruitment after Serial Antigen Challenge in Vivo

2000 • 309 citations

Improved and simplified in‐gel sample application using reswelling of dry immobilized pH gradients

1997 • 309 citations

Mycobacterium tuberculosis CDC1551 Induces a More Vigorous Host Response In Vivo and In Vitro, But Is Not More Virulent Than Other Clinical Isolates

1999 • 300 citations

Improvement and simplification of low‐background silver staining of proteins by using sodium dithionite

1988 • 297 citations

Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils

1997 • 292 citations

Influence of Polymorphism in the Genes for the Interleukin (IL)-1 Receptor Antagonist and IL-1β on Tuberculosis

1999 • 288 citations

Complement receptor-mediated uptake and tumor necrosis factor-alpha-mediated growth inhibition of Mycobacterium tuberculosis by human alveolar macrophages.

1994 • 260 citations

Chemokines Induced by Infection of Mononuclear Phagocytes with Mycobacteria and Present in Lung Alveoli during Active Pulmonary Tuberculosis

1998 • 231 citations

Macrophage oxygen-dependent antimicrobial activity. III. Enhanced oxidative metabolism as an expression of macrophage activation.

1980 • 223 citations

Enhanced Expression of Eotaxin and CCR3 in Atopic Dermatitis

1999 • 217 citations

Salmonella typhimuriumInfection and Lipopolysaccharide Stimulation Induce Similar Changes in Macrophage Gene Expression

2000 • 212 citations

TNF-alpha and IL-10 modulate the induction of apoptosis by virulent Mycobacterium tuberculosis in murine macrophages.

1999 • 204 citations

Selective receptor blockade during phagocytosis does not alter the survival and growth of Mycobacterium tuberculosis in human macrophages.

1996 • 198 citations

Sequestration From Immune CD4 ⁺ T Cells of Mycobacteria Growing in Human Macrophages

1993 • 194 citations

A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis

1997 • 188 citations

Chemokine Production by a Human Alveolar Epithelial Cell Line in Response toMycobacterium tuberculosis

1998 • 186 citations

Streptococcal cytoplasmic pH is regulated by changes in amount and activity of a proton-translocating ATPase.

1986 • 168 citations

Pulmonary epithelial cells are a source of IL-8 in the response to Mycobacterium tuberculosis: essential role of IL-1 from infected monocytes in a NF-kappa B-dependent network.

1999 • 149 citations

Chemokine secretion by human polymorphonuclear granulocytes after stimulation with Mycobacterium tuberculosis and lipoarabinomannan

1997 • 142 citations

Differential Expression and Cross-Regulatory Function of RANTES During Mycobacterial (Type 1) and Schistosomal (Type 2) Antigen-Elicited Granulomatous Inflammation

1999 • 136 citations

The global tuberculosis situation and the new control strategy of the World Health Organization. 1991.

2001 • 126 citations

Eotaxin: from an eosinophilic chemokine to a major regulator of allergic reactions

1999 • 124 citations

Monitoring Cellular Responses to Listeria monocytogenes with Oligonucleotide Arrays

2000 • 123 citations

Possible Involvement of Matrix Metalloproteinase-9 in Langerhans Cell Migration and Maturation

1999 • 123 citations

Defective antigen presentation by Mycobacterium tuberculosis-infected monocytes

1994 • 117 citations

Mycobacteria-macrophage interactions. Macrophage phenotype determines the nonopsonic binding of Mycobacterium tuberculosis to murine macrophages.

1993 • 104 citations

Expression of Chemokines and Induction of Rapid Cell Death in Human Blood Neutrophils by Mycobacterium tuberculosis

1998 • 99 citations

Macrophage oxygen-dependent antimicrobial activity. IV. Role of endogenous scavengers of oxygen intermediates.

1980 • 89 citations

Interleukin-8 Induces Lymphocyte Chemotaxis into the Pleural Space

1999 • 84 citations

Langerhans’ cells produce type IV collagenase (MMP‐9) following epicutaneous stimulation with haptens

1997 • 81 citations

STRUCTURE AND FUNCTION OF H⁺‐ATPase: WHAT WE HAVE LEARNED FROM Escherichia coli H⁺‐ATPase*

1982 • 76 citations

Gene structure of Enterococcus hirae (Streptococcus faecalis) F1F0-ATPase, which functions as a regulator of cytoplasmic pH

1992 • 63 citations

Rapid priming of human monocytes by human hematopoietic growth factors: granulocyte-macrophage colony-stimulating factor (CSF), macrophage-CSF, and interleukin-3 selectively enhance superoxide release triggered by receptor-mediated agonists

1992 • 61 citations

A Macrophage Invasion Mechanism for Mycobacteria Implicating the Extracellular Domain of Cd43

2000 • 56 citations

Increases in eotaxin‐positive cells in induced sputum from atopic asthmatic subjects after inhalational allergen challenge

1999 • 38 citations

Phagocytosis of mycobacterium tuberculosis or particulate stimuli by human monocytic cells induces equivalent monocyte chemotactic protein-1 gene expression

1993 • 36 citations

Analysis of F1F0-ATPase from Helicobacter pylori

1997 • 29 citations

Differential cytokine gene expression and secretion after phagocytosis by a human monocytic cell line of Toxoplasma gondii compared with Mycobacterium tuberculosis

1993 • 24 citations

Characterization of eosinophils and detection of eotaxin in skin chamber fluid after challenge with relevant allergen in patients with mild asthma

1999 • 11 citations

HIV Type 1 Infection of Human Macrophages Induces an Upregulation of Manganese Superoxide Dismutase Gene That May Protect Cells from Death

1998 • 7 citations

Deleted Work

1955 • 0 citations