Infection and Spread of Alphaherpesviruses in the Nervous System

Wavelength mutations and posttranslational autoxidation of green fluorescent protein.

1994 • 1,773 citations

Textbook of Pediatric Infectious Diseases

2013 • 1,729 citations

The Role of the Hippocampus in Feedback Regulation of the Hypothalamic-Pituitary-Adrenocortical Axis*

1991 • 1,690 citations

Kinesin and Dynein Superfamily Proteins and the Mechanism of Organelle Transport

1998 • 1,634 citations

The Fine Structure of the Nervous System: Neurons and Their Supporting Cells

1991 • 1,522 citations

The distribution of tau in the mammalian central nervous system.

1985 • 1,518 citations

The Complete DNA Sequence of Varicella-Zoster Virus

1986 • 1,425 citations

Severe Herpesvirus Infections in an Adolescent without Natural Killer Cells

1989 • 1,251 citations

ER-to-Golgi transport visualized in living cells

1997 • 1,169 citations

Herpes Simplex Virus-1 Entry into Cells Mediated by a Novel Member of the TNF/NGF Receptor Family

1996 • 1,068 citations

A Structural Scaffolding of Intermediate Filaments in Health and Disease

1998 • 1,003 citations

Genital Herpes Simplex Virus Infections: Clinical Manifestations, Course, and Complications

1983 • 921 citations

Initial interaction of herpes simplex virus with cells is binding to heparan sulfate

1989 • 913 citations

Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone.

1988 • 851 citations

Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomas

1995 • 800 citations

Herpes simplex virus turns off the TAP to evade host immunity

1995 • 736 citations

The γ ₁ 34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1α to dephosphorylate the α subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase

1997 • 734 citations

Mapping of Herpes Simplex Virus-1 Neurovirulence to γ ₁ 34.5, a Gene Nonessential for Growth in Culture

1990 • 705 citations

Microtubule-mediated Transport of Incoming Herpes Simplex Virus 1 Capsids to the Nucleus

1997 • 692 citations

Adenine Arabinoside Therapy of Biopsy-Proved Herpes Simplex Encephalitis

1977 • 691 citations

Central Command Neurons of the Sympathetic Nervous System: Basis of the Fight-or-Flight Response

1995 • 683 citations

A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells

1996 • 624 citations

Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity

1990 • 618 citations

Infections of the Central Nervous System

1991 • 603 citations

Multiple Output Channels in the Basal Ganglia

1993 • 596 citations

A general pattern of CNS innervation of the sympathetic outflow demonstrated by transneuronal pseudorabies viral infections

1989 • 574 citations

Vibrio cholerae produces a second enterotoxin, which affects intestinal tight junctions.

1991 • 570 citations

A herpes simplex virus mutant in which glycoprotein D sequences are replaced by beta-galactosidase sequences binds to but is unable to penetrate into cells

1988 • 514 citations

Visualization of ER-to-Golgi Transport in Living Cells Reveals a Sequential Mode of Action for COPII and COPI

1997 • 510 citations

Molecular Mimicry by Herpes Simplex Virus-Type 1: Autoimmune Disease After Viral Infection

1998 • 505 citations

CNS cell groups regulating the sympathetic outflow to adrenal gland as revealed by transneuronal cell body labelling with pseudorabies virus

1989 • 484 citations

Molecular Phylogeny and Evolutionary Timescale for the Family of Mammalian Herpesviruses

1995 • 484 citations

Brainstem network controlling descending drive to phrenic motoneurons in rat

1994 • 469 citations

Role of glycoprotein B of herpes simplex virus type 1 in viral entry and cell fusion

1988 • 468 citations

Herpes Simplex Encephalitis

1986 • 464 citations

Pathogenesis of Herpetic Neuritis and Ganglionitis in Mice: Evidence for Intra-Axonal Transport of Infection

1973 • 456 citations

Intrauterine Infection with Varicella-Zoster Virus after Maternal Varicella

1986 • 453 citations

Polarity of Epithelial and Neuronal Cells

1992 • 435 citations

Optimized Codon Usage and Chromophore Mutations Provide Enhanced Sensitivity with the Green Fluorescent Protein

1996 • 435 citations

Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture

1990 • 425 citations

Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted

1992 • 401 citations

Glycoprotein C of herpes simplex virus 1 acts as a receptor for the C3b complement component on infected cells

1984 • 384 citations

Herpes Simplex Virus Encephalitis: Laboratory Evaluations and Their Diagnostic Significance

1982 • 382 citations

Assembly of vaccinia virus: the second wrapping cisterna is derived from the trans Golgi network

1994 • 376 citations

High molecular weight microtubule-associated proteins are preferentially associated with dendritic microtubules in brain.

1981 • 363 citations

Neuronal Circuit Regulation of the Hypothalamo-Pituitary-Adrenocortical Stress Axis

1996 • 358 citations

The Genome Sequence of Herpes Simplex Virus Type 2

1998 • 356 citations

Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47.

1996 • 350 citations

Risk of Recurrence after First Episodes of Genital Herpes

1981 • 348 citations

The retinohypothalamic tract originates from a distinct subset of retinal ganglion cells

1995 • 345 citations

Genetics of natural resistance to herpesvirus infections in mice

1975 • 342 citations

Neurotropic properties of pseudorabies virus: uptake and transneuronal passage in the rat central nervous system

1990 • 337 citations

The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in mice

1978 • 337 citations

Herpes simplex virus glycoproteins E and I facilitate cell-to-cell spread in vivo and across junctions of cultured cells

1994 • 335 citations

Changing Presentation of Herpes Simplex Virus Infection in Neonates

1988 • 332 citations

Principles of Neural Science, 3rd ed

1993 • 328 citations

Herpes simplex virus immunoglobulin G Fc receptor activity depends on a complex of two viral glycoproteins, gE and gI

1988 • 328 citations

Pseudorabies virus infection of the rat central nervous system: ultrastructural characterization of viral replication, transport, and pathogenesis

1993 • 327 citations

Two activators of microtubule-based vesicle transport.

1991 • 325 citations

A mutant herpes simplex virus type 1 unable to express glycoprotein L cannot enter cells, and its particles lack glycoprotein H

1993 • 322 citations

Methods in molecular genetics

1995 • 319 citations

Glycoproteins Specified by Herpes Simplex Viruses

1985 • 314 citations

Red-Shifted Excitation Mutants of the Green Fluorescent Protein

1995 • 306 citations

Cholesterol and vesicular stomatitis virus G protein take separate routes from the endoplasmic reticulum to the plasma membrane.

1990 • 304 citations

The Golgi apparatus: 100 years of progress and controversy

1998 • 303 citations

Cytotoxicity of a replication-defective mutant of herpes simplex virus type 1

1992 • 296 citations

Assembly of vaccinia virus: role of the intermediate compartment between the endoplasmic reticulum and the Golgi stacks.

1993 • 294 citations

Input to the primate frontal eye field from the substantia nigra, superior colliculus, and dentate nucleus demonstrated by transneuronal transport

1994 • 290 citations

Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of herpes simplex virus 1.

1995 • 283 citations

The morphology of herpes virus

1960 • 283 citations

Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry

1997 • 282 citations

Macrophages and Age-Dependent Resistance to Herpes Simplex Virus in Mice

1970 • 282 citations

Products of endocytosis and autophagy are retrieved from axons by regulated retrograde organelle transport.

1993 • 281 citations

Human herpesviruses: a consideration of the latent state

1989 • 279 citations

Polarized distribution of viral envelope proteins in the plasma membrane of infected epithelial cells

1980 • 273 citations

The herpes simplex virus 1 protein kinase U _S 3 is required for protection from apoptosis induced by the virus

1997 • 271 citations

Progeny vaccinia and human cytomegalovirus particles utilize early endosomal cisternae for their envelopes.

1993 • 267 citations

THE PATHOGENESIS OF HERPES VIRUS ENCEPHALITIS

1964 • 263 citations

Localization of proteins to the Golgi apparatus

1998 • 257 citations

Monensin inhibits the processing of herpes simplex virus glycoproteins, their transport to the cell surface, and the egress of virions from infected cells

1982 • 257 citations

Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence

1991 • 256 citations

mRNA Localization in Neurons: A Multipurpose Mechanism?

1997 • 248 citations

An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoproteins gG, gE, gI or the putative gJ

1994 • 247 citations

Anti-CD8 impairs clearance of herpes simplex virus from the nervous system: implications for the fate of virally infected neurons.

1992 • 246 citations

Herpes simplex virus 1 mutant deleted in the alpha 22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in mice

1985 • 243 citations

Viruses as transneuronal tracers

1990 • 236 citations

Pseudorabies virus: a highly specific transneuronal cell body marker in the sympathetic nervous system

1990 • 234 citations

Transneuronal Labeling of a Nociceptive Pathway, the Spino-(Trigemino-)Parabrachio-Amygdaloid, in the Rat

1997 • 229 citations

Transneuronal labeling of CNS neuropeptide and monoamine neurons after pseudorabies virus injections into the stellate ganglion

1995 • 227 citations

Perturbation of the morphology of the trans-Golgi network following Brefeldin A treatment: redistribution of a TGN-specific integral membrane protein, TGN38.

1992 • 226 citations

Comparative Neurovirulence of Herpes Simplex Virus Type 1 Strains After Peripheral or Intracerebral Inoculation of BALB/c Mice

1983 • 226 citations

Electron Microscopy of Herpes Simplex Virus

1968 • 224 citations

Direction of transneuronal transport of herpes simplex virus 1 in the primate motor system is strain-dependent.

1991 • 221 citations

Herpesvirus Infections of the Human Central Nervous System

1967 • 219 citations

Intracellular transport of newly synthesized varicella-zoster virus: final envelopment in the trans-Golgi network

1994 • 213 citations

Pseudorabies virus envelope glycoprotein gI influences both neurotropism and virulence during infection of the rat visual system

1992 • 212 citations

Peripheral and central pathways regulating the kidney: a study using pseudorabies virus

1993 • 209 citations

Two α-herpesvirus strains are transported differentially in the rodent visual system

1991 • 208 citations

Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virus

1988 • 204 citations

Pseudorabies virus glycoproteins gII and gp50 are essential for virus penetration

1991 • 203 citations

CNS projections to the pterygopalatine parasympathetic preganglionic neurons in the rat: a retrograde transneuronal viral cell body labeling study

1990 • 202 citations

Herpes simplex virus 1 gamma(1)34.5 gene function, which blocks the host response to infection, maps in the homologous domain of the genes expressed during growth arrest and DNA damage.

1994 • 201 citations

DNA Restriction-Enzyme Analysis of Herpes Simplex Virus Isolates Obtained from Patients with Encephalitis

1982 • 200 citations

Identification of a novel herpes simplex virus type 1-induced glycoprotein which complexes with gE and binds immunoglobulin

1987 • 200 citations

Virulence of and establishment of latency by genetically engineered deletion mutants of herpes simplex virus I

1988 • 199 citations

Glycoproteins E and I facilitate neuron-to-neuron spread of herpes simplex virus

1995 • 198 citations

Axonal transport of herpes simplex virions to epidermal cells: evidence for a specialized mode of virus transport and assembly.

1994 • 197 citations

DIFFERENCE BETWEEN HERPES SIMPLEX VIRUS TYPE I AND TYPE 2 NEONATAL ENCEPHALITIS IN NEUROLOGICAL OUTCOME

1988 • 196 citations

Retrograde transneuronal transfer of Herpes simplex virus type 1 (HSV 1) from motoneurones

1987 • 195 citations

Structure and assembly of herpesviruses

1993 • 193 citations

Central nervous system innervation of the penis as revealed by the transneuronal transport of pseudorabies virus

1993 • 193 citations

Characterization of the multisynaptic neuronal control of the rat pineal gland using viral transneuronal tracing

1998 • 192 citations

Cloning of a gene (zot) encoding a new toxin produced by Vibrio cholerae

1992 • 191 citations

Spatiotemporal responses of astrocytes, ramified microglia, and brain macrophages to central neuronal infection with pseudorabies virus

1993 • 191 citations

Protein Synthesis within Dendrites: Glycosylation of Newly Synthesized Proteins in Dendrites of Hippocampal Neurons in Culture

1996 • 189 citations

Infected Cell Protein (ICP)47 Enhances Herpes Simplex Virus Neurovirulence by Blocking the CD8+ T Cell Response

1998 • 188 citations

Identification and characterization of a novel non-infectious herpes simplex virus-related particle

1991 • 187 citations

DEVELOPMENT AND APPLICATION OF HERPES SIMPLEX VIRUS VECTORS FOR HUMAN GENE THERAPY

1995 • 187 citations

Ultrastructural analysis of the replication cycle of pseudorabies virus in cell culture: a reassessment

1997 • 187 citations

Spread of herpes simplex virus in peripheral nerves

1971 • 186 citations

Excretion of Non-infectious Virus Particles Lacking Glycoprotein H by a Temperature-sensitive Mutant of Herpes Simplex Virus Type 1: Evidence that gH Is Essential for Virion Infectivity

1988 • 185 citations

Pseudorabies virus envelope glycoproteins gp50 and gII are essential for virus penetration, but only gII is involved in membrane fusion

1992 • 183 citations

Effect of brefeldin A on alphaherpesvirus membrane protein glycosylation and virus egress

1991 • 183 citations

Central neuronal circuit innervating the rat heart defined by transneuronal transport of pseudorabies virus

1995 • 180 citations

Interconnected Parallel Circuits between Rat Nucleus Accumbens and Thalamus Revealed by Retrograde Transynaptic Transport of Pseudorabies Virus

1997 • 178 citations

Transneuronal labeling of neurons in the adult rat brainstem and spinal cord after injection of pseudorabies virus into the urethra

1995 • 175 citations

Transneuronal Transfer of Herpes Virus from Peripheral Nerves to Cortex and Brainstem

1989 • 175 citations

Herpes-Type Virus of the Frog Renal Adenocarcinoma

1969 • 173 citations

Gene Transfer to Neurons Using Herpes Simplex Virus-Based Vectors

1996 • 171 citations

CNS innervation of airway-related parasympathetic preganglionic neurons: a transneuronal labeling study using pseudorabies virus

1993 • 171 citations

Innervation of the Heart and Its Central Medullary Origin Defined by Viral Tracing

1994 • 169 citations

CNS sites involved in sympathetic and parasympathetic control of the pancreas: a viral tracing study

1997 • 166 citations

Contribution of single genes within the unique short region of Aujeszky's disease virus (suid herpesvirus type 1) to virulence, pathogenesis and immunogenicity

1992 • 161 citations

The pseudorabies virus gII gene is closely related to the gB glycoprotein gene of herpes simplex virus

1987 • 160 citations

Specific pseudorabies virus infection of the rat visual system requires both gI and gp63 glycoproteins

1993 • 159 citations

The UL20 gene of herpes simplex virus 1 encodes a function necessary for viral egress

1991 • 158 citations

VP16 interacts via its activation domain with VP22, a tegument protein of herpes simplex virus, and is relocated to a novel macromolecular assembly in coexpressing cells

1995 • 158 citations

Herpes simplex virus infection and propagation in a mouse L cell mutant lacking heparan sulfate proteoglycans

1993 • 156 citations

Herpesvirus Envelopment

1968 • 156 citations

ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell cultures

1994 • 152 citations

Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhs

1994 • 151 citations

Neuroanatomy of Cardiac Activity‐regulating Circuitry: A Transneuronal Retrograde Viral Labelling Study in the Rat

1996 • 149 citations

Ribonucleotide Reductase Encoded by Herpes Simplex Virus Is a Determinant of the Pathogenicity of the Virus in Mice and a Valid Antiviral Target

1988 • 147 citations

Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors.

1997 • 147 citations

Central nervous system neurons labelled following the injection of pseudorabies virus into the rat urinary bladder

1992 • 146 citations

Herpes simplex virus infection of the human sensory neuron

1988 • 145 citations

Complement component C3b binds directly to purified glycoprotein C of herpes simplex virus types 1 and 2

1987 • 145 citations

The organization of the endoplasmic reticulum and the intermediate compartment in cultured rat hippocampal neurons.

1995 • 144 citations

Herpes simplex virus type 1 Fc receptor protects infected cells from antibody-dependent cellular cytotoxicity

1991 • 144 citations

Transneuronal labeling of spinal interneurons and sympathetic preganglionic neurons after pseudorabies virus injections in the rat medial gastrocnemius muscle

1992 • 143 citations

CNS cell groups involved in the control of the ischiocavernosus and bulbospongiosus muscles: A transneuronal tracing study using pseudorabies virus

1996 • 143 citations

Sequential isolation of proteoglycan synthesis mutants by using herpes simplex virus as a selective agent: evidence for a proteoglycan-independent virus entry pathway

1995 • 141 citations

Uptake and Transport of Herpes Simplex Virus in Neurites of Rat Dorsal Root Ganglia Cells in Culture

1984 • 140 citations

Endocytosis and recycling of varicella-zoster virus Fc receptor glycoprotein gE: internalization mediated by a YXXL motif in the cytoplasmic tail

1997 • 139 citations

Neurons in the rat brain and spinal cord labeled after pseudorabies virus injected into the external urethral sphincter

1996 • 138 citations

Neuron to neuron transmission of herpes simplex virus

1982 • 136 citations

Herpes simplex virus type 1 dUTPase mutants are attenuated for neurovirulence, neuroinvasiveness, and reactivation from latency

1992 • 134 citations

Neuronal and transneuronal tracing in the trigeminal system of the rat using the herpes virus suis

1983 • 134 citations

Cell biology of viruses that assemble along the biosynthetic pathway

1992 • 132 citations

Two Avirulent Herpes Simplex Viruses Generate Lethal Recombinants in Vivo

1986 • 131 citations

Rapid Identification of Nonessential Genes of Herpes Simplex Virus Type 1 by Tn5 Mutagenesis

1987 • 130 citations

Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking

1997 • 129 citations

Receptor properties of two varicella-zoster virus glycoproteins, gpI and gpIV, homologous to herpes simplex virus gE and gI

1992 • 129 citations

Fragmentation and dispersal of Golgi proteins and redistribution of glycoproteins and glycolipids processed through the Golgi apparatus after infection with herpes simplex virus 1.

1993 • 128 citations

Physical location of a herpes simplex virus type-1 gene function(s) specifically associated with a 10 million-fold increase in HSV neurovirulence

1983 • 128 citations

An endoplasmic reticulum-retained herpes simplex virus glycoprotein H is absent from secreted virions: evidence for reenvelopment during egress

1996 • 127 citations

Neural spread of herpes simplex virus types 1 and 2 in mice after corneal or subcutaneous (footpad) inoculation

1978 • 127 citations

Adsorption of Sensitized Sheep Erythrocytes to HeLa Cells infected with Herpes Simplex Virus

1964 • 127 citations

Herpes Simplex Virus Type 2 ICP47 Inhibits Human TAP but Not Mouse TAP

1998 • 126 citations

Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb

1993 • 126 citations

Neuritic Transport of Herpes Simplex Virus in Rat Sensory Neurons in vitro. Effects of Substances Interacting with Microtubular Function and Axonal Flow [Nocodazole, Taxol and Erythro-9-3-(2-hydroxynonyl)adenine]

1986 • 125 citations

Redistribution of microtubules and Golgi apparatus in herpes simplex virus-infected cells and their role in viral exocytosis

1995 • 123 citations

Oligomeric structure of glycoproteins in herpes simplex virus type 1

1996 • 123 citations

Pathogenesis of Herpetic Encephalitis in Mice after Ophthalmic Inoculation

1974 • 122 citations

The Phospholipid Composition of Extracellular Herpes Simplex Virions Differs from That of Host Cell Nuclei

1994 • 122 citations

Herpes simplex encephalitis

1983 • 122 citations

Deletions in the genomes of pseudorabies virus vaccine strains and existence of four isomers of the genomes

1984 • 121 citations

Functional regions and structural features of the gB glycoprotein of herpes simplex virus type 1

1988 • 121 citations

Complex between glycoproteins gI and gp63 of pseudorabies virus: its effect on virus replication

1988 • 120 citations

Role of Envelope Protein gE Endocytosis in the Pseudorabies Virus Life Cycle

1998 • 119 citations

Targeting of glycoprotein I (gE) of varicella-zoster virus to the trans-Golgi network by an AYRV sequence and an acidic amino acid-rich patch in the cytosolic domain of the molecule

1996 • 116 citations

Specificity of pseudorabies virus as a retrograde marker of sympathetic preganglionic neurons: implications for transneuronal labeling studies

1993 • 115 citations

An Outbreak of Herpes Simplex among Wrestlers (Herpes gladiatorum)

1964 • 115 citations

Herpes Simplex Virus Infections of the Central Nervous System

1991 • 115 citations

Regulation of the cell cycle by viral oncoproteins

1995 • 115 citations

Development of polarity in cerebellar granule neurons

1997 • 114 citations

Microtubules and axonal growth

1997 • 113 citations

The Us9 Gene Product of Pseudorabies Virus, an Alphaherpesvirus, Is a Phosphorylated, Tail-Anchored Type II Membrane Protein

1998 • 112 citations

Concerning the egress of herpes simplex virus from infected cells: Electron and light microscope observations

1969 • 112 citations

Forebrain parasympathetic control of heart activity: retrograde transneuronal viral labeling in rats

1997 • 112 citations

Study on the propagation of Herpes simplex virus (type 2) into the brain after intraocular injection

1974 • 111 citations

Genetic basis of the neurovirulence of pseudorabies virus

1984 • 111 citations

Glycoprotein gI of pseudorabies virus promotes cell fusion and virus spread via direct cell-to-cell transmission

1992 • 110 citations

The neuronal endoplasmic reticulum: Its cytochemistry and contribution to the endomembrane system. II. Axons and terminals

1984 • 110 citations

Anterograde tracing of trigeminal afferent pathways from the murine tooth pulp to cortex using herpes simplex virus type 1

1995 • 107 citations

Infections of the Central Nervous System

1992 • 106 citations

Central nervous system neurons infected by pseudorabies virus injected into the rat urinary bladder following unilateral transection of the pelvic nerve

1995 • 106 citations

CNS cell groups projecting to pancreatic parasympathetic preganglionic neurons

1993 • 106 citations

Genome location and identification of functions defective in the Bartha vaccine strain of pseudorabies virus

1987 • 103 citations

Immune evasion properties of herpes simplex virus type 1 glycoprotein gC

1996 • 103 citations

Brain stem localization of rodent esophageal premotor neurons revealed by transneuronal passage of pseudorabies virus

1994 • 102 citations

Inflammatory effects of gene transfer into the CNS with defective HSV-1 vectors.

1994 • 101 citations

CNS monoamine cell groups projecting to pancreatic vagal motor neurons: a transneuronal labeling study using pseudorabies virus

1994 • 101 citations

Origin of unenveloped capsids in the cytoplasm of cells infected with herpes simplex virus 1

1991 • 100 citations

Functional and molecular analyses of the avirulent wild-type herpes simplex virus type 1 strain KOS

1986 • 100 citations

Role of envelope glycoproteins gI, gp63 and gIII in the invasion and spread of Aujeszky's disease virus in the olfactory nervous pathway of the pig

1994 • 99 citations

Study of herpes simplex virus maturation during a synchronous wave of assembly

1997 • 99 citations

Characterization of pseudorabies virus mutants expressing carboxy-terminal truncations of gE: evidence for envelope incorporation, virulence, and neurotropism domains

1997 • 99 citations

Herpes simplex virus envelopment and maturation studied by fracture label

1992 • 98 citations

Biological characterization of a herpes simplex virus intertypic recombinant which is completely and specifically non-neurovirulent

1983 • 98 citations

CNS cell groups projecting to the submandibular parasympathetic preganglionic neurons in the rat: a retrograde transneuronal viral cell body labeling study

1992 • 98 citations

Neural spread of herpes simplex virus after anterior chamber inoculation.

1991 • 97 citations

Neurovirulence of pseudorabies virus.

1995 • 96 citations

Protocols for gene transfer in neuroscience : towards gene therapy of neurological disorders

1996 • 96 citations

Molecular and biological characterization of a herpes simplex virus type 1 (HSV-1) neuroinvasiveness gene.

1990 • 95 citations

Role of a structural glycoprotein of pseudorabies in virus virulence

1987 • 94 citations

Expression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript

1994 • 93 citations

Smooth Endoplasmic Reticulum and Axonal Transport

1980 • 93 citations

Retrieval of human cytomegalovirus glycoprotein B from the infected cell surface for virus envelopment

1996 • 92 citations

Evolutionary relationships of virion glycoprotein genes in the S regions of alphaherpesvirus genomes

1990 • 91 citations

Viral vectors : gene therapy and neuroscience applications

1995 • 91 citations

Glycoprotein D of herpes simplex virus encodes a domain which precludes penetration of cells expressing the glycoprotein by superinfecting herpes simplex virus

1990 • 90 citations

Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2

1994 • 89 citations

Anterograde, transneuronal transport of herpes simplex virus type 1 strain H129 in the murine visual system

1996 • 88 citations

A glycoprotein gX-β-galactosidase fusion gene as insertional marker for rapid identification of pseudorabies virus mutants

1990 • 88 citations

The Axis-Cylinders of Peripheral Nerves as Portals of Entry to the Central Nervous System for the Virus of Herpes Simplex in Experimentally Infected Rabbits.

1925 • 88 citations

Construction of a US3 lacZ insertion mutant of herpes simplex virus type 2 and characterization of its phenotype in vitro and in vivo

1992 • 87 citations

Intraaxonal transport of Herpes simplex virus in the rat central nervous system

1977 • 86 citations

Role of cytoplasmic vacuoles in varicella-zoster virus glycoprotein trafficking and virion envelopment

1988 • 86 citations

Attachment of Herpes Simplex Virus to Neurons and Glial Cells

1978 • 86 citations

Microtubule polarity in the peripheral processes of trigeminal ganglion cells: relevance for the retrograde transport of herpes simplex virus

1994 • 86 citations

Morphological studies of the neural spread of herpes simplex virus to the central nervous system

1970 • 85 citations

Deletion of Glycoprotein gE Reduces the Propagation of Pseudorabies Virus in the Nervous System of Mice after Intranasal Inoculation

1996 • 85 citations

Role of pseudorabies virus glycoprotein gI in virus release from infected cells

1987 • 84 citations

Production of Encephalitis Restricted to the Temporal Lobes by Experimental Reactivation of Herpes Simplex Virus

1986 • 83 citations

Comparative pathobiology of viral diseases

1985 • 83 citations

Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene

1986 • 82 citations

Unravelling Golgi membrane traffic with green fluorescent protein chimeras

1998 • 82 citations

Envelope glycoprotein gp50 of pseudorabies virus is essential for virus entry but is not required for viral spread in mice

1993 • 82 citations

The Role of Immune Mechanisms in Control of Herpes Simplex Virus Infection of the Peripheral Nervous System

1992 • 80 citations

The central neural pathways involved in micturition in the neonatal rat as revealed by the injection of pseudorabies virus into the urinary bladder

1997 • 80 citations

Transneuronal pathways to the vestibulocerebellum

1996 • 80 citations

Golgi-like, transneuronal retrograde labelling with CNS injections of herpes simplex virus type

1989 • 80 citations

The Pathogenesis of Pseudorabies in Mice following Peripheral Inoculation

1974 • 79 citations

The distribution of herpes simplex type 1 antigen in mouse central nervous system after different routes of inoculation

1983 • 79 citations

Herpes simplex virus type I infection of the CNS induces major histocompatibility complex antigen expression on rat microglia

1990 • 79 citations

Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms

1997 • 78 citations

Varicella-zoster virus glycoprotein gpI/gpIV receptor: expression, complex formation, and antigenicity within the vaccinia virus-T7 RNA polymerase transfection system

1993 • 77 citations

Propagation of Pseudorabies Virus in the Nervous System of the Mouse after Intranasal Inoculation

1994 • 77 citations

Glycoprotein gE-negative Pseudorabies Virus has a Reduced Capability to Infect Second- and third-order Neurons of the Olfactory and Trigeminal Routes in the Porcine Central Nervous System

1994 • 76 citations

Open reading frame P--a herpes simplex virus gene repressed during productive infection encodes a protein that binds a splicing factor and reduces synthesis of viral proteins made from spliced mRNA.

1996 • 75 citations

Herpes Simplex and Pseudorabies Viruses.

1969 • 75 citations

Brefeldin A arrests the maturation and egress of herpes simplex virus particles during infection

1991 • 74 citations

Transneuronal transport of herpes simplex virus from the cervical vagus to brain neurons with axonal inputs to central vagal sensory nuclei in the rat

1991 • 74 citations

Complementary lethal invasion of the central nervous system by nonneuroinvasive herpes simplex virus types 1 and 2

1991 • 74 citations

Herpes Simplex Encephalitis in the Temporal Cortex and Limbic System after Trigeminal Nerve Inoculation

1994 • 74 citations

The herpes simplex virus ribonucleotide reductase is required for ocular virulence

1991 • 72 citations

Selective Destruction of Gliomas in Immunocompetent Rats by Thymidine Kinase-Defective Herpes Simplex Virus Type 1

1994 • 72 citations

Herpes simplex virus infections of women and their offspring: implications for a developed society.

1994 • 71 citations

Central nervous system neurons identified after injection of pseudorabies virus into the rat clitoris

1995 • 71 citations

Different Patterns of Neuronal Infection after Intracerebral Injection of Two Strains of Pseudorabies Virus

1998 • 71 citations

Delection of the herpes simplex virus type 1 ribonucleotide reductase gene alters virulence and latency in vivo

1992 • 71 citations

Viral Pathogens and ImmunityMutations Affecting the UL21 Gene Contribute to Avirulence of Pseudorabies Virus Vaccine Strain Bartha

1995 • 70 citations

Infection of the mammalian nervous system by pseudorabies virus (PRV)

1994 • 70 citations

Role of glycoprotein gIII of pseudorabies virus in virulence

1988 • 70 citations

Role of essential glycoproteins gII and gp50 in transneuronal transfer of pseudorabies virus from the hypoglossal nerves of mice

1993 • 70 citations

Role of apical and basolateral membranes in replication of human cytomegalovirus in polarized retinal pigment epithelial cells

1996 • 69 citations

Chemical Cross-Linking of Virion Envelope and Tegument Proteins of Herpes Simplex Virus Type 1

1994 • 69 citations

Glycoprotein D-negative pseudorabies virus can spread transneuronally via direct neuron-to-neuron transmission in its natural host, the pig, but not after additional inactivation of gE or gI

1996 • 68 citations

Glycoprotein E of pseudorabies virus and homologous proteins in otheralphaherpesvirinae

1994 • 67 citations

Disseminated Neonatal Herpes Simplex Virus Type 1 from a Maternal Breast Lesion

1983 • 67 citations

Antibody-induced and cytoskeleton-mediated redistribution and shedding of viral glycoproteins, expressed on pseudorabies virus-infected cells

1997 • 67 citations

Olfactory mucosa in herpes simplex encephalitis.

1979 • 66 citations

Projections from rabbit caudal medulla to C1 and A5 sympathetic premotor neurons, demonstrated with phaseolus leucoagglutinin and herpes simplex virus

1992 • 66 citations

The endoplasmic reticulum of purkinje neuron body and dendrites: Molecular identity and specializations for Ca2+ transport

1992 • 65 citations

Factors that contribute to the transneuronal spread of herpes simplex virus

1997 • 65 citations

Transneuronal transfer of herpes simplex virus type 1 (HSV 1) from mixed limb nerves to the CNS. I. Sequence of transfer from sensory, motor, and sympathetic nerve fibres to the spinal cord

1992 • 65 citations

β-galactosidase expressing recombinant pseudorabies virus for light and electron microscopic study of transneuronally labeled CNS neurons

1991 • 64 citations

The UL20 gene product of pseudorabies virus functions in virus egress

1997 • 64 citations

Transolfactory spread of virus in herpes simplex encephalitis.

1980 • 64 citations

Complementation analysis of pseudorabies virus gE and gI mutants in retinal ganglion cell neurotropism

1994 • 64 citations

Herpes simplex encephalitis

1984 • 63 citations

The regulation of synthesis and properties of the protein product of open reading frame P of the herpes simplex virus 1 genome

1995 • 63 citations

Potential use of herpes simplex virus (HSV) vectors for gene therapy of neurological disorders

1997 • 63 citations

Direct and indirect retinohypothalamic projections to the supraoptic nucleus in the female albino rat

1994 • 63 citations

The gene encoding the gIII envelope protein of pseudorabies virus vaccine strain Bartha contains a mutation affecting protein localization

1989 • 62 citations

Cell surface proteoglycans are not essential for infection by pseudorabies virus

1995 • 61 citations

Identification of spinal interneurons antecedent to adrenal sympathetic preganglionic neurons using trans-synaptic transport of herpes simplex virus type 1

1995 • 61 citations

Deleting two amino acids in glycoprotein gI of pseudorabies virus decreases virulence and neurotropism for pigs, but does not affect immunogenicity

1993 • 61 citations

Neuroinvasive properties of herpes simplex virus type 1 glycoprotein variants are controlled by the immune response.

1996 • 61 citations

Neurons lying in the white matter of the upper cervical spinal cord project to the intermediolateral cell column

1997 • 59 citations

Species selective interaction of Alphaherpesvirinae with the “unspecific” immune system of the host

1993 • 59 citations

Adaptability in herpesviruses: glycoprotein D-independent infectivity of pseudorabies virus

1997 • 59 citations

Transneuronal viral labelling of rat heart left ventricle controlling pathways

1993 • 59 citations

Glycoprotein gH of Pseudorabies Virus is Essential for Penetration and Propagation in Cell Culture and in the Nervous System of Mice

1996 • 59 citations

Herpes simplex virus neurovirulence and productive infection of neural cells is associated with a function which maps between 0.82 and 0.832 map units on the hsv genome

1989 • 58 citations

The pseudorabies virus homology of the herpes simplex virus UL21 gene product is a capsid protein which is involved in capsid maturation

1992 • 58 citations

Zoster-like Disease in the Newborn Due to Herpes-Simplex Virus

1971 • 58 citations

Immunohistochemical identification of trigeminal ganglion neurons that innervate the mouse cornea: Relevance to intercellular spread of herpes simplex virus

1993 • 57 citations

Green fluorescent protein expressed by recombinant pseudorabies virus as an in vivo marker for viral replication

1997 • 57 citations

Epidemic Cutaneous Herpes Simplex in Wrestlers (Herpes Gladiatorum)

1965 • 57 citations

Transmission of Herpes Simplex Virus Type 1 Infection in Rugby Players

1984 • 57 citations

Replacement of Glycoprotein B Gene Sequences in Herpes Simplex Virus Type 1 Strain ANG by Corresponding Sequences of the Strain KOS Causes Changes of Plaque Morphology and Neuropathogenicity

1987 • 56 citations

Herpes Simplex Virus gD and Virions Accumulate in Endosomes by Mannose 6-Phosphate-Dependent and -Independent Mechanisms

1998 • 56 citations

The Herpes Simplex Virus Type 2 (HG52) Variant JH2604 Has a 1488 bp Deletion which Eliminates Neurovirulence in Mice

1989 • 56 citations

Host cell-specific growth advantage of pseudorabies virus with a deletion in the genome sequences encoding a structural glycoprotein

1988 • 56 citations

An avirulent ICP34.5 deletion mutant of herpes simplex virus type 1 is capable of in vivo spontaneous reactivation

1995 • 56 citations

Interneurons presynaptic to rat tail-flick motoneurons as mapped by transneuronal transport of pseudorabies virus: few have long ascending collaterals

1996 • 56 citations

Changes in excitability induced by herpes simplex viruses in rat dorsal root ganglion neurons

1986 • 55 citations

Progression of Different Nasally Instilled Viruses along Different Nervous Pathways in the Same Host

1938 • 55 citations

Herpes simplex viral infection of the mouse trigeminal ganglion. Immunohistochemical analysis of cell populations.

1992 • 55 citations

Putative site for the acquisition of human herpesvirus 6 virion tegument

1990 • 54 citations

Glycoprotein B is a specific determinant of herpes simplex virus type 1 neuroinvasiveness

1993 • 54 citations

Genetic variability of herpes simplex virus: development of a pathogenic variant during passaging of a nonpathogenic herpes simplex virus type 1 virus strain in mouse brain

1983 • 53 citations

Renal and adrenal sympathetic preganglionic neurons in rabbit spinal cord: tracing with Herpes simplex virus

1992 • 52 citations

Neuronal organization of the stapedius reflex pathways in the rat: a retrograde HRP and viral transneuronal tracing study

1989 • 52 citations

Influence of infectious dose upon productive replication and transynaptic passage of pseudorabies virus in rat central nervous system

1995 • 52 citations

Acquisition of neonatal HSV-1 infection from a paternal source contact

1983 • 52 citations

Involvement of glycoprotein C (gC) in adsorption of herpes simplex virus type 1 (HSV-1) to the cell

1991 • 52 citations

Ultrastructural and immunoperoxidase study of striatonigral neurons by means of retrograde axonal transport of herpes simplex virus

1978 • 52 citations

Characterization of domains of herpes simplex virus type 1 glycoprotein E involved in Fc binding activity for immunoglobulin G aggregates

1994 • 51 citations

PNMT-containing neurons in the rostral medulla oblongata (C1, C3 groups) are transneuronally labelled after injection of herpes simplex virus type I into the adrenal gland

1989 • 51 citations

Dissemination of wild-type and gC-, gE- and gI-deleted mutants of Aujeszky's disease virus in the maxillary nerve and trigeminal ganglion of pigs after intranasal inoculation

1995 • 51 citations

Selective spread of herpes simplex virus in the central nervous system after ocular inoculation

1989 • 51 citations

Pathogenesis of Herpes Simplex Virus Infection and Animal Models for Its Study

1992 • 51 citations

The virulence-determining genomic BamHI fragment 4 of pseudorabies virus contains genes corresponding to the UL15 (partial), UL18, UL19, UL20, and UL21 genes of herpes simplex virus and a putative origin of replication

1992 • 50 citations

Physiological Changes in Sympathetic Ganglia Infected With Pseudorabies Virus

1955 • 50 citations

Identification and characterization of the pseudorabies virus UL3.5 protein, which is involved in virus egress

1996 • 50 citations

A Rabbit Model of Focal Herpes Simplex Encephalitis

1986 • 50 citations

Herpes Simplex and Pseudorabies Viruses

1969 • 50 citations

Infection by Herpes Simplex Virus and Cells of Nervous System Origin: Characterization of a Non-permissive Interaction

1978 • 49 citations

Vaccines for varicella-zoster virus and cytomegalovirus: recent progress

1994 • 49 citations

Selective Lesions of Neural Pathways Following Viral Inoculation of the Olfactory Bulb

1993 • 48 citations

Transneuronal labelling of neurons in rabbit brain after injection of Herpes simplex virus type 1 into the renal nerve

1993 • 48 citations

Transmission of herpes simplex virus from father to neonate

1983 • 48 citations

Ultrastructural aspects of herpes simplex virus infection in organized cultures of mammalian nervous tissue.

1969 • 47 citations

Localization of nitric oxide synthase in the brain stem neural circuit controlling esophageal peristalsis in rats

1995 • 47 citations

Normal and 5-bromodeoxyuridine-inhibited development of herpes simplex virus

1966 • 47 citations

Proteins specified by the short unique region of the genome of pseudorabies virus play a role in the release of virions from certain cells

1986 • 47 citations

Two outbreaks of herpes simplex virus type 1 nosocomial infection among newborns

1986 • 46 citations

Release of pseudorabies virus from infected cells is controlled by several viral functions and is modulated by cellular components

1989 • 46 citations

Virus-Induced Immunopathology

1996 • 46 citations

The Interaction of Herpes Simplex Virus with Cultures of Peripheral Nervous Tissue: an Electron Microscopic Study

1973 • 46 citations

A Variant of Herpes Simplex Virus Type 2 Strain HG52 with a 1.5 kb Deletion in RL between 0 to 0.02 and 0.81 to 0.83 Map Units Is Non-neurovirulent for Mice

1989 • 45 citations

Dendritic morphology of cardiac related medullary neurons defined by circuit-specific infection by a recombinant pseudorabies virus expressing β-galactosidase

1995 • 44 citations

Defective viral vectors as agents for gene transfer in the nervous system

1997 • 44 citations

Tumour necrosis factor- , interferon- and interferon-beta exert antiviral activity in nervous tissue cells

1991 • 44 citations

Polarized Distribution of the Trans‐Golgi Network Marker TGN38 During the In Vitro Development of Neocortical Neurons: Effects of Nocodazole and Brefeldin A

1994 • 43 citations

Accessory human cytomegalovirus glycoprotein US9 in the unique short component of the viral genome promotes cell-to-cell transmission of virus in polarized epithelial cells

1996 • 43 citations

Oral inoculation with herpes simplex virus type 1 infects enteric neuron and mucosal nerve fibers within the gastrointestinal tract in mice

1996 • 43 citations

Altered pathogenesis in herpes simplex virus type 1 infection due to a syncytial mutation mapping to the carboxy terminus of glycoprotein B

1991 • 43 citations

Parasympathetic preganglionic neurons in the spinal cord involved in uterine innervation are cholinergic and nitric oxide‐containing

1995 • 43 citations

Interactions of Microtubule-Associated Protein MAP2 with Unpolymerized and Polymerized Tubulin and Actin Using a 96-Well Microtiter Plate Solid-Phase Immunoassay

1994 • 42 citations

Spread of herpes simplex virus and distribution of latent infection after intraocular infection of the mouse

1985 • 41 citations

The herpes simplex virus type 1 UL37 gene product is a component of virus particles

1994 • 41 citations

Development and chemical specificity of neurons

1982 • 41 citations

Electron microscopy of zosteriform herpes simplex infection in the mouse.

1972 • 41 citations

The Pathogenesis of Pseudorabies in Mice: Virus Replication at the Inoculation Site and Axonal Uptake

1975 • 41 citations

Ultrastructure and function in sympathetic ganglia isolated from rats infected with pseudorabies virus

1978 • 40 citations

Characterization of regions of herpes simplex virus type 1 glycoprotein E involved in binding the Fc domain of monomeric IgG and in forming a complex with glycoprotein I.

1995 • 39 citations

Tensor tympani reflex pathways studied with retrograde horseradish peroxidase and transneuronal viral tracing techniques

1986 • 39 citations

A Chicken Embryo Eye Model for the Analysis of Alphaherpesvirus Neuronal Spread and Virulence

1998 • 39 citations

Viral Encephalitis: Pathology, Diagnosis and Management

1986 • 39 citations

Emerging functions of alphaherpesvirus genes

1993 • 38 citations

A neurobiological approach to neurotropic viruses

1980 • 37 citations

Pseudorabies virus mutants as transneuronal markers

1995 • 37 citations

Phenotypic properties of herpes simplex virus 1 containing a derepressed open reading frame P gene

1996 • 37 citations

Retrograde transneuronal transport of Herpex simplex virus in the retina after injection in the superior colliculus, hypothalamus and optic chiasm

1989 • 36 citations

Loss of membrane excitability after herpes simplex virus infection in tissue-cultured nerve cells from adult mammals

1981 • 35 citations

Neuronal polarity: targeting of microtubule components into axons and dendrites

1991 • 35 citations

Intracellular Processing of Pseudorabies Virus Glycoprotein M (gM): gM of Strain Bartha Lacks N-Glycosylation

1997 • 35 citations

Histological study of the progression of herpes simplex virus in mice

1980 • 35 citations

Spread of herpes simplex virus (HSV) strains SC16, ANG, ANGpath and its glyC minus and GlyE minus mutants in DBA-2 mice.

1990 • 34 citations

Electrophysiological Changes of HSV-1-Infected Dorsal Root Ganglia Neurons in Culture

1981 • 34 citations

Principles of Neural Science (3rd ed.)

1993 • 34 citations

Identification of renal sympathetic preganglionic neurons in hamsters using transsynaptic transport of herpes simplex type 1 virus

1993 • 33 citations

Evidence that the gene for herpes simplex virus type 1 DNA polymerase accounts for the capacity of an intertypic recombinant to spread from eye to central nervous system

1988 • 33 citations

Visualization of Three-Dimensional Density Maps Reconstructed from Cryoelectron Micrographs of Viral Capsids

1996 • 33 citations

Varicella-zoster virus gpl and herpes simplex virus gE: Phosphorylation and Fc binding

1987 • 33 citations

Neuroanatomic organization of the parasympathetic bronchomotor system in developing sheep

1997 • 33 citations

Deleting valine-125 and cysteine-126 in glycoprotein gI of pseudorabies virus strain NIA-3 decreases plaque size and reduces virulence in mice

1993 • 33 citations

Spontaneous electrical activity induced by herpes virus infection in rat sensory neuron cultures

1985 • 32 citations

The herpes simplex virus UL20 protein compensates for the differential disruption of exocytosis of virions and viral membrane glycoproteins associated with fragmentation of the Golgi apparatus

1994 • 32 citations

Transneuronal labeling of neurons in rabbit brain after injection of herpes simplex virus type 1 into the aortic depressor nerve

1991 • 32 citations

Herpes simplex virus type 1 DNA sequences which direct spread of virus from comes to central nervous system

1986 • 32 citations

Precipitous clearance of herpes simplex virus antigens from the peripheral nervous systems of experimentally infected C57BL/10 mice.

1998 • 32 citations

Firefly Luciferase as a Marker for Herpesvirus (pseudorabies virus) Replication in Vitro and in Vivo

1991 • 30 citations

Neuron-specific restriction of a herpes simplex virus recombinant maps to the UL5 gene

1994 • 30 citations

The abundance of the herpes simplex virus type 1 UL37 tegument protein in virus particles is closely controlled.

1997 • 30 citations

DNA Replication and the Cell Cycle

2007 • 30 citations

Herpes virus-based vectors

1995 • 30 citations

Helper Virus-Free Herpes Simplex Virus-1 Plasmid Vectors for Gene Therapy of Parkinson's Disease and Other Neurological Disorders

1997 • 29 citations

Differential tropism of pseudorabies virus for sensory neurons in the cat

1997 • 29 citations

Toxicity and Neuronal Infection of a HSV-1 ICP34.5 Mutant in Nude Mice

1998 • 29 citations

STUDIES ON HERPETIC INFECTION IN MICE

1943 • 29 citations

Co-localization of NOS and NMDA receptor in esophageal premotor neurons of the rat

1995 • 29 citations

Analysis of the Relationship between Cellular Thymidine Kinase Activity and Virulence of Thymidine Kinase‐Negative Herpes Simplex Virus Types 1 and 2

1995 • 28 citations

HSV-1 virulence for mice by the intracerebral route is encoded by the BamHI-L DNA fragment containing the cell fusion gene

1987 • 27 citations

Transformation of Golgi membrane into the envelope of herpes simplex virus in rat anterior pituitary cells.

1989 • 27 citations

Mapping neuroinvasiveness of the herpes simplex virus type 1 encephalitis-inducing strain 2762 by the use of monoclonal antibodies

1992 • 27 citations

Localization of a herpes simplex virus neurovirulence gene dissociated from high-titer virus replication in the brain

1988 • 27 citations

Anterograde transport of HSV-1 and HSV-2 in the visual system

1992 • 26 citations

Effects of HSV-1, a neurotropic virus, on the hypothalamic-pituitary-adrenocortical axis in rats

1995 • 26 citations

Studies on endoplasmic reticulum—Golgi complex cycling pathway in herpes simplex virus-infected and brefeldin A-treated human fibroblast cells

1992 • 26 citations

HSV as a gene transfer vector for the nervous system

1995 • 26 citations

CNS tumor therapy by attenuated herpes simplex viruses.

1994 • 25 citations

Scrum-pox caused by herpes simplex virus.

1979 • 25 citations

HSV-1 Neuroinvasiveness

1993 • 25 citations

Spread of Herpes simplex virus type-1 (Miyama +GC strain) to the central nervous system after intraperitoneal inoculation: the role of the myenteric plexus of the gut

1989 • 24 citations

The gE and gI homologs from two alphaherpesviruses have conserved and divergent neuroinvasive properties

1997 • 24 citations

DNA Replication and the Cell Cycle

1993 • 24 citations

Pseudorabies virus recombinants expressing functional virulence determinants gE and gI from bovine herpesvirus 1.1

1997 • 24 citations

The transneuronal spread phenotype of herpes simplex virus type 1 infection of the mouse hind footpad

1997 • 24 citations

The Role of Herpes Simplex Virus Glycoproteins in Immune Evasion

1992 • 24 citations

Herpes simplex virus particles are unable to traverse the secretory pathway in the mouse L-cell mutant gro29

1990 • 24 citations

Mutations in the UL53 gene of HSV-1 abolish virus neurovirulence to mice by the intracerebral route of infection

1992 • 24 citations

In SituPCR Localization of Herpes Simplex Virus DNA Sequences in Disseminated Neonatal Herpes Encephalitis

1994 • 24 citations

The Origins of the Small DNA Tumor Viruses

1994 • 23 citations

Invasion of Cranial Nerves and Brain Stem by Herpes Simplex Virus Inoculated into the Mouse Tongue

1988 • 23 citations

Necropsy study of the olfactory portal of entry in herpes simplex encephalitis

1983 • 23 citations

Involvement of Golgi apparatus and a restructured nuclear envelope during biogenesis and transport of herpes simplex virus glycoproteins.

1985 • 23 citations

Molecular analysis of a neurovirulent herpes simplex virus type 2 strain with reduced thymidine kinase activity

1993 • 23 citations

Transneuronal labeling in hamster brainstem following lingual injections with Herpes simplex virus-1

1995 • 23 citations

A murine model of pseudorabies virus latency

1992 • 22 citations

Herpes simplex virus vectors for gene transfer to the nervous system.

1997 • 22 citations

Experimental Infection of Inbred Mice with Herpes Simplex Virus. V. Investigations with a Virus Strain Non-lethal after Peripheral Infection

1982 • 22 citations

A cellular function is required for pseudorabies virus envelope glycoprotein processing and virus egress

1992 • 22 citations

Conservation of the Architecture of the Golgi Apparatus Related to a Differential Organization of Microtubules in Polykaryocytes Induced bysyn−Mutants of Herpes Simplex Virus 1

1998 • 22 citations

Transneuronal labelling of CNS neurons with herpes simplex virus

1994 • 21 citations

Viral Encephalitis. Pathology, Diagnosis and Management

1987 • 21 citations

The use of herpes simplex virus-based vectors for gene delivery to the nervous system

1997 • 21 citations

Viral labelling of synaptically connected neurons.

1997 • 21 citations

The JH2604 deletion variant of herpes simplex virus type 2 (HG52) fails to produce necrotizing encephalitis following intracranial inoculation of mice

1990 • 21 citations

Alteration of the electrophysiological activity in symphathetic ganglia infected with a neurotropic virus. I. Presynaptic origin of the spontaneous bioelectric activity

1982 • 21 citations

Phosphorylation of Neurotropic Alphaherpesvirus Envelope Glycoproteins: Herpes Simplex Virus Type 2 gE2 and Pseudorabies Virus gl

1993 • 21 citations

HSV (Type 1) infection of the trigeminal complex

1990 • 21 citations

Natural Resistance Mechanisms in Herpes Simplex Virus Infections

1985 • 21 citations

Virulence Is not Conserved in Recombinants between Herpes Simplex Virus Types 1 and 2

1987 • 20 citations

The RL neurovirulence locus in herpes simplex virus type 2 strain HG52 plays no role in latency

1991 • 18 citations

Microtubules and intermediate filaments of herpes simplex virus infected cells

1987 • 18 citations

Second-Strength PPD Test (Cont.)

1971 • 18 citations

The roles of herpes simplex virus in neuroscience

1997 • 18 citations

Neonatal herpes simplex virus infections: pathogenesis and therapy.

1992 • 17 citations

Simian Agent 8 (SA8): Morphogenesis and Ultrastructure

1993 • 16 citations

Herpes simplex virus. Pathogenesis, immunobiology and control.

1992 • 15 citations

Immunohistochemical Studies on the Transneuronal Spread of Virulent Herpes Simplex Virus Type 2 and Its US3 Protein Kinase‐Deficient Mutant after Ocular Inoculation

1996 • 15 citations

An electron microscopic study of Aujeszky's disease

1973 • 15 citations

GROWTH OF HERPES SIMPLEX VIRUS IN TRANSFORMED GLIAL AND NEURONAL CELLS IN TISSUE CULTURE

1973 • 15 citations

Enzymatic Activity, Ultrastructure and Function in Ganglia Infected with a Neurotropic Virus

1979 • 15 citations

The herpes simplex virus type 1 ribonucleotide reductaseis required for acute retinal disease

1997 • 15 citations

Tyrosine Sulfation of Varicella-Zoster Virus Envelope Glycoprotein gpI

1993 • 14 citations

Early adrenal infection by herpes simplex virus type-1 (Miyama + GC strain): special reference to inoculation dose and spread from the adrenal to the central nervous system

1987 • 14 citations

Identification of sympathetic preganglionic neurons controlling the small intestine in hamsters using a recombinant herpes simplex virus type-1

1997 • 14 citations

Pseudorabies virus as a transneuronal tract tracing tool: specificity and applications to the sympathetic nervous system.

1994 • 12 citations

CNS innervation of the urinary bladder demonstrated by immunohistochemical study for c-fos and pseudorabies virus

1997 • 11 citations

Latency competence of herpes simplex virus strains ANG, ANGpath and its gC and gE minus mutans.

1990 • 11 citations

The Role of Herpes Simplex Virus Thymidine Kinase Expression in Pathogenesis and Latency

1994 • 11 citations

Replacement of glycoprotein B gene in the herpes simplex virus type 1 strain ANGpath DNA by that originating from nonpathogenic strain KOS reduces the pathogenicity of recombinant virus.

1994 • 11 citations

Gene therapy for pediatric brain tumors

1997 • 10 citations

An Intertypic Herpes Simplex Virus Helicase-Primase Complex Associated with a Defect in Neurovirulence Has Reduced Primase Activity

1998 • 10 citations

Regulation of Acetylcholine synthesis in normal and neurotropic viral infected sympathetic ganglia

1982 • 9 citations

Study of transneuronal passage of pseudorabies virus in rat central nervous system by use of immunohistochemistry and in situ hybridization.

1995 • 9 citations

The Bovine Herpesvirus Type 1 UL3.5 Open Reading Frame Encodes a Virion Structural Protein

1998 • 9 citations

Zoster-like Disease in Infants and Young Children

1971 • 8 citations

A quantitative assay of retrograde transported HSV in the trigeminal ganglion.

1992 • 8 citations

Perspectives for the gene therapy of malignant gliomas by suicide gene transfer.

1997 • 8 citations

Neurovirulence of Herpes Simplex Virus Type 1 Accessory Gene Mutants

1994 • 7 citations

Immunohistochemical analysis of pseudorabies virus spread through neurons innervating the eyeball*1

1995 • 7 citations

Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes

1994 • 7 citations

Study of transneuronal passage of pseudorabies virus in rat central nervous system by use of immunohistochemistry and in situ hybridization

1995 • 6 citations

Regions US6 and US7 of herpes simplex virus type 1 DNA encoding glycoproteins D and I may influence neuroinvasivity.

1994 • 5 citations

Transneuronal spread of the pseudorabies virus after injection into the central nucleus of the amygdala in the rat.

1994 • 4 citations

Apical expression of herpes simplex virus type 2 glycoproteins in human neuroblastoma cells

1991 • 3 citations

Ribonucleotide Reductase and the Ocular Virulence of Herpes Simplex Virus Type 1

1994 • 3 citations

Generation of recombinant herpes simplex virus type 1 to be used for automatic tract tracing.

1994 • 2 citations